Navigation Links
Predicting risk of stroke from one's genetic blueprint
Date:2/25/2009

l was able to predict an individual's risk of cardioembolic stroke with an accuracy of 86 percent. Ultimately, Ramoni envisions doctors using it as a diagnostic tool: a patient's genetic information would simply be entered into the model, which would correlate and analyze the data and output an overall probability of stroke, based on the stroke-related SNPs in the patient's genome. "It sounds like magic," says Ramoni. "But it's just a piece of technology. It gives hope that we will be able to predict early on whether someone is at risk of getting stroke, and allow you to convince them to make life changes."

"The next step is to get more SNPs," Ramoni adds. "These analyses looked at only 1,313 out of 3.3 million known SNPs. Even a million SNPs would cover the vast majority of the genome. We would get much better predictions."

Ramoni also says that by identifying all the genetic variants that modulate the risk of stroke, it could provide insight into its mechanisms and provide targets for future drugs. He is currently refining the model and believes that this technology could be used to predict inherited risk of many other conditions.


'/>"/>

Contact: Keri Stedman
keri.stedman@childrens.harvard.edu
617-919-3110
Children's Hospital Boston
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. UBC study establishes formula for predicting climate change impact on salmon stocks
2. Predicting acute GVHD by gene expression could improve liver stem cell transplant outcomes
3. Predicting the distribution of creatures great and small
4. Predicting the perfect predator
5. Predicting the radiation risk to ESAs astronauts
6. Predicting growth hormone treatment success
7. Trial seeks genetic fingerprint for predicting drug effectiveness
8. Researchers identify a cell type that limits stroke damage
9. Statins may treat blood vessel disorder that can lead to fatal strokes
10. Stroke Belt deaths tied to non-traditional risk factors
11. Study helps explain connection between sleep apnea, stroke and death

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2009)...o tobacco smoke and during childhood to lead face ...search done at Cincinnati Children,s Hospital Medi...percent of ADHD cases in children between the ages...of these environmental exposures. This could trans... lead exposure each have their own important adver...
(Date:11/22/2009)...harmaceuticals today announced that its scientists...tated IDH1 gene has a novel enzyme activity consis... breakthrough discovery shows that the mutated for...e (2HG), which may contribute to the formation and... type of brain cancers. This discovery appears to ...
(Date:11/20/2009)...bout the health benefits of having a life partner....ere amino acids known as cysteines are much more v...p with other cysteines. , Now, researchers at th... Belgium, have discovered a new antioxidant system...ars in the Nov. 20 issue of the journal Science ....
Breaking Biology News(10 mins):Exposure to lead, tobacco smoke raises risk of ADHD 2Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer 2Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer 3Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer 4Saving the single cysteine: New antioxidant system found 2United States Patent Office Issues Patent Covering the Approved Administration of Kuvan With Food 6028 1United States Patent Office Issues Patent Covering the Approved Administration of Kuvan With Food 6028 2United States Patent Office Issues Patent Covering the Approved Administration of Kuvan With Food 6028 3United States Patent Office Issues Patent Covering the Approved Administration of Kuvan With Food 6028 4Bionovo Announces Third Quarter 2009 Highlights and Financial Results 6024 1Bionovo Announces Third Quarter 2009 Highlights and Financial Results 6024 2Bionovo Announces Third Quarter 2009 Highlights and Financial Results 6024 3Bionovo Announces Third Quarter 2009 Highlights and Financial Results 6024 4Bionovo Announces Third Quarter 2009 Highlights and Financial Results 6024 5Bionovo Announces Third Quarter 2009 Highlights and Financial Results 6024 6Bionovo Announces Third Quarter 2009 Highlights and Financial Results 6024 7Bionovo Announces Third Quarter 2009 Highlights and Financial Results 6024 8Bionovo Announces Third Quarter 2009 Highlights and Financial Results 6024 9Complete Horse Genome Sequence Revealed 60783 1Complete Horse Genome Sequence Revealed 60783 2
... Minnesota School of Public Health Project Eating ...vidence to support the importance of encouraging y...ned the association between breakfast frequency an...adolescents, and the results indicate that daily b... more physically active than breakfast skippers du...
...29 /Xinhua-PRNewswire/ -- Futronic Technology Comp...re and hardware products,today announced that the ...,software supports Microsoft Vista and Windows 200... software for Microsoft Windows,Logon control usin...By a,finger touch, computer users can logon Window...
...erence Schedule , The following schedule of press...g the Ocean Sciences Meeting. Press conferences ma...ay change, and participants may change. All update...Room (W307D, West Building, Orange County Conventi...ess Room. The times listed below are Eastern Stand...
Other Biology News:U of M finds teens who eat breakfast daily eat healthier diets than those who skip breakfast 2Futronic Announces Microsoft Vista and Windows 2008 Server Support for Its Fingerprint Logon Software 22008 Ocean Sciences Meeting -- media advisory 2 22008 Ocean Sciences Meeting -- media advisory 2 32008 Ocean Sciences Meeting -- media advisory 2 42008 Ocean Sciences Meeting -- media advisory 2 52008 Ocean Sciences Meeting -- media advisory 2 62008 Ocean Sciences Meeting -- media advisory 2 72008 Ocean Sciences Meeting -- media advisory 2 82008 Ocean Sciences Meeting -- media advisory 2 9
(Date:11/19/2009)..., BETHESDA, Md., Nov. 19 ...or in biotechnology for diabetes therapy, and a pr...ices to food, supplement, biotechnology and pharma...previously reported $6.3 million registered direct... shares of its common stock and warrants to purcha...
(Date:11/19/2009)...STER, Germany, November 19 MONITOR...ovember 16th, 2009 Flibanserin in the,indication t...arkinson,s,disease for orphan drug status designat...odopa-induced dyskinesia is a complication of the ...erious burden to some of those,affected, since it ...
(Date:11/19/2009)... InSound is honored by latest award for revolu...wark, CA (PRWEB) November 16, 2009 -- Popular Scie...rdquo; hearing aid from InSound Medical a winner o...e Health category.    Chosen f...side deep in the hearing canal for up to four mont...
(Date:11/18/2009)...nel need to be able to find explosive materials an...id such searches, the National Institute of Standa...epartment of Homeland Security, has developed a ne... Material (SRM) 2905, Trace Particulate Explosives...ds, the SRM will be helpful in calibrating, testin...
Breaking Biology Technology:Spherix Announces the Closing of $6.3 Million Registered Direct Offering 2Spherix Announces the Closing of $6.3 Million Registered Direct Offering 3MONITORING FORCE GmbH Requests Acknowledgment of Flibanserin as "Orphan Drug" 2Popular Science Awards Lyric “Invisible” Hearing Aid 2009 “Best of What's New” Award 2Popular Science Awards Lyric “Invisible” Hearing Aid 2009 “Best of What's New” Award 3New NIST trace explosives standard slated for homeland security duty 2
...ISON, Wis. - The need to rapidly identify biologic...cks has led to the creation of a genome database m...s company that specializes in optical mapping of...cisella tularensis, is a causative agent of Tulare... fever. The bacterium is naturally found in rodent...
...WAUKEE TeraMEDICA , a medical informatics compan...ent Image Manager (TIM) enterprise image managemen...ise archive software solution designed to capture ... communication systems (PACS), store the digital i... point of patient care across the healthcare enter...
...get an idea of the intricacy possible in machining...g: using electro-discharge machining, or EDM, you ...l the metal under the image of Roosevelt, and leav...thin as foil. , ,Its an impressive example used by...a Valley Technical Colleges glass and steel Manuf...
Other Biology Technology:OpGen Database Helps to Reduce Bioterrorist Threat 2Powerful, Intricate Technology Taught in CVTCs New Tool and Die Program 2Powerful, Intricate Technology Taught in CVTCs New Tool and Die Program 3
5X Competitor II (Mouse) from Takara Mirus Bio
Goat Anti-Mouse Ig + IgM Antibody, FITC Conjugated from Cayman Chemical
MoDC Differentiation Kit from 3H Biomedical AB
Frozen Tissue Section Panel - Monkey (Cynomolgus) Normal Tissue, Multi-tissue III from BioChain
Biology Products: