Navigation Links
Possible hepatitis C vaccine
Date:9/5/2007

Hepatitis C Virus (HCV) infects up to 500,000 people in the UK alone, many of the infections going undiagnosed. It is the single biggest cause of people requiring a liver transplant in Britain. Now, in a collaborative effort with groups across Europe and the USA, scientists from The University of Nottingham have found monoclonal antibodies which may be a significant step towards a vaccine.

Hepatitis C treatment is expensive and not successful in all patients. Untreated or unresponsive patients can go on to develop cirrhosis of the liver, with life affecting consequences or the need for a liver transplant.

Dr Alexander Tarr, a Research Fellow at the Institute of Infection, Immunity and Inflammation presented a paper Human antibodies to Hepatitis C virus potential for vaccine design at the Society for General Microbiologys 161st meeting which is being held at The University of Edinburgh this week.

The group has recently analysed antibodies that can successfully prevent infection with many diverse strains of Hepatitis C virus in laboratory models. Dr Tarr said: The clinical potential of this work cannot be overstated. Historically, successful vaccines against viruses have required the production of antibodies, and this is likely to be the case for Hepatitis C virus. Identifying regions of the virus that are able to induce broadly reactive neutralising antibodies is a significant milestone in the development of a HCV vaccine, which will have distinct healthcare benefits for hepatitis sufferers, and could also help us design vaccines for other chronic viral diseases such as HIV.

Hepatitis C virus infects 180 million people worldwide. Infection with the virus can lead to liver cancer, and is the most common reason for liver transplantation in both the UK and the USA.

We are also currently exploring the possibility of improving liver transplantation success rates by passively infusing people with these antibodies said Dr Tarr. We are also using the information gained by identifying and characterising the antibody responses to Hepatitis C virus to design new ways of making vaccine candidates. If the antibodies we have discovered can be reproduced by vaccination, control of the disease might be possible.


'/>"/>

Contact: Dr. Alexander Tarr
alex.tarr@nottingham.ac.uk
University of Nottingham
Source:Eurekalert

Related biology news :

1. Viral DNA sequence a possible trigger for breast cancer
2. New studies suggest airborne SARS transmission is possible
3. New method shows it is possible to grow bone for grafts within a patients body
4. Stem Cells Found In Cerebellum; Possible Cell of Origin for Childhood Brain Tumors
5. Possible treatment found for chemobrain
6. Protein amplification in melanoma is possible drug target
7. Is it Possible to Change Prescribing Habits?
8. From one cell, many possible cures
9. Group proves its possible to grow new lung alveoli by growing new blood vessels
10. Oh, rats! Designer animals reveal possible heart disease genes
11. Team discovers possible universal strategy to combat addiction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2017)... Calif. , April 13, 2017 UBM,s ... York will feature emerging and evolving technology ... Both Innovation Summits will run alongside the expo portion ... speaker sessions, panels and demonstrations focused on trending topics ... largest advanced design and manufacturing event will take place ...
(Date:4/11/2017)... 11, 2017 NXT-ID, Inc. (NASDAQ:   ... announces the appointment of independent Directors Mr. Robin D. ... Board of Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , ... forward to their guidance and benefiting from their considerable expertise ...
(Date:4/4/2017)... --  EyeLock LLC , a leader of iris-based identity ... and Trademark Office (USPTO) has issued U.S. Patent No. ... iris image with a face image acquired in sequence ... th issued patent. "The issuance ... multi-modal biometric capabilities that have recently come to market ...
Breaking Biology News(10 mins):
(Date:8/16/2017)... ... August 16, 2017 , ... Recent studies ... type. Many treatments for specific cancers, such as breast, prostate, or lung, target ... androgen deprivation therapy for advanced prostate cancer. , This therapy limits the ...
(Date:8/16/2017)... -- This year,s edition of the Inc. 5000 features a now-familiar name: BioPoint ... made the list for the third year in a row. Now in ... based on a set of quantitative metrics. In addition, BioPoint was also ... the Bay State . ... Inc. 5000 ...
(Date:8/15/2017)... CA (PRWEB) , ... August 15, 2017 , ... ... pioneering graphene biosensors that accelerate pharmaceutical and biotherapeutics development, announces the launch of ... number of steps needed to gain kinetic binding data for a wide range ...
(Date:8/15/2017)... ... 15, 2017 , ... The Conference Forum and The Trout ... a series of upcoming panels and events. The partnership culminates with the 4th ... in New York City. , “With our experience in producing the Immuno-Oncology 360° NYC ...
Breaking Biology Technology: