Navigation Links
Poor growth, delayed puberty and heart problems plague kids with mild kidney disease
Date:8/12/2011

Washington, DC (August 12, 2011) Children with only mildly to moderately impaired kidney function experience poor growth, delays in puberty, and heart problems, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (JASN). Therapies for these conditions might help slow the progression of kidney disease in children.

Heart disease causes almost 35% of deaths in young adults with chronic kidney disease. What factors during childhood might contribute, and how serious do kidney problems have to be before they trigger damage to the heart? To find out, Susan Furth, MD, PhD, of the Children's Hospital of Philadelphia and her colleagues studied 586 children with chronic kidney disease.

Among the major findings:

  • Poor growth, delayed puberty, metabolic problems (such as pH and electrolyte imbalances), and high blood pressure often occurred in children with only mildly or moderately impaired kidneys.
  • Even when children took medications to treat some of these conditions, they were more common as kidney function decreased.

"We were hoping to identify risk factors for CKD progression and see if these can be targeted to slow the decline of kidney function and prevent its complications," said Dr. Furth. "Our findings suggest that more aggressive interventions to improve blood pressure and metabolic abnormalities may be areas where interventions could slow chronic kidney disease progression and decrease the prevalence of cardiovascular disease in children and young adults with chronic kidney disease. The next step will be to design clinical trials of these interventions based on our findings."


'/>"/>

Contact: Adrienne Lea
alea@asn-online.org
American Society of Nephrology
Source:Eurekalert

Page: 1

Related biology news :

1. Interventional radiologists provide hope in delaying growth, spread of breast cancer
2. Joshua E. Neimark Memorial Travel Assistance Award winners investigate stem cell transplantation, sustainable growth, women in academia, and conservation science
3. Fast growth, low defense -- plants facing a dilemma
4. Findings overturn old theory of phytoplankton growth, raise concerns for ocean productivity
5. Black or blue? Mulch color affects okra growth, yield
6. Newly identified growth factor promotes stem cell growth, regeneration
7. Master gene SRC-3 enables breast cancer growth, invasion
8. Plastics chemical retards growth, function of adult reproductive cells
9. Oxygen-free early oceans likely delayed rise of life on planet
10. Muscular dystrophy diagnosis delayed almost 2.5 years in boys
11. GOCE launch delayed until 2009
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... 2016 Perimeter Surveillance & Detection ... Physical Infrastructure, Support & Other Service  The ... offers comprehensive analysis of the global Border Security ... revenues of $17.98 billion in 2016. Now: ... leader in software and hardware technologies for advanced video ...
(Date:5/24/2016)... care by providing unparalleled technology to leaders of the medical imaging industry.  As such, ... to the range of products distributed by Ampronix. Photo - http://photos.prnewswire.com/prnh/20160524/371420 ... ... ... With ...
(Date:5/16/2016)... NEW YORK , May 16, 2016   ... authentication solutions, today announced the opening of an IoT ... to strengthen and expand the development of embedded ... provides an unprecedented level of convenience and security with ... to authenticate one,s identity aside from DNA. EyeLock,s platform ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Md. , June 23, 2016 A person ... from the crime scene to track the criminal down. ... the U.S. Food and Drug Administration (FDA) uses DNA evidence ... Sound far-fetched? It,s not. The FDA ... sequencing to support investigations of foodborne illnesses. Put as simply ...
(Date:6/23/2016)... --  EpiBiome , a precision microbiome engineering company, today ... from Silicon Valley Bank (SVB). The financing will allow ... drug development efforts, as well as purchase additional lab ... been an incredible strategic partner to us – one ... provide," said Dr. Aeron Tynes Hammack , EpiBiome,s ...
(Date:6/23/2016)... 2016  Blueprint Bio, a company dedicated to identifying, ... community, has closed its Series A funding round, according ... "We have received a commitment from Forentis Fund ... to meet our current goals," stated Matthew Nunez ... to complete validation on the current projects in our ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... of intelligent tools designed, tuned and optimized exclusively for Okuma CNC machining centers ... The result of a collaboration among several companies with expertise in toolholding, cutting ...
Breaking Biology Technology: