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Price Family Foundation funds research collaboration between Albert Einstein College of Medicine and University of Oklahoma
Date:2/4/2014

February 4, 2014 (BRONX, NY) When the foe is a disease-causing microbe, identifying the structure of its component proteins can greatly aid efforts to kill or disable it. Research to gain this knowledge will be bolstered by a $3 million grant from The Price Family Foundation. The gift to Albert Einstein College of Medicine of Yeshiva University and the University of Oklahoma funds a research collaboration to investigate the structural biology of the key proteins of anaerobic microorganisms (those that don't use oxygen).

The research consortium, led at Einstein by Vern Schramm, Ph.D., Steven Almo, Ph.D., and James Love, Ph.D., will focus specifically on Clostridium difficile, a notorious bacterial species that infects the intestinal tract and that the U.S. Centers for Disease Control and Prevention considers an "urgent" health threat.

Toxins produced by C. difficile can damage the lining of the colon, causing colitis. Each year in the U.S., infections with this microbe sicken at least 250,000 people and cause at least 14,000 deaths. The joint project is aimed at finding better treatments for C. difficile infections. It will capitalize on Einstein's expertise in structural biology and its high-throughput analytic capabilities along with OU's expertise in anaerobic microbiology and chemistry.

"Michael Price and his family have a long history of support to Einstein and biomedical research around the country," said Dr. Schramm, professor and chair of biochemistry and Ruth Merns Chair in Biochemistry at Einstein. "This new
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Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

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