Navigation Links
Powerful yet reliable proteomics techniques are the focus of a new methods book
Date:2/15/2008

COLD SPRING HARBOR, N.Y. Conventional approaches to proteomics have recently been augmented with a new generation of technologies unfamiliar to many life science researchers. A new methods book, Proteomics: Methods Express, identifies the most powerful of these new technologies and presents them in a way that allows their robust implementation in even non-specialist labs.

Proteomics: Methods Express is an essential, comprehensive laboratory manual and research guide for scientists in all biomedical fields and at all levels, from postgraduate student to principal investigator. It is published by Scion Publishing Ltd. (www.scionpublishing.com) and distributed in the United States, Canada, and South America by Cold Spring Harbor Laboratory Press (www.cshlpress.com).

The vast molecular diversity of proteins has triggered the development of a proportionately large number of proteomic approaches, write the editors, C. David OConnor and B. David Hames, in the Preface to the book. [I]t confuses novices, who need a core set of reliable protocols that are relatively painless to implement but sufficiently powerful to yield valuable new scientific information. This book provides such a set of procedures.

The chapters are presented in the order in which the methods are performed, starting with sample preparation and isotope-labeling. The next chapters present standard separation methods for proteins, peptides, and protein complexes, including gel electrophoresis, chromatography, and mass spectrometry. These are followed by chapters on modern, innovative procedures such as DESI (desorption electrospray ionization) and protein microarrays, as well as clinical applications for proteomic profiling and the analysis of post-translational modifications. The final chapters discuss bioinformatic-based approaches for handling the enormous amounts of data that are produced during such studies.

Each chapter includes a discussion of the merits and limitations of various approaches and then provides selected protocols with useful hints and tips for successand troubleshooting for when things go wrong. They include descriptions of what can, and currently cannot, be achieved with the relevant procedures so that readers can make informed judgments prior to establishing the methods in-house.


'/>"/>

Contact: Jane Carter
jane.carter@scionpublishing.com
516-422-4071
Cold Spring Harbor Laboratory
Source:Eurekalert  

Related biology news :

1. Gene discovery made easier with powerful new networking technique
2. There is powerful evidence of evolution in human DNA
3. Blood pressure drug telmisartan shows powerful activity against stroke
4. In the laboratory, green tea proves a powerful medicine against severe sepsis
5. Powerful integration of lipid metabolic profiling with gene expression analysis
6. Enzyme alerts cells powerful army to repair DNA damage
7. The power of multiples: Connecting wind farms can make a more reliable - and cheaper - power source
8. Stowers Proteomics Center devises method for assigning probabilities to human protein interactions
9. Story ideas from Molecular & Cellular Proteomics
10. New techniques create butanol
11. Software Techniques Inc. Selects M2SYS Fingerprint Software to Meet Continuous Growth and Demand for Desktop Biometric Time & Attendance Solutions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Powerful yet reliable proteomics techniques are the focus of a new methods book
(Date:5/12/2016)... WearablesResearch.com , a brand of Troubadour ... from the Q1 wave of its quarterly wearables survey. ... receptivity to a program where they would receive discounts ... company. "We were surprised to see that ... LaColla , CEO of Troubadour Research, "primarily because there ...
(Date:4/28/2016)... 2016 First quarter 2016:   ... with the first quarter of 2015 The gross margin ... (loss: 18.8) and the operating margin was 40% (-13) ... Cash flow from operations was SEK 249.9 M (21.2) , ... unchanged, SEK 7,000-8,500 M. The operating margin for 2016 ...
(Date:4/15/2016)...  A new partnership announced today will help ... in a fraction of the time it takes ... life insurance policies to consumers without requiring inconvenient ... Diagnostics, rapid testing (A1C, Cotinine and HIV) and ... weight, pulse, BMI, and activity data) available at ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... today announced the launch of the Supplyframe Design Lab . Located in ... to explore the future of how hardware projects are designed, built and brought ...
(Date:6/23/2016)... ... ... In a new case report published today in STEM CELLS Translational Medicine, doctors ... being treated for breast cancer benefitted from an injection of stem cells derived from ... frequent side effect of cancer treatment. , Lymphedema refers to the swelling ...
(Date:6/23/2016)...  Blueprint Bio, a company dedicated to identifying, protecting ... has closed its Series A funding round, according to ... "We have received a commitment from Forentis Fund that ... meet our current goals," stated Matthew Nunez . ... complete validation on the current projects in our pipeline, ...
(Date:6/23/2016)... , June 23, 2016 On ... session at 4,833.32, down 0.22%; the Dow Jones Industrial Average ... 500 closed at 2,085.45, down 0.17%. Stock-Callers.com has initiated coverage ... INFI ), Nektar Therapeutics (NASDAQ: NKTR ), Aralez ... Inc. (NASDAQ: BIND ). Learn more about these ...
Breaking Biology Technology: