Navigation Links
Post heart attack recovery may not be aided by stem cell injections, but trial demonstrates promise
Date:11/14/2011

CLEVELAND/ORLANDO University Hospitals Case Medical Center researchers could still be close to giving heart attack patients a second chancejust not as they originally thought.

LateTIME was a study of adult stem cells (autologous) harnessed from bone marrow that were believed to have the ability to improve heart function after an attack if injected into the heart within two weeks of the attack. Results are being released today at American Heart Association Scientific Sessions and published this week in Journal of the American Medical Association (JAMA).

The results have shown the injections within that timeframe were not favorable, but the concept showed great promise, according to an accompanying JAMA editorial that assessed the trial.

The therapy still shows promise for recovering lost or damaged heart tissue resulting from a heart attack. Both UH Case Medical Center's Drs. Dan Simon and Marco Costa, co-investigators in the LateTIME study, are currently participating in a similar trial, "TIME" that already has reduced the time between attack and stem cell injection.

The pair is optimistic the time variable adjustment in the new trial will lend favorable outcomes. Dr. Simon is Chief, Cardiovascular Medicine at UH Case Medical Center and the Herman K. Hellerstein Professor of Cardiovascular Research, Case Western Reserve School of Medicine. Dr. Costa is the director of the Interventional Cardiovascular Center and Research & Innovation Center at UH Case Medical Center as well as a professor of medicine at Case Western Reserve University School of Medicine.

The shared theories in both trials is that the specialized cells could have the ability to promote blood vessel growth, prevent cell death and transform themselves into a number of tissues, including muscle. After an acute heart attack, a remodeling process was initiated in the heart in an attempt to compensate for the damaged areas.

Researchers surmised th
'/>"/>

Contact: Mike Ferrari
mike.ferrari@uhhospitals.org
440-478-4563
University Hospitals Case Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Results triple researchers projections with use of adult stem cells for heart failure
2. Low vitamin C levels may raise heart failure patients risk
3. Diseased hearts to heal themselves in future
4. Biologists use flies and mice to get to the heart of Down syndrome
5. Targeting leg fatigue in heart failure
6. Fatty acids involved in python heart growth could benefit diseased human heart
7. UM School of Medicine finds new pathway critical to heart arrhythmia
8. New study finds fetal heart rate not a good indicator of a babys health
9. Womens heart disease tied to small blood vessels
10. Einstein College of Medicine given $6.7 million to study congenital heart defect genetics
11. WPI mathematics professor Dalin Tang elected a Fellow of the American Heart Association
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 11, 2014 The increased risk of kidney injury ... resuscitation fluids reflects the mass of HES molecules, according ... official journal of the International Anesthesia Research Society (IARS). ... harmful effect of HES on cultured human renal proximal ... Christian Wunder and colleagues of University Hospital Wrzburg, Austria. ...
(Date:7/11/2014)... exists that cannabinoid receptor type 1 can ... influx, and reduce neurotransmitter release. However, some ... can increase extracellular Ca2+ influx and increase ... team, Tongji Hospital Affiliated to Tongji Medical ... China used whole cell voltage-clamp and calcium ...
(Date:7/10/2014)... Albuquerque, and other major cities in New Mexico, nearly ... municipal wastewater rather than precious potable water supplies. Across ... of all golf courses receive treated effluent. Reusing the ... Additionally, golf courses and homeowners alike fertilize their lawns ... is nitrate. A New Mexico State University turfgrass expert ...
Breaking Biology News(10 mins):In lab studies, hydroxyethyl starch has direct harmful effects on kidney cells 2'Tailored' water -- the latest in lawn care 2
... a person's under stress or injured, the adrenal gland ... normal. But the hormone's effects are many and varied, ... memories with short-term exposure, while impairing learning if there's ... its effects,understanding how cortisol is made is essential to ...
... has emerged as a promising alternative for ... and tissues, circumventing the complications associated with ... or regenerate damaged tissue by using engineered ... regeneration and eventually integrate into the host ...
... and rheumatoid arthritis occur when the immune system fails ... where the molecular breakdowns responsible for such failures occur. ... and the Dana-Farber Cancer Institute have identified a key ... autoimmune disease, findings that may help scientists develop new ...
Cached Biology News:Scientists unravel clue in cortisol production 2Cracking open the black box of autoimmune disease 2
(Date:7/11/2014)... Cayenne Medical, Inc., a privately ... soft tissue reconstruction segment, announced the worldwide launch ... involving the shoulder and extremities. The SureLock System ... deployment method. The unique delivery eliminates manual tensioning ... or anchor displacement (also commonly know as anchor ...
(Date:7/10/2014)... 2014 Terascala, the industry leader in ... Swahn, a former vice president of product management for ... president of marketing. Terascala’s software when combined with leading ... the highest performance and most reliable solutions for processing ... Terascala’s channel expansion and broaden its product portfolio. His ...
(Date:7/10/2014)... CA (PRWEB) July 10, 2014 Senior ... institutions and professional associations, addressed the challenges of “Reducing ... Medical Device Industries” through strategic sourcing. Describing the partnership ... with the Supply Chain Management Institute ( SCMI) ... event on June 24 at the Kroc Institute of ...
(Date:7/10/2014)... , July 10, 2014 Research and ... of the "International Photonic Integrated Circuit (Monolithic ... to 2019" report to their offering. ... The concept of photonic integration traces its roots ... The promise of photonic integration went unexplored and ...
Breaking Biology Technology:Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 3Terascala Expands Executive Team 2Terascala Expands Executive Team 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2
... Scott Karasinski, PharmD to Run Medical Services Department of ... Expanding Independent Medical Education Agency, ... the appointment of Scott Karasinski, PharmD to the,position of ... as Director in the Medical Affairs and Drug Information,department ...
... Inc., the leading,systems biology tools company, announced today ... and have added additional capability. This,will provide GSK ... access to MetaCore, MapEditor and MetaBase. MetaCore is,GeneGo,s ... data,featuring a comprehensive collection of pathway maps and ...
... at BIO CEO & Investor Conference, LOUISVILLE, Colo., Feb. ... it will host a conference call on,Tuesday, February 26, 2008 ... earnings. Additionally, Replidyne will present at an upcoming,investor conference in ... follows:, Kenneth J. Collins, President and CEO, ...
Cached Biology Technology:L&M Healthcare Communications, LLC, Hires Scott Karasinski, PharmD 2GSK Extends GeneGo License and Adds New Products 2Replidyne to Report 2007 Fourth Quarter and Year-End Earnings 2Replidyne to Report 2007 Fourth Quarter and Year-End Earnings 3
... scientists developed the Easy-Titer Human IgM Assay ... simple, sensitive, and easy-to-perform assay for Human ... ELISA. This kit incorporates a simple mix-and-read ... IgM concentration from 15-500 ng/ml in approximately ...
... clarification reagent; Ideal for clarifying many ... proteins, nucleic acids, & proteoglycans; Contains ... improves downstream processing; Utilizes a reagent ... supplied as a suspension in saline; ...
A simple, sensitive and reliable method for determining free sulfhydryl content in peptides, protein...
... true benchtop incubator-shaker, has the smallest footprint of ... of 540 x 680 mm (W x D) ... x 505 x 510mm). Available in 25 mm ... ideal for shaking applications requiring controlled speed and ...
Biology Products: