Navigation Links
Prenatal meth exposure linked to abnormal brain development
Date:4/16/2009

ST. PAUL, Minn. A first of its kind study examining the effects of methamphetamine use during pregnancy has found the drug appears to cause abnormal brain development in children. The research is published in the April 15, 2009, online issue of Neurology, the medical journal of the American Academy of Neurology.

"Methamphetamine use is an increasing problem among women of childbearing age, leading to an increasing number of children with prenatal meth exposure," said study author Linda Chang, MD, with the John A. Burns School of Medicine, University of Hawai`i at Mānoa in Honolulu. "But until now, the effects of prenatal meth exposure on the developing brain of a child were little known."

For the study, brain scans were performed on 29 three- and four-year-old children whose mothers used meth while pregnant and 37 unexposed children of the same ages. The MRI scans used diffusion tensor imaging to help measure the diffusion of molecules in a child's brain, which can indicate abnormal microscopic brain structures that might reflect abnormal brain development.

The scans showed that children with prenatal meth exposure had differences in the white matter structure and maturation of their brains compared to unexposed children. The children with prenatal meth exposure had up to four percent lower diffusion of molecules in the white matter of their brains.

"Our findings suggest prenatal meth exposure accelerates brain development in an abnormal pattern," said Chang. "Such abnormal brain development may explain why some children with prenatal meth exposure reach developmental milestones later than others."

Studies have shown that prenatal meth exposure can lead to increased stress and lethargy and poorer quality of movement for infants.

"While we don't know how prenatal meth exposure may lead to lower brain diffusion, less diffusion of molecules in white matter typically reflects more compact axonal fibers in the brain," said Chang. "This is consistent with our prior findings of smaller subcortical structures in children with prenatal meth exposure, which is the portion of the brain immediately below the cerebral cortex."

Long-term studies are under way to determine if the brain differences found in children with prenatal exposure to meth will normalize with age.


'/>"/>

Contact: Tina Shelton
sheltont@hawaii.edu
808-692-0897
University of Hawaii at Manoa
Source:Eurekalert  

Related biology news :

1. MIT: Prenatal arsenic exposure detected in newborns
2. Trainor Lab characterizes gene essential for prenatal development of nervous system
3. Moderate prenatal exposure to alcohol and stress in monkeys can cause touch sensitivity
4. Low sperm count may be associated with prenatal testosterone excess
5. Microarray analysis improves prenatal diagnosis
6. Meth exposure in young adults leads to long-term behavioral consequences
7. UCR engineers to develop new tool to measure how environmental exposures affect health
8. Researchers developing device to predict proper light exposure for human health
9. Nanoparticle exposures happen, says expert
10. Time spent in car drives up air pollution exposure
11. Low exposure to asbestos-like mineral from Montana vermiculite may up lung disease risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Prenatal meth exposure linked to abnormal brain development
(Date:2/21/2017)... N.Y. and PORTLAND, Ore. ... ) and the Avamere Family of Companies (Avamere Health ... today announced a six-month research study that will apply ... improve eldercare at senior living and health centers. By ... Avamere hopes to gain insights into physical and environmental ...
(Date:2/16/2017)... , Feb. 16, 2017  Genos, a community ... that it has received Laboratory Accreditation from the ... is presented to laboratories that meet stringent requirements ... scientifically rigorous processes. "Genos is committed ... laboratory practices. We,re honored to be receiving CAP ...
(Date:2/13/2017)... , Feb. 13, 2017  RSA Conference -- RSA, ... that is designed to enhance fraud detection and ... in the RSA Fraud & Risk Intelligence Suite. ... to leverage additional insights from internal and external ... better protect their customers from targeted cybercrime attacks. ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... -- BioPharmX Corporation (NYSE MKT: BPMX), a specialty pharmaceutical ... reported financial results for the quarter and year ... update on the company,s clinical development efforts and ... pleased to report that last year was a ... Krammer. "We achieved key clinical milestones and attracted ...
(Date:3/23/2017)... NEW YORK , March 23, 2017 ... ... causes of death, putting significant strain on health care systems, ... of cancer diagnoses rises, so too does the development of ... with minimum side effects. Among the many types of cancer ...
(Date:3/23/2017)... , March 23, 2017 In ... four equities in the Biotech industry: Sangamo Therapeutics Inc. ... Inc. (NYSE MKT: SYN), and Regulus Therapeutics Inc. (NASDAQ: ... , 2017, Credit Suisse upgraded its rating on Pharmaceuticals/Biotechnology to "Overweight" from ... their free report at: ...
(Date:3/22/2017)... Mass. (PRWEB) , ... March 22, 2017 , ... ... scale up human tissue regeneration from small lab samples to full-size tissues, bones, ... how to establish a vascular system that delivers blood deep into the developing ...
Breaking Biology Technology: