Navigation Links
Possible hepatitis C vaccine
Date:9/5/2007

Hepatitis C Virus (HCV) infects up to 500,000 people in the UK alone, many of the infections going undiagnosed. It is the single biggest cause of people requiring a liver transplant in Britain. Now, in a collaborative effort with groups across Europe and the USA, scientists from The University of Nottingham have found monoclonal antibodies which may be a significant step towards a vaccine.

Hepatitis C treatment is expensive and not successful in all patients. Untreated or unresponsive patients can go on to develop cirrhosis of the liver, with life affecting consequences or the need for a liver transplant.

Dr Alexander Tarr, a Research Fellow at the Institute of Infection, Immunity and Inflammation presented a paper Human antibodies to Hepatitis C virus potential for vaccine design at the Society for General Microbiologys 161st meeting which is being held at The University of Edinburgh this week.

The group has recently analysed antibodies that can successfully prevent infection with many diverse strains of Hepatitis C virus in laboratory models. Dr Tarr said: The clinical potential of this work cannot be overstated. Historically, successful vaccines against viruses have required the production of antibodies, and this is likely to be the case for Hepatitis C virus. Identifying regions of the virus that are able to induce broadly reactive neutralising antibodies is a significant milestone in the development of a HCV vaccine, which will have distinct healthcare benefits for hepatitis sufferers, and could also help us design vaccines for other chronic viral diseases such as HIV.

Hepatitis C virus infects 180 million people worldwide. Infection with the virus can lead to liver cancer, and is the most common reason for liver transplantation in both the UK and the USA.

We are also currently exploring the possibility of improving liver transplantation success rates by passively infusing people with these antibodies said Dr Tarr. We are also using the information gained by identifying and characterising the antibody responses to Hepatitis C virus to design new ways of making vaccine candidates. If the antibodies we have discovered can be reproduced by vaccination, control of the disease might be possible.


'/>"/>

Contact: Dr. Alexander Tarr
alex.tarr@nottingham.ac.uk
University of Nottingham
Source:Eurekalert

Related biology news :

1. Viral DNA sequence a possible trigger for breast cancer
2. New studies suggest airborne SARS transmission is possible
3. New method shows it is possible to grow bone for grafts within a patients body
4. Stem Cells Found In Cerebellum; Possible Cell of Origin for Childhood Brain Tumors
5. Possible treatment found for chemobrain
6. Protein amplification in melanoma is possible drug target
7. Is it Possible to Change Prescribing Habits?
8. From one cell, many possible cures
9. Group proves its possible to grow new lung alveoli by growing new blood vessels
10. Oh, rats! Designer animals reveal possible heart disease genes
11. Team discovers possible universal strategy to combat addiction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/12/2016)... , May 12, 2016 WearablesResearch.com , ... published the overview results from the Q1 wave of ... recent wave was consumers, receptivity to a program where ... with a health insurance company. "We were ... share," says Michael LaColla , CEO of Troubadour ...
(Date:4/28/2016)... and BANGALORE, India , April 28, ... Systems, a product subsidiary of Infosys (NYSE: INFY ... announced a global partnership that will provide end ... use mobile banking and payment services.      (Logo: ... key innovation area for financial services, but it also plays ...
(Date:4/26/2016)... , April 27, 2016 ... "Global Multi-modal Biometrics Market 2016-2020"  report to their ... , The analysts forecast the global ... of 15.49% during the period 2016-2020.  ... of sectors such as the healthcare, BFSI, transportation, ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016 On ... session at 4,833.32, down 0.22%; the Dow Jones Industrial Average ... 500 closed at 2,085.45, down 0.17%. Stock-Callers.com has initiated coverage ... INFI ), Nektar Therapeutics (NASDAQ: NKTR ), Aralez ... Inc. (NASDAQ: BIND ). Learn more about these ...
(Date:6/23/2016)... India , June 23, 2016 ... media market research report to its pharmaceuticals section ... profiles, product details and much more. ... spread across 151 pages, profiling 15 companies and ... available at http://www.reportsnreports.com/reports/601420-global-cell-culture-media-industry-2016-market-research-report.html . ...
(Date:6/22/2016)... PA (PRWEB) , ... June 22, 2016 , ... ... University City Science Center’s Port business incubator and current participant in the Phase ... and treatment for cancer patients. , Quantitative Radiology Solutions helps physicians make ...
(Date:6/22/2016)... Fla. and ALBANY, N.Y. ... Sciences Corporation (Teewinot) and Albany Molecular Research, Inc. ... AMRI has licensed Teewinot,s technology to produce and ... analytical standard. The CBCA analytical standard is manufactured ... involve the expression of cannabinoid biosynthetic genes in ...
Breaking Biology Technology: