Navigation Links
Possible new treatment for Ewing sarcoma
Date:11/26/2012

roperties in several different cancers, including acute leukemias, breast and prostate cancers," Sharma said.

"After Steve showed that LSD-1 was directly regulating the function of EWS/FLI, we teamed up with him to see whether the LSD inhibitors we had discovered worked in Ewing sarcoma models," Sharma said. "Our tests in Ewing sarcoma tissue cultures show they are extremely potent."

Lessnick and Sharma are now working together to further test LSD inhibitors in animal models as they work toward approval of a first-in-man clinical trial. In addition, Lessnick's basic science research on LSD-1 in Ewing sarcoma continues. "We think it may play a larger role in Ewing sarcoma than simply turning off a handful of genes, and we're looking into that," said Lessnick.

"This is a great example of how collaboration between the therapeutics and basic science programs can lead to new treatments for patientsone of HCI's highest goals," said Sharma.


'/>"/>

Contact: Linda Aagard
801-587-7639
University of Utah Health Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. University of Houston study shows BP oil spill hurt marshes, but recovery possible
2. Researcher who identifed genetic cause and possible treatment for Marfan syndrome honored
3. New York University scientists discover possible treatment to reduce scarring
4. UCLA research makes possible rapid assessment of plant drought tolerance
5. Selfish DNA in animal mitochondria offers possible tool to study aging
6. Is long-term weight loss possible after menopause?
7. African research identifies strong candidate for possible single-dose malaria cure
8. Controlling gait of horses may be possible, says key study from Texas A&M
9. Weber State Scientists discover possible building blocks of ancient genetic systems
10. Estrogenic plants linked to altered hormones, possible behavior changes in monkeys
11. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2015)... Mar. 26, 2015 Research and Markets ... "Global Gesture Recognition Market in Automotive Sector 2014-2018" ... forecast the Global Gesture Recognition market in Automotive Sector ... period 2013-2018. Gesture recognition is the ability ... gestures of an individual. Gesture recognition technology can be ...
(Date:3/24/2015)... 24, 2015 Research and Markets ( ... "Global Iris Recognition Market 2015-2019" report to their ... Recognition market to grow at a CAGR of 23.5 ... covers the present scenario and the growth prospects of ... To calculate the market size, the report considers the ...
(Date:3/24/2015)... --  NexID Biometrics LLC, whose spoof-mitigation technology boosts ... the beginning of shipments of version 2.0 of its ... based in Potsdam, N.Y. , is ... began here today at the Walter E. Washington Convention ... SDK boosts the accuracy rate range to 96.5 to ...
Breaking Biology News(10 mins):Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2
... medical information beyond what current newborn screening already provides? ... funded by the Eunice Kennedy Shriver National Institute of ... Human Genome Research Institute (NHGRI), both parts of the ... four grantees have been made in fiscal year 2013 ...
... a polyphenolic compound, is synthesized in several plants ... anti-inflammatory and anti-carcinogenic properties. Resveratrol exhibits neuroprotective effects ... ischemia, Huntington,s disease, Parkinson,s disease and Alzheimer,s disease. ... the effect of resveratrol in vascular dementia. Dr ...
... September 4, 2013 A study published today ... tool to accurately analyze extremely rare mitochondrial DNA (mtDNA) ... as well as aging. This approach, which relies on ... researchers explore mtDNA deletions as potential disease biomarkers. ...
Cached Biology News:NIH program explores the use of genomic sequencing in newborn healthcare 2NIH program explores the use of genomic sequencing in newborn healthcare 3NIH program explores the use of genomic sequencing in newborn healthcare 4Extremely rare mitochondrial DNA deletions associated with aging can be accurately detected with Droplet Digital PCR 2Extremely rare mitochondrial DNA deletions associated with aging can be accurately detected with Droplet Digital PCR 3
(Date:5/5/2015)... 2015 Psyche Systems Corporation and Luminate Health ... first-of-its-kind platform that helps labs comply with new federal ... the way patients engage with these results, and improves ... provides a HIPAA-compliant digital platform that gives labs an ... their lab results, and uniquely connects labs, physicians, and ...
(Date:5/5/2015)... Muncie, IN (PRWEB) May 05, 2015 ... that the state of Indiana, led by Indiana Gov. ... Aviation Day. The AMA Foundation will host a Family ... in celebration. All proceeds will benefit the Wounded Warrior ... by the Academy of Model Aeronautics—the country’s foremost organization ...
(Date:5/5/2015)... LOS ANGELES , May 5, 2015 ... and pioneer in providing on-demand access to scientific, technical ... purchasing agreement with the Association of Southeastern Research ... of 38 research libraries located across 11 southeastern states. ... developing innovative and collaborative programs to address the continually ...
(Date:5/5/2015)...  A group of biotechnology executives and medical doctors ... a non-profit organization dedicated to providing education, research and ... of consciousness.  ... Coma is ... voluntary actions can be initiated by the patient, and ...
Breaking Biology Technology:Psyche Systems Corporation Forms Strategic Alliance with Luminate Health to Provide First-of-its-kind Patient Access Solution 2Psyche Systems Corporation Forms Strategic Alliance with Luminate Health to Provide First-of-its-kind Patient Access Solution 3State of Indiana proclaims August 15 as Model Aviation Day 2Association of Southeastern Research Libraries Partners with Reprints Desk to Improve Access for Hard-to-Find Materials 2Association of Southeastern Research Libraries Partners with Reprints Desk to Improve Access for Hard-to-Find Materials 3Association of Southeastern Research Libraries Partners with Reprints Desk to Improve Access for Hard-to-Find Materials 4Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 2Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 3Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 4Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 5
... 9 Soligenix, Inc. (Soligenix or the Company), (OTC ... that Robert J. Rubin, MD, has been appointed to ... a distinguished career in the healthcare industry and government. ... of the national health policy and management consulting firm ...
... ... Caskey and Saul Tendler to its Scientific Advisory Board , ... Westlake Village, Calif. (PRWEB) October 9, 2009 -- Nanogea, a ... to announce today that Dr. C. Thomas Caskey and Dr. Saul Tendler have joined ...
... ... program and is opening the call for entries. Established in 2003, this prestigious awards ... that manifestly improve some facet of the R&D/drug development/clinical trial process. , ... Needham, MA (PRWEB) October 8, ...
Cached Biology Technology:Soligenix Appoints Robert J. Rubin, MD, to its Board of Directors 2Soligenix Appoints Robert J. Rubin, MD, to its Board of Directors 3Soligenix Appoints Robert J. Rubin, MD, to its Board of Directors 4Nanogea Announces New Scientific Advisory Board Members 2Nanogea Announces New Scientific Advisory Board Members 3The 2010 Bio-IT World Best Practices Call for Entries has been Released -- Highlight your Company's Excellence in Innovation 2The 2010 Bio-IT World Best Practices Call for Entries has been Released -- Highlight your Company's Excellence in Innovation 3
... Kit (E-22013) provides,researchers with a sensitive ... in solution. This fluorescence-based assay can ... (Figure 1). The assay,measures lysozyme activity ... labeled to such a degree that ...
... (Cap Analog) is used for the synthesis ... vitro transcription reactions. Substitution of cap analog ... in an in vitro transcription reaction results ... into a large fraction of the transcripts. ...
The iEMS Incubator/Shaker is a high performance microplate incubator and orbital shaker. Its superior temperature control and efficient orbital shaking reduce incubation times. It can incubate up to ...
iEMS Thermal Microplate Holder...
Biology Products: