Navigation Links
Pores open the door to death
Date:9/16/2008

This press release is available in German.

Our body is almost constantly being threatened by pathogens and cancerous cells that appear out of the blue. But the body puts up a fight: specialized cells in the immune system smuggle small molecules (granzymes) into cancer cells and those body cells that have fallen prey to viruses. The molecules then trigger off the diseased cells' built-in suicide program. There are two possible ways in which the granzymes gain entry into the cells under attack. Despite more than twenty years of research, however, it remained unclear as to which of these pathways is used to smuggle the lethal amount of granzymes into a cell. Scientists at the Max Planck Institute of Neurobiology have now shown that minute pores on the cell surface open the door to the granzymes for a short period of time. These results provide new prospects for improved methods of treatment of chronic virus infections and cancer. (PNAS, 2. September 2008)

During our day-to-day life, we are rarely aware of the battles taking place in our own bodies. The body is almost always in a state of war against countless pathogens. And so, with every litre of blood that is pumped through our bodies, up to five billion white blood cells are sent out on patrol. Some of these cells react to pathogens by producing antibodies specially designed to attack precisely those pathogens that have been discovered. At the same time, they develop memory cells which recognize these pathogens immediately, should they attack anew.

In addition to these tacticians, a second group of white blood cells takes up arms against the enemy without further hesitation. The group consists of T-cells and killer cells that specialize in singling out body cells that have already been infected by viruses and tumor cells - swift action is therefore essential. However, these attack
'/>"/>

Contact: Dr. Stefanie Merker
merker@neuro.mpg.de
49-898-578-3514
Max-Planck-Gesellschaft
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Bleeding, not inflammation, is major cause of early lung infection death
2. Small-scale fishing in Mexico rivals industrial fisheries in accidental turtle deaths
3. Scientists find how amber becomes death trap for watery creatures
4. Synthetic compound promotes death of lung-cancer cells, tumors
5. Earlier bites by uninfected mosquitoes boost West Nile deaths in lab mice
6. Leading cause of death in preemies might be controlled by resetting a molecular switch
7. The birth and death of dopamine neurons: A new model for neurodegeneration
8. Marsupial lion tops African lion in fight to death
9. Human deaths from shark attacks hit 20-year low last year
10. From delicious to death: Understanding taste
11. Coral reefs and climate change: Microbes could be the key to coral death
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Pores open the door to death
(Date:6/30/2015)... , June 30, 2015 To bolster its efforts ... HYPR Corp. announced today the addition of two new team ... as board advisor and David Raviv will act ... underscore HYPR Corp.,s commitment to providing the most secure solutions ... Sirota co-founded Layer 7 Technologies, a provider of security ...
(Date:6/25/2015)... DALLAS , June 25, 2015 ... report "Fingerprint Sensors Market by Type (Swipe & Area), Technology, ... (Mobile, Government, Healthcare, Commercial Security & Others) & ... published by marketsandmarkets, the said market is expected ... CAGR of 17.1%. Browse 76 ...
(Date:6/24/2015)... 24, 2015 This report provides market analysis ... six years. It contains an analysis of the drivers, ... their impact from the short, medium, and long term ... industry, market, and technology trends that currently, prevail in ... concerned authorities to efficiently manage the increasing marine traffic ...
Breaking Biology News(10 mins):HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4Automatic Identification System Market by Class, by Platform, by Application and by Geography - Global Forecasts & Analysis to 2014 - 2020 2
... -- Children exposed prenatally to tobacco smoke and during childhood ... to research done at Cincinnati Children,s Hospital Medical Center. ... cases in children between the ages of 8 and 15 ... This could translate into up to 800,000 children ...
... November 23, 2009 Agios Pharmaceuticals today announced that ... the mutated IDH1 gene has a novel enzyme activity ... discovery shows that the mutated form of IDH1 produces ... formation and malignant progression of gliomas, the most common ...
... all read studies about the health benefits of having a ... level, where amino acids known as cysteines are much more ... other cysteines. Now, researchers at the University of Michigan, ... system that protects single cysteines. The research appears in the ...
Cached Biology News:Exposure to lead, tobacco smoke raises risk of ADHD 2Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer 2Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer 3Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer 4Saving the single cysteine: New antioxidant system found 2
(Date:7/28/2015)... ... July 28, 2015 , ... ... EUR 1.022 billion in 2013; while production volume reached close to 1.84 million ... country with a share of 75.5% of the region’s total aluminium hydroxide production; ...
(Date:7/28/2015)... July 21, 2015 ... the addition of the "Analysis of the ... their offering. Globally, flow cytometry remains ... cell proliferation, cancer, and stem cells. But the ... primarily because of demand from underdeveloped nations to ...
(Date:7/28/2015)... Research and Markets ( http://www.researchandmarkets.com/research/z54c4k/biomedical ) ... Refrigerators and Freezers Market - Global Industry Analysis, ... 2022" report to their offering. ... has been segmented based on applications: hospitals, research ... The others segment includes applications of biomedical refrigerators ...
(Date:7/28/2015)... ... July 28, 2015 , ... VetStem Biopharma will be offering weekly ... course to local area veterinarians. , The tour and course will be given every ... charge) at VetStem’s Poway facility. Staff members are welcome to attend with their veterinarian ...
Breaking Biology Technology:EU27 Aluminium Hydroxide Market Analysed and Forecast by BAC Reports in New Research Study Available at MarketPublishers.com 2EU27 Aluminium Hydroxide Market Analysed and Forecast by BAC Reports in New Research Study Available at MarketPublishers.com 3Analysis of the Global Flow Cytometry Market 2012-2018 with a 2014 Base Year and a 2015-2018 Forecast Period 2Biomedical Refrigerators and Freezers Market Report - Global Industry Analysis 2015 2Biomedical Refrigerators and Freezers Market Report - Global Industry Analysis 2015 3VetStem Biopharma weekly veterinary continuing education classes and GMP manufacturing facility tour 2
... 2009 convention to be held in ... Georgia, ... international convention on June 17 -- 20, in,San Diego, Calif. Governor Perdue will ... convention., "As one of the fastest-growing industries in the nation, the,biosciences sector ...
... June 4 Oramed Pharmaceuticals,Inc. (OTCBB: ORMP.OB) ... delivery,systems, announced today that it has been ... and Pharmacodynamics (PD) of Oral Insulin in,Healthy ... Diabetes,Association,s Scientific Sessions Conference in San Francisco, ...
... to Allow Company to Make Key Marketing Claims, ... Kangtai,Cactus Biotech Inc. (the "Company") (OTC Bulletin Board: ... of a,variety of cactus-based consumer products in China, ... that received the Company,s Cactus,Cattle Feed. The studies, ...
Cached Biology Technology:Georgia Showcases its Bioscience Leadership at 2008 Bio International Convention 2Georgia Showcases its Bioscience Leadership at 2008 Bio International Convention 3Oramed Pharmaceuticals to Present Oral Insulin Trial Results at ADA Conference (June 6-10, San Francisco) 2Oramed Pharmaceuticals to Present Oral Insulin Trial Results at ADA Conference (June 6-10, San Francisco) 3China Kangtai Cactus Biotech Announces Improved Milk Production in Cows From Company's Cactus Cattle Feed 2China Kangtai Cactus Biotech Announces Improved Milk Production in Cows From Company's Cactus Cattle Feed 3
Attoglow Western Blot Enhancing Kit contains Millennium Enhancer which can significantly boost Western blot signals, and is compatible with other enhancing mechanisms to achieve multiplied enhancing ...
...
Borosilicate Glass. Certified for use with the Beacon 2000 Systems, 1,000 tubes/case...
Although each Beacon 2000 System includes one preinstalled sample chamber (size specified at time of order), optional chambers are available and easily retrofit by the user....
Biology Products: