Navigation Links
Premature babies at risk of ill health in later life, research suggests
Date:10/18/2011

Young adults who were born prematurely show multiple biological signs of risks to future health, research from Imperial College London has found. The scientists, reporting their findings tomorrow in the journal Pediatric Research, say that the research indicates that urgent work is now needed to monitor preterm babies into adulthood to improve the detection of early signs of disease.

The study of 48 volunteers aged 18-27 found that those who were born at 33 weeks of gestation or less had higher blood pressure, more fat tissue despite having a normal Body Mass Index, and more fat in their muscle and liver. These traits are linked to heart and circulatory disease and type 2 diabetes. The differences in fat around the abdomen were most marked in men.

The number of preterm babies born each year is rising, and in developed countries, around 2 per cent of babies are born before 33 weeks of gestation.

Medical advances mean that a higher proportion of babies born early are surviving: 90 per cent of infants born before 33 weeks will go home. However, a few studies have suggested that the impact of preterm birth persists into adulthood, putting premature babies at risk of ill health in later life. The biological pathways involved are unknown.

"This was only a small study but the differences we found were quite striking," said Professor Neena Modi, the lead investigator in the study from the Department of Medicine at Imperial College London. "The results suggest that we need to monitor the health of premature babies beyond infancy and childhood. Preterm men and women might be at greater risk of cardiovascular and metabolic diseases but if we look out for the warning signs, we can help them to stay healthy with lifestyle interventions, and treatment where appropriate."

Professor Neena Modi and her colleagues used whole body magnetic resonance imaging (MRI) and advanced chemical profiling techniques to investigate what biological differences might be present in young adults who were born prematurely.

They found that even though the preterm subjects did not have a higher Body Mass Index (BMI), they did have more fat tissue around their abdomens and in their muscle and liver.

Nuclear magnetic resonance (NMR) spectroscopy revealed differences in the chemical makeup of their urine, with preterm subjects producing more metabolites associated with inflammation, which is in keeping with the higher blood pressure and greater fat found in the preterm subjects.

The study involved 23 healthy men and women born before 33 weeks and 25 healthy men and women born at full term. The preterm volunteers were recruited with the help of Bliss, a national UK premature and sick baby charity.


'/>"/>

Contact: Colin Smith
cd.smith@imperial.ac.uk
44-207-594-6712
Imperial College London
Source:Eurekalert

Related biology news :

1. Researchers find hormone that predicts premature death in kidney patients
2. Socioeconomic class and smoking linked to premature menopause
3. Premature aging caused by some HIV drugs, study shows
4. Scripps Research scientists create new genetic model of premature aging diseases
5. Major breakthrough in preventing premature birth announced by NIH/WSU
6. Tiny RNA molecules control labor, may be key to blocking premature birth
7. Students design early labor detector to prevent premature births
8. Probiotics help extremely premature infants gain weight
9. Periodic heart rate decelerations in premature infants
10. Prevention is key research goal for premature babies, scientists say
11. Women with endometriosis need special care during pregnancy to avoid risk of premature birth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... 24, 2017 Janice Kephart , ... Identity Strategy Partners, LLP (IdSP) , today issues ... President Trump,s March 6, 2017 Executive Order: ... vetting can be instilled with greater confidence, enabling ... all refugee applications are suspended by until at ...
(Date:4/13/2017)... , April 13, 2017 UBM,s Advanced ... will feature emerging and evolving technology through ... Innovation Summits will run alongside the expo portion of ... sessions, panels and demonstrations focused on trending topics within ... advanced design and manufacturing event will take place June ...
(Date:4/11/2017)... 2017 No two people are believed ... New York University Tandon School of Engineering and ... that partial similarities between prints are common enough ... phones and other electronic devices can be more ... lies in the fact that fingerprint-based authentication systems ...
Breaking Biology News(10 mins):
(Date:6/20/2017)... (PRWEB) , ... June 20, 2017 , ... ... Linda Robbie, PhD, a well-versed leader with extensive assay development and biomarker expertise, ... Cambridge Biomedical is a Boston CRO specializing in bio-analytical assay development and sample ...
(Date:6/19/2017)... ... June 19, 2017 , ... As Vice President, Product ... including training, implementation, support, and client process and SOP development. , Mr. Guinter ... held leadership roles for service providers and top-tier pharmaceuticals, and as an independent ...
(Date:6/19/2017)... ... , ... A colony of healthy honey bees is like a superorganism--individual bees ... nectar containing nutrients necessary for growth and survival. Better nutrition gives the colony a ... to a decline in honey bee health. Sick and weakened bees diminish the colony's ...
(Date:6/16/2017)... ... 2017 , ... CTNext , Connecticut’s go-to resource for entrepreneurial support, today ... at Chelsea Piers in Stamford. , Nine finalists, all of whom are Connecticut-based companies ... opportunity to secure $10,000 awards to help support business growth. The winners included:, ...
Breaking Biology Technology: