Navigation Links
Potential new HIV drug may help patients not responding to treatment
Date:3/31/2009

A potential treatment for HIV may one day help people who are not responding to Anti-Retroviral Therapy, suggests new research published tomorrow in The Journal of Immunology. Scientists looking at monkeys with the simian form of HIV were able to reduce the virus levels in the blood to undetectable levels, by treating the monkeys with a molecule called D-1mT alongside Anti-Retroviral Therapy (ART).

Simian Immunodeficiency Virus (SIV) is very similar to Human Immunodeficiency Virus (HIV) and it is used to study the condition in animal models. In both HIV and SIV, the level of virus in the blood, or 'viral load', is important because when the viral load is high, the disease progresses and it depletes the patient's immune system. This eventually leads to the onset of Acquired Immune Deficiency Syndrome (AIDS), where the patient cannot fight infections which would be innocuous in healthy individuals.

Currently, the 'gold standard' treatment for HIV is Highly Active Anti-Retroviral Therapy (HAART), a cocktail of drugs that reduces the viral load by stopping the virus from replicating. HAART can increase the life expectancy of an HIV-positive patient substantially if it works well. However, the treatment is not effective for around one in ten patients, partly because some develop resistance to the drugs used in HAART. The researchers, from Imperial College London, the National Cancer Institute, Bethesda, and Innsbruck Medical University, hope their study could ultimately lead to a new treatment that will help HAART to work more effectively in these people.

In the new study, researchers gave daily doses of a modified amino acid called D-1mT to 11 rhesus macaques infected with SIV. All of the macaques had been treated with ART for at least four months. Eight of the macaques had higher viral loads (reaching up to 100,000 copies of the virus per millilitre of blood), because they were not responding completely to the treatment. However,
'/>"/>

Contact: Lucy Goodchild
lucy.goodchild@imperial.ac.uk
44-020-759-46702
Imperial College London
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Pittsburgh scientists identify human source of stem cells with potential to repair muscle
2. Neuronal conduction of excitation without action potentials based on ceramide production
3. To maximize biofuel potential, researchers look for sorghums sweet spot
4. Joslin researchers uncover potential role of leptin in diabetes
5. Chemistry turns killer gas into potential cure
6. Researchers examine worlds potential to produce biodiesel
7. New inhibitor has potential as cancer drug
8. Potential new therapeutic molecular target to fight cancer
9. WCS study finds potential to double tiger numbers in South Asia
10. Childrens Hospital studying drug with the potential to prevent/delay onset of type 1 diabetes
11. Great potential to improve collection, recycling of Europes electronic waste, says UN report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2015)... , February 11, 2015 ... research report "Access Control Market by Product (Cards and ... Residential, Military and Defense, Government, Industrial, Healthcare, Education) and ... published by MarketsandMarkets, the Access Control Market ... 2020, growing at a CAGR of 10.6% ...
(Date:2/5/2015)... , 5. Februar 2015 ... spezialisiertes Logistikunternehmen und hat eine neue Marketingkampagne ... Logistikfirma (Clinical Logistics Organization – CLO) der ... Kampagne lautet First , mit Schwerpunkt ... Foto: http://photos.prnewswire.com/prnh/20150205/173753 Logo ...
(Date:2/5/2015)... , Jan. 26, 2015 NXT-ID, Inc. (NASDAQ: ... a biometric authentication company focused on the growing mobile ... website ( http://www.nxt-id.com/ ) as part of its 2015 ... The Company launched its new consumer website for Wocketwallet.com ... , CEO of NXT-ID said, "Our new corporate website ...
Breaking Biology News(10 mins):Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 2NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 3
... from the Florida Everglades can withstand exposure to salt ... ocean and estuarine environments, according to research in the ... Biology and Ecology . This recent study, based ... Geological Survey, provides initial evidence that pythons ...
... CALIF (Jan 4, 2012) Daily doses of ... improved menopausal symptoms, including significantly reducing hot flash ... study in postmenopausal Japanese women published in the ... "It is believed that S-equol, produced from ...
... Therapeutic hypothermia has been proven to reduce mortality and ... was rarely used in a sample of more than ... Hypothermia and Temperature Management, a peer-reviewed journal published by ... www.liebertpub.com/ther Therapeutic hyperthermia was used in ...
Cached Biology News:Salt water alone unlikely to halt Burmese python invasion 2New fermented soy ingredient containing S-equol significantly reduced hot flash frequency 2New fermented soy ingredient containing S-equol significantly reduced hot flash frequency 3New fermented soy ingredient containing S-equol significantly reduced hot flash frequency 4New fermented soy ingredient containing S-equol significantly reduced hot flash frequency 5
(Date:3/3/2015)... NASA astronaut Scott Kelly , who is making final ... living and working on the International Space Station, will be ... EDT Monday, March 9. Kelly will participate from ... weeks of his training. The interviews will be preceded at ... mission training and previous spaceflights. To schedule an ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 Experts and ... schedules for one event: the Alltech REBELation exploring innovation, ... May 17-20. Now in its 31st year, Alltech’s annual ... 70 countries, and the opportunity to join the REBELation ... 7 at 11:59 p.m. EST, at which point the ...
(Date:3/3/2015)... Inc. (TSXV: BRM) ("Biorem" or "the Company") today announced several new ... in North America , the Middle ... "Bidding activity in 2015 continues to be robust" said Derek ... for bidding in 2014, we are pleased to see the bidding ... organization,s renewed focus on select market segments where we can add ...
(Date:3/3/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/rcv4lq/gene_therapy ... Therapy Market, 2015 - 2025" report to their ... report provides an extensive study on the marketed and ... carried out in this field for over a decade ... in Asian markets; one approved in the EU). There ...
Breaking Biology Technology:NASA Astronaut Scott Kelly Available for Interviews before One-Year Space Station Mission 2World-renowned Leaders, Authors and Businesspeople Join the Alltech REBELation 2World-renowned Leaders, Authors and Businesspeople Join the Alltech REBELation 3World-renowned Leaders, Authors and Businesspeople Join the Alltech REBELation 4Global Gene Therapy Market Report 2015-2025 - Extensive Study on the Marketed and Pipeline Gene Therapies 2Global Gene Therapy Market Report 2015-2025 - Extensive Study on the Marketed and Pipeline Gene Therapies 3Global Gene Therapy Market Report 2015-2025 - Extensive Study on the Marketed and Pipeline Gene Therapies 4Global Gene Therapy Market Report 2015-2025 - Extensive Study on the Marketed and Pipeline Gene Therapies 5Global Gene Therapy Market Report 2015-2025 - Extensive Study on the Marketed and Pipeline Gene Therapies 6Global Gene Therapy Market Report 2015-2025 - Extensive Study on the Marketed and Pipeline Gene Therapies 7
... John Reed with Fair Political,Practices Commission, SANTA MONICA, ... C. Reed, must resign from the board for,violating conflict ... (FTCR) said today., Reed intervened and attempted to ... affiliated with the Burnham Institute, where Reed is,president and ...
... ALTO, Calif., Nov. 21 Alexza,Pharmaceuticals, Inc. (Nasdaq: ... will be webcast live during the 19th Annual ... 2007 at 2:30 p.m. Eastern,Time. The presentation will ... and,may be accessed under the Investor Relations tab ...
... ViroPharma Incorporated,(Nasdaq: VPHM ) today announced that ... officer of ViroPharma, will present,at the Lazard Capital ... on Tuesday, November 27, 2007. The conference is ... ViroPharma also announced that Michel de Rosen, president ...
Cached Biology Technology:California Stem Cell Board Member Violates Conflict Rules; Should Resign From Committee, Consumer Group Says 2California Stem Cell Board Member Violates Conflict Rules; Should Resign From Committee, Consumer Group Says 319th Annual Piper Jaffray Health Care Conference to Webcast Alexza's Corporate Presentation 2ViroPharma to Present at Two Upcoming Healthcare Conferences 2
X-Gal, 1 g. 5-Bromo-4-chloro-3-indolyl-b-d-galactoside.Histochemical substrate for b-galactosidase, used in blue/white screening.Store at -20 C. Protect from moisture. Category: Nucleotides & Enzymes...
Conjugation services for Antibodies, Proteins, Oligos, Peptides, Beads, bioconjugation, antibody-oligonucleotide, LNA peptide, LNA protein, LNA antibody, HRP, Alkaline phosphatase, phycoerythrin, FIT...
FGF Receptor 1 Antibody...
Mouse Galectin-1 Affinity Purified Polyclonal Ab...
Biology Products: