Navigation Links
Poultry probiotic's coat clues to ability to battle bugs
Date:11/18/2013

IFR researchers have characterised the coat of a potential poultry probiotic, giving the first clues of how it may be used to exclude pathogenic bacteria from chickens.

Lactobacillus johnsonii has previously been shown to exclude Clostridium perfringens from the guts of poultry, opening the door to it being developed as a way of reducing necrotic enteritis in poultry and food poisoning in humans. Recently, researchers at the Institute of Food Research, which is strategically supported by the Biotechnology and Biological Sciences Research Council, found that the bacteria make coats for themselves that play important roles in colonisation in this strain.

Now, in a study published in The Journal of Biological Chemistry, the researchers present the first characterisation of what makes up this coat. This will give us a better idea of the role of the coat and help in the development of these bacteria as a way of combatting C. perfringens.

Using NMR spectroscopy, the researchers discovered that the coat is made up of two types of exopolysaccharides (EPS), which are long sugar-containing molecules that many bacteria use to encapsulate themselves. This capsule may help the bacteria to cope with environmental stress, or aid colonisation and adhesion. Different bacterial strains have different EPS structures, and understanding this is important as they represent a key way bacteria interact with the world around them.

'Characterising the EPS structures in the L. johnsonii strain is the first step to explaining how it might outcompete C. perfringens.' said Dr Arjan Narbad.

Previous studies had identified potential genes in L. johnsonii for producing EPS, giving the researchers tools to probe how the bacteria synthesise these molecules. Knocking out the whole cluster of EPS genes meant the bacteria produced no capsule. Further analysis of the genes by IFR PhD student Enes Dertli uncovered their poten
'/>"/>

Contact: Andrew Chapple
andrew.chapple@ifr.ac.uk
44-016-032-514-590
Norwich BioScience Institutes
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Investigators link poultry contamination on farm and at processing plant
2. Bird flu in live poultry markets are the source of viruses causing human infections
3. Appetite genes are key to better diets for poultry, study shows
4. Promoting poultry health through diet
5. £12 million funding to tackle devastating livestock and poultry viruses
6. Probiotics may add functionality to fruit juices
7. Study finds taking probiotics has benefits for patients in hospitals
8. Probiotics found to reduce hepatic encephalopathy
9. Study: Probiotics reduce stress-induced intestinal flare-ups
10. New study shows probiotics help fish grow up faster and healthier
11. Behind closed doors: Researchers show how probiotics boost plant immunity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Poultry probiotic's coat clues to ability to battle bugs
(Date:4/23/2014)... of dementia and affects some 400,000 people in Spain ... One of the reasons for this is the lack ... in nerve transmissions and the loss of memory in ... Institute of Neuroscience at the Universitat Autnoma de Barcelona ... and were able to develop a gene therapy which ...
(Date:4/23/2014)... of social relationships they may be friends, kin, ... From a cognitive perspective, understanding one,s own relationships to ... ("knowing who is nice or not"). Yet, understanding also ... the stage for "political" maneuvers ("knowing who might support ... in the scientific journal Nature Communications . ...
(Date:4/23/2014)... London (April 23, 2014). "I think one can argue that ... well as doing everything else that we canthen we can ... Wigley, one of the world,s foremost climate researchers, in the ... published by SAGE. Refusing to take significant action on climate ... be needed to address the problem, Wigley explains in an ...
Breaking Biology News(10 mins):Loss of memory in Alzheimer's mice models reversed through gene therapy 2Ravens understand the relations among others 2Is nuclear power the only way to avoid geoengineering? 2
... different from what a runner might take on a ... to make life more comfortable for cattle. A ... a pedometer are a few of the tools K-State ... two routine procedures, castration and dehorning. Hans Coetzee, ...
... including nursery and greenhouse producers, landscape services firms, ... during the past two decades, becoming an increasingly ... the Green Industry generated 1.96 million jobs and ... U.S. nursery and greenhouse crops reached $16.9 billion. ...
... the twelfth release in a series of erect-growing, ... Watson) cultivars developed by the University of Arkansas. ... of the Department of Horticulture at the University ... issue of the American Society of Horticultural Science,s ...
Cached Biology News:Veterinarians developing model to help producers, vets make cattle more comfortable 2Veterinarians developing model to help producers, vets make cattle more comfortable 3Results of national nursery survey unveiled 2
(Date:1/15/2014)... IL (PRWEB) January 15, 2014 Look ... find hard-working items for the lab, from fluid handling ... Guaranteed-in-Stock (GIS)—ready to ship when you order. , ... Peristaltic Pumps , from the L/S® model for precise ...
(Date:1/15/2014)... OXFORD, England and SAN JOSE, California ... an international biotechnology company developing antibody-drug conjugates for cancer, today ... its Board of Directors. Dr Reynolds has over 20 years, ... Chief Medical Officer at Seattle Genetics. "I am ...
(Date:1/15/2014)... This webinar will focus on EMA and ... in biosimilars. , Regulatory frameworks are evolving many countries ... the complex nature of biopharmaceuticals makes the demonstration of ... challenging. Based on the specific aspects of biosimilar drug ...
(Date:1/15/2014)... More than 5 million Americans are ... 3 seniors will die with Alzheimer’s or another dementia, ... have shocked many Americans into looking for ways to ... tragic age-related cognitive disorders. Jonathan Weisman, president of Biohack ...
Breaking Biology Technology:Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2
... Technologies , a high-technology spin-off of the University of ... during the biggest blackout the nation has ever seen. ... Near-simultaneous events were recorded in New York and Michigan ... across the northeastern United States, with the I-Grid recording ...
... Wisconsin companies recently won CIO magazines CIO ... resourcefulness regarding the use of information technology(IT) within their ... Menasha Corp. each won the award, announced in the ... Manpower CIOs are on the cover of the magazine. ...
... a two-year grant from the state Department of Commerce ... which for years trailed their counterparts in Madison in ... up. Thats good news for Milwaukee - which means ... wants to transform itself from an old-line manufacturing burg ...
Cached Biology Technology:Local Company Records Blackout with Web-Based Monitoring System 2Local Company Records Blackout with Web-Based Monitoring System 3Five Wisconsin Non-Tech Companies Win IT Awards 2Five Wisconsin Non-Tech Companies Win IT Awards 3Five Wisconsin Non-Tech Companies Win IT Awards 4Milwaukee research institutions step up the pace for technology transfer 2
... clone d1-174 GenBank Accession Number : ... N-terminal tagged fusion protein corresponding to full ... Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium ... 30% Quality Assurance: routinely evaluated by immunoblot ...
...
X-Gal, 1 g. 5-Bromo-4-chloro-3-indolyl-b-d-galactoside.Histochemical substrate for b-galactosidase, used in blue/white screening.Store at -20 C. Protect from moisture. Category: Nucleotides & Enzymes...
Conjugation services for Antibodies, Proteins, Oligos, Peptides, Beads, bioconjugation, antibody-oligonucleotide, LNA peptide, LNA protein, LNA antibody, HRP, Alkaline phosphatase, phycoerythrin, FIT...
Biology Products: