Navigation Links
Prenatal testosterone levels influence later response to reward
Date:11/5/2012

els are also heightened during critical periods of fetal brain development, but the impact of such prenatal surges in sex hormone levels on subsequent adult brain and behavioral development has received relatively little attention.

"This study is the first to directly examine whether testosterone in fetal development predicts tendencies later in life to engage in approach-related behavior (e.g., fun-seeking, impulsivity, reward responsivity) and also how it may influence later brain development that is relevant to such behaviors," said first author Lombardo.

In this study, they tested a unique cohort of boys, 8 years of age, whose fetal testosterone had been previously measured from amniotic fluid at 13 weeks gestation. The boys were scanned with functional magnetic resonance imaging technology to assess changes in brain activity while viewing pictures of negative (fear), positive (happy), neutral, or scrambled faces.

They found that increased fetal testosterone predicted more sensitivity in the brain's reward system to positively, compared to negatively, valenced facial cues. This means that reward-related brain regions of boys with higher fetal testosterone levels respond more to positive facial emotion compared to negative facial emotion than boys who with smaller levels of fetal testosterone.

In addition, increased fetal testosterone levels predicted increased behavioral approach tendencies later in life via its influence on the brain's reward system. Lombardo explained, "This work highlights how testosterone in fetal development acts as a programming mechanism for shaping sensitivity of the brain's reward system later in life and for predicting later tendency to engage in approach-related behaviors. These insights may be especially relevant to a number of neuropsychiatric conditions with skewed sex ratios and which affect approach-related behavior and the brain's reward system."

Dr. John Krystal, Editor of Biolog
'/>"/>

Contact: Rhiannon Bugno
Biol.Psych@utsouthwestern.edu
214-648-0880
Elsevier
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Tracking the effects of prenatal alcohol exposure through to 9 years of age
2. Prenatal whole genome sequencing: Just because we can, should we?
3. Prenatal micronutrient, food supplementation intervention in Bangladesh decreases child death rate
4. Prenatal exposure to air pollution linked to childhood obesity
5. Testosterone regulates solo song of tropical birds
6. Testosterone-fuelled infantile males might be a product of Moms behaviour
7. New genes discovered for adult BMI levels
8. Measuring mercury levels: Nano-velcro detects water-borne toxic metals
9. High levels of DDT in breast milk
10. Climate change could increase levels of avian influenza in wild birds
11. Low oxygen levels may decrease life-saving protein in spinal muscular atrophy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... 2014) – A majority of Madagascar,s 101 species of ... serious consequences for the rainforests they call home. A ... impacts lemurs can have on rainforest tree populations, which ... have on the region,s rich biodiversity. , A large ... by lemurs. Lemurs in turn disperse the seeds ...
(Date:11/3/2014)... Nov. 3, 2014 Research and Markets ... Therapy - Technologies, Markets and Companies" to their offering. ... technologies and methods, which have already started to play an ... transplantation is replacing the old fashioned bone marrow transplants. Role ... is bound to become a part of medical practice. ...
(Date:11/3/2014)... Nov. 3, 2014  NeuroSigma ® , Inc. ... sciences company focused on commercialization of its non-invasive ... the treatment of neurological and neuropsychiatric disorders, announced ... has issued a Notice of Allowance for Mexican ... co-owned by NeuroSigma and the Regents of the ...
Breaking Biology News(10 mins):Gardeners of Madagascar rainforest at risk 2Gardeners of Madagascar rainforest at risk 3Global Cell Therapy - Technologies, Markets and Companies: 2014 Report 2Global Cell Therapy - Technologies, Markets and Companies: 2014 Report 3NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 2NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 3
... the impact of student research on life at American University,s ... Following a 2009 study at American University,s main dining ... dishes used when trays were removed, trays have mostly gone ... the first time, a new paper coauthored by AU professor ...
... Houston faculty members have been named Charter Fellows of ... contributions to scientific and technological innovation. UH faculty ... Paul Chu, a physics professor and chief scientist of ... Dan Luss, a professor in chemical and biomedical engineering, ...
... (H2S) may play a wide-ranging role in staving off ... print in the journal Molecular and Cellular Biology ... explores the compound,s plethora of potential anti-aging pathways. ... important endogenous signaling molecule because of its significant effects ...
Cached Biology News:Going trayless study shows student impact 2Going trayless study shows student impact 3National Academy of Inventors honors 3 University of Houston professors 2National Academy of Inventors honors 3 University of Houston professors 3Hydrogen sulfide: The next anti-aging agent? 2
(Date:11/22/2014)... (PRWEB) November 21, 2014 Prominent ... investors will gather on December 3rd at Genetic ... Conferences series. GeneticRx will take place at the ... School and will discuss the present and future ... exon skipping, and gene editing—as well as the ...
(Date:11/22/2014)... 22, 2014 Respiratory therapy students ... proper management of life-like respiratory ailments using the ... . Grand Rapids-based, Michigan Instruments Inc. developers of ... of the respiratory simulation units to the pro-gram, ... Valley and Muskegon Community College are collaborating to ...
(Date:11/21/2014)... USA (PRWEB) November 19, 2014 The ... our lives was shared with more than 200 primary ... postgraduate students from the University of Otago Physics Department ... . The Otago students, members of the university’s OSA/SPIE ... Zealand in early September, giving children from small, rural ...
(Date:11/21/2014)... The November 2014 issue of BioTechniques ... access journal featuring the following articles:, , ... photoresponsiveness in the retina , DNA from ... using chromogenic substrates in zebrafish , Re-use ... electrophoresis , Nuclear LC3-positive puncta in stressed ...
Breaking Biology Technology:Pioneering Academics and Key Industry Leaders to Discuss Rare Diseases and the Emergence of New Genetic Medicines at Genetic Rx on December 3rd 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 3Optics and photonics outreach programs share science, spark fascination with light 2Optics and photonics outreach programs share science, spark fascination with light 3BioTechniques: The International Journal of Life Science Methods Announces the Publication of the November 2014 Issue—Available in Print and Online 2BioTechniques: The International Journal of Life Science Methods Announces the Publication of the November 2014 Issue—Available in Print and Online 3
... ST. LOUIS, Jan. 20, 2012   On Tuesday, January ... will vote on a shareholder proposal to create a ... with its chemical products and genetically modified organisms (GMOs). ... strongest signals to date that the biotech food conglomerate ...
... PORTLAND, Ore., Jan. 20, 2012 Boulder Diagnostics Inc. ... into a license and collaboration agreement to develop rapid ... a highly specific dye technology developed at PSU. Under ... Department of Chemistry, and PSU will be entitled to ...
... Berkeley, CA A team of scientists from Bio ... the feedstocks for advanced biofuels and renewable chemicals production ... to extract the all the major sugars in seaweed ... making seaweed a cost-effective, renewable source of biomass. ...
Cached Biology Technology:Monsanto Attempts to Lockout Socially Responsible Shareholder at Annual Meeting 2Boulder Diagnostics Licenses Novel Rapid Detection Technology for Homocysteine and Related Compounds from Portland State University 2Bio architecture lab technology converts seaweed to renewable fuels and chemicals 2