Navigation Links
Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding
Date:9/18/2007

An algorithm utilizing structure mapping and thermodynamics is introduced for RNA pseudoknot prediction. The method finds the minimum free energy in the context of the biological folding direction (5 to 3) of RNA sequences.

It also identifies information about the flexibility of the RNA. Mapping methods are used to build and analyze the folded structure and add important 3D structural considerations. The model suggests that many biological RNA molecules are optimized by natural selection to fold correctly in the natural context and that stable intermediate RNA secondary structure can persist that anticipates pseudoknot formation.

The model will be published in the online, open-access journal PLoS ONE on September 19.


'/>"/>

Contact: Wayne Dawson
wayne.dawson@it-chiba.ac.jp
Public Library of Science
Source:Eurekalert

Page: 1

Related biology news :

1. Understanding biases in epidemic models important when making public health predictions
2. Modification of program enables prediction of gene transcription
3. Computers close in on protein structure prediction
4. Sensor web simulation investigates technique to improve prediction of pollution across the globe
5. Improved predictions of warming-induced extinctions sought
6. University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
7. Purdue proves concept of using nano-materials for drug discovery
8. An entropy-based gene selection method for cancer classification using microarray data
9. Newly Discovered Compound Blocks Known Cancer-Causing Protein
10. Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
11. New methods of gene delivery using lasers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... you want your doctor to know what goes wrong with ... good idea to know what "normal" actually is. That,s where ... of the FASEB Journal comes in. ... transcriptomea key set of molecules that can help scientists "see" ... time. What,s more, they found never-before-detected gene activity and that ...
(Date:9/30/2014)... in German . ... to risky situations such as exposure to predators. Researchers ... in a long-term study on different populations of great ... and ambient temperature. High metabolic rates and low temperatures ... scenarios birds were more likely to approach potential predators. ...
(Date:9/30/2014)... perilous threats in today,s ocean. From overfishing and ... coral ecosystems are disappearing at unprecedented rates around ... corals surrounding the island of Moorea in French ... environment: coral guard-crabs. New research from the National ... Seabird McKeon and the museum,s predoctoral fellow Jenna ...
Breaking Biology News(10 mins):Scientists identify which genes are active in muscles of men and women 2Risky metabolism 2Smithsonian scientists discover coral's best defender against an army of sea stars 2
... Clinic researchers have designed a new tool for identifying ... Stephen Ekker, Ph.D., succeeded in switching individual genes off ... development. The study appears in the journal Nature ... on health-related problems such as how cancerous cells spread, ...
... The May issue of JAMIA, the top-ranked journal reporting ... scientific researchin print and onlineon healthcare,s hottest HIT-related topics, ... Editor-in chief Lucila Ocho-Machado bullets some of the rich ... "A secure protocol for protecting the identity ...
... NEW BRUNSWICK, N.J. From a bucket of seawater, scientists ... organisms as different as coral reefs and human disease. By ... demonstrated a possible way to address diverse questions such as ... it is about some Antarctic algae that allows them to ...
Cached Biology News:In a genetic research first, Mayo Clinic turns zebrafish genes off and on 2In a genetic research first, Mayo Clinic turns zebrafish genes off and on 3JAMIA reports on people, their information needs and social networks 2From a bucket of seawater, new understanding of the ocean 2From a bucket of seawater, new understanding of the ocean 3
(Date:9/30/2014)... Proove Biosciences , the commercial and research leader in ... test built upon research from their published P.A.I.N. Study. ... physicians with an objective way to understand theirs patient’s ... individuals. With this new test, physicians will be able ... that will affect their pain tolerance. , The P.A.I.N. ...
(Date:9/30/2014)... , September 30, 2014 ... browsing of chemistry in documents ... solutions and consulting services for life science research, ... and generate Markush structures from documents. ... intellectual property, however generating and understanding Markush structures ...
(Date:9/30/2014)... and ROCKVILLE, Md., Sept. 30, 2014 BioHealth ... on commercializing market-relevant biohealth innovations and increasing access to ... announced today that venture capitalist, Tania Fernandez , ... advisor. Dr. Fernandez will be a member of the ... will provide up to $50 million in seed and ...
(Date:9/30/2014)... September 30, 2014 The custom stainless ... Boston Product Show 2014. The Boston Area Chapter of ... 23rd annual, day-long event for Wed., Oct. 1 at ... to be the largest in ISPE Boston’s long history, ... of 3,000 attendees expected. , HOLLOWAY AMERICA President ...
Breaking Biology Technology:Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3ChemAxon Introduces ChemCurator for Chemical Information Extraction and Markush Structure Creation 2Seasoned Life Sciences Venture Capitalist Tania Fernandez Joins BHI to Help Manage New BioHealth Gap Fund 2HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 2HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 3
... Contract Research Organization Exceeds Expectations, MEMPHIS, ... Contract Research,Organization exclusively focused on oncology, announced ... exceeded projections as the company continues,to experience ... to,ACORN,s ability to consistently exceed client expectations, ...
... Pharma, Inc., a,diversified specialty pharmaceutical company, announced ... issues in the treatment of moderate to,severe ... dry eye medication Lacrisert(R),(hydroxypropyl cellulose ophthalmic insert), ... helps to retain,moisture, stabilize the tear film, ...
... -- 3SBio Inc. (Nasdaq:,SSRX), a leading biotechnology company ... primarily in China,today announced that it has filed ... for approval of NuLeusin for the treatment of ... is expected to,be the only treatment of this ...
Cached Biology Technology:ACORN CRO Continues Growth in Strong Third Quarter 2Dry Eye Survey: Ophthalmologists Cite Treatment Limitations/Gaps in Treatment of Moderate to Severe Dry Eye 2Dry Eye Survey: Ophthalmologists Cite Treatment Limitations/Gaps in Treatment of Moderate to Severe Dry Eye 3Dry Eye Survey: Ophthalmologists Cite Treatment Limitations/Gaps in Treatment of Moderate to Severe Dry Eye 4Dry Eye Survey: Ophthalmologists Cite Treatment Limitations/Gaps in Treatment of Moderate to Severe Dry Eye 53SBio Inc. Files for SFDA Approval of NuLeusin 23SBio Inc. Files for SFDA Approval of NuLeusin 33SBio Inc. Files for SFDA Approval of NuLeusin 4
Human RELT/TNFRSF19L MAb (Clone 238104)...
...
... assay kit measures NOS activity by monitoring ... This assay is simple, sensitive, and specific ... with both crude and purified enzyme preparations. ... for 50 total reactions. Radiolabeled arginine and ...
Human TSLP MAb (Clone 258136)...
Biology Products: