Navigation Links
Possible treatment for kidney disease in lupus studied at UH
Date:5/4/2014

HOUSTON, May 5, 2014 In the U.S. alone, more than 1.5 million people have lupus, a chronic autoimmune disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs. The symptoms can range from debilitating pain and fatigue to organ failure.

One of the most common organs to be attacked by lupus is the kidney, manifesting in lupus nephritis. An estimated 40 percent of lupus patients develop this condition, which causes inflammation of the kidneys, impairing their ability to get rid of waste products and other toxins from the body effectively. Lupus nephritis is the leading cause of lupus-related deaths and results in tens of thousands of hospitalizations per year.

Dr. Chandra Mohan, a biomedical engineer at the University of Houston (UH), has a theory about the development of lupus nephritis and, if he's right, there may already be a treatment. Mohan was recently awarded a $200,000 grant from the Alliance for Lupus Research (ALR), the world's largest funder of lupus research, to study whether the interaction of three specific molecules is the cause of lupus nephritis. Through this grant, Mohan aims to understand to what extent this molecular pathway is activated in lupus and whether it can be therapeutically targeted using specific drugs.

"Currently, management of lupus involves the use of nonspecific drugs, such as steroids, that suppress the immune system. Our lab, however, is trying to find out the exact molecular mechanisms that lead to lupus," Mohan said. "These mechanisms belong to two classes. On the one hand, you have molecules and pathways that activate the immune system to attack your own body cells. The second set of molecules focus on the kidneys once the immune system is activated by lupus. Our present research and grant focuses on this second molecular cascade, and we want to see whether we can target the kidneys to offer therapeutics that lessen the chance of a patient
'/>"/>

Contact: Lisa Merkl
lkmerkl@uh.edu
713-743-8192
University of Houston
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. University of Houston study shows BP oil spill hurt marshes, but recovery possible
2. Researcher who identifed genetic cause and possible treatment for Marfan syndrome honored
3. New York University scientists discover possible treatment to reduce scarring
4. UCLA research makes possible rapid assessment of plant drought tolerance
5. Selfish DNA in animal mitochondria offers possible tool to study aging
6. Is long-term weight loss possible after menopause?
7. African research identifies strong candidate for possible single-dose malaria cure
8. Controlling gait of horses may be possible, says key study from Texas A&M
9. Weber State Scientists discover possible building blocks of ancient genetic systems
10. Estrogenic plants linked to altered hormones, possible behavior changes in monkeys
11. Possible new treatment for Ewing sarcoma
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Possible treatment for kidney disease in lupus studied at UH
(Date:12/11/2014)... PAUL, Minn. , Dec. 10, 2014 /PRNewswire/ ... wireless physiologic monitoring, has released a new series ... needs of preclinical toxicology researchers. M series, part ... help toxicologists collect the best possible physiologic data ... Adding functional endpoints to toxicology studies ...
(Date:12/10/2014)... , Dec. 08, 2014 Research and ... the addition of the "Biometrics Market in ... http://photos.prnewswire.com/prnh/20130307/600769 ... projects such as rural banking and upgradation of ... trends witnessed in the market. Besides the aforementioned ...
(Date:12/3/2014)... Calif. , Dec. 2, 2014   ... globally deployed, innovative test solutions for military, aerospace, ... newest version of its successful TS-900 PXI ... performance and features of high-end systems to customers ... outstanding value compared to traditional ATE. ...
Breaking Biology News(10 mins):New telemetry implants expected to change how large animal toxicology studies are conducted 2Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3
... many farmers have found that the brutal combination of high ... yields looking less like the good or the bad and ... University plant pathologist is finding in a statewide study, Kansas ... opponent: viruses. "We,re still analyzing samples, but it,s turning ...
... A new genetic study by a team of Cuban ... with wild populations of critically endangered Cuban crocodiles, which ... only in the Cuban Archipelago. , Cuban crocodiles ... captivity and were suspected to hybridize in the wild. ...
... Elsevier, world-leading provider of scientific, technical and medical information ... (ADSA) announce the winners of the first annual ... Papers published in JDS throughout 2008 were eligible and ... were taken into consideration. Awards are being conferred in ...
Cached Biology News:Plant pathologist finding Kansas wheat fields a molecular battleground this season 2Study: Wild Cuban crocodiles hybridize with American crocs 2Elsevier and ADSA announce winners of first annual Journal of Dairy Science Most Cited Awards 2Elsevier and ADSA announce winners of first annual Journal of Dairy Science Most Cited Awards 3
(Date:12/19/2014)... In contrast to traditional LED lights where ... Valoya uses proprietary LED technology to incorporate their spectra ... which is critical in low proximity installations. The Valoya ... its lifetime which is up to four times longer ... investment cost was clearly higher when compared to traditional ...
(Date:12/19/2014)... Dec. 18, 2014  Decision Resources Group finds that ... market will grow moderately through 2023 as the aging ... awareness of dental biomaterials all spur procedure volumes. Growth ... China and India ... procedures within reach for a larger proportion of the ...
(Date:12/19/2014)... NEW YORK , Dec. 18, 2014 ... novel therapies for the treatment of chronic pain, announced ... held today. "This was a transformational year ... a promising future for our company," said Sergio ... past year, we have executed on key financial, human ...
(Date:12/17/2014)... “Never say, ‘I cannot do ... Department of Physics, advises young women pursuing careers ... SPIE Women in Optics 18-month planner ... ask questions.” , In the annual planner, women ... ranging from university professor and laboratory researcher to ...
Breaking Biology Technology:Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 3Relmada Therapeutics Announces Results of Annual Shareholders Meeting 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 3
... England, October 9 /PRNewswire-FirstCall/,-- Evotec AG (Frankfurt Stock Exchange: ... on Tuesday 16 October 2007 at 13.00 pm BST ... will be broadcast live on the internet. Jorn ... (Chief,Research & Development Officer) and Dr Tim Tasker, (EVP ...
... Save Time and Money, OAK BROOK, ... The University,HealthSystem Consortium (UHC), an alliance of ... SciQuest, a provider of e-procurement,technology and services ... partnership to provide organizations participating in,UHC,s new ...
... Affairs and Vice President of ... Pharmaceutical Science, SAN ... biopharmaceutical company focused on developing novel,pain management therapies, announced today the ... Russell Kawahata, Ph.D. as,the Vice President of Pharmaceutical Science. Anthony ...
Cached Biology Technology:Evotec AG: R&D Update on 16 October 2007 Live on the Internet 2University HealthSystem Consortium Chooses SciQuest to Optimize Medical Research Procurement 2University HealthSystem Consortium Chooses SciQuest to Optimize Medical Research Procurement 3NeurogesX Expands Senior Management Team 2NeurogesX Expands Senior Management Team 3
... Precision-designed for Optimal Microdissection , CapSure ... the precise and rapid extraction of populations ... cytology samples with Laser Capture Microdissection., ... Downstream Molecular Analysis , All CapSure LCM ...
... new MyiQ real-time PCR detection system offers ... common green fluorescent dyes such as FAM ... directly with the iCycler thermal cycler, offering ... Peltier-effect driven performance. The MyiQ real-time PCR ...
... is the method of choice for thousands ... only instrument to offer both LCM and ... UV Laser Cutting provides unprecedented speed ... capturing large numbers of cells. , ...
... Simultaneously perform 96 assays on one ... one microarray plate with 96 (7mm x ... protein, gene expression, or screening analysis studies. ... compression fit gasket, eliminating the presence of ...
Biology Products: