Navigation Links
Pollen cells keep memory to control jumping genes
Date:9/20/2012

) and Filipe Borges (in the Becker lab) observed that DNA methylation is largely maintained in the microspores and pollen grains. But there are differences between the different cell types. In the pollen grain, some DNA sequences are methylated in sperm cells but not in the vegetative nucleus, and vice versa. Amongst these non-methylated genes are mobile sequences of DNA, called transposable elements, which could become active and lead to mutagenic effects.

The research team discovered that the situation is rescued by small sequences of RNA (called siRNAs) that restore methylation of transposable elements in the embryo. Indeed, they have found siRNA in sperm cells that silence the transposable elements even before fertilisation, in at least some cases. Transposable elements are very common in all known genomes. In the human genome, for example, they make up 45% of the total genome. They are involved in the evolution of genomes, since when integrated back into the genome they can affect the function and organisation of other genes. However, transposable elements are mutagens, and, therefore, their activation needs to be under tight control, as it may be harmful to the cell and the organism. If such harmful mutations occur in sexual cells, they will be transmitted to the progeny and spread in the population.

Says Jrg Becker, 'We have unveiled a mechanism in the sexual cells that can prevent the activation of potentially harmful transposable elements, while at the same time, upon fusion of sperm cell and egg cell, allowing the formation of a cell with full capacity to become any cell type, that will give rise to a new generation. On the other hand, if female siRNAs in the egg cell do not match incoming transposable elements from the male, they might escape silencing in the developing embryo, with potentially harmful implications for the new plant that is generated. Such an uncontrolled activation of transposable elements might at least in part explain existin
'/>"/>

Contact: Ana Mena
anamena@igc.gulbenkian.pt
351-214-407-959
Instituto Gulbenkian de Ciencia
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Pollen can protect mahogany from extinction
2. Precision motion tracking -- thousands of cells at a time
3. Study in mice discovers injection of heat-generating cells reduces belly fat
4. UCLA researchers discover missing link between stem cells and immune system
5. Keep your distance! Why cells and organelles dont get stuck
6. A new look at proteins in living cells
7. Astrocytes control the generation of new neurons from neural stem cells
8. CYCLOPS genes may serve as an Achilles heel in tumor cells
9. Stem cells may prevent post-injury arthritis
10. Anti-aging elixir for solar cells
11. Embryonic blood vessels that make blood stem cells can also make beating heart muscles
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Pollen cells keep memory to control jumping genes
(Date:9/23/2014)... tissues during the healing process, cells must be ... scientists believed this communication happened primarily through chemical ... the University of Pittsburgh have found that another ... not more crucial. The findings, published in this ... National Academy of Sciences , could lead to ...
(Date:9/23/2014)... cow rumens and termite guts for microbes that can ... of next-generation biofuels, but some of the best microbial ... researchers report. , Their study , reported in ... , is the first to use biochemical approaches to ... can digest fiber, breaking it down into simple sugars ...
(Date:9/23/2014)... vegetable consumption could be as good for your mental ... research, conducted by the University of Warwick,s Medical School ... published by BMJ Open focused on mental ... were consistently associated with an individual,s fruit and vegetable ... ate five or more portions of fruit and vegetables ...
Breaking Biology News(10 mins):The mechanics of tissue growth 2Search for better biofuels microbes leads to the human gut 2Search for better biofuels microbes leads to the human gut 3Eating five a day may keep the blues away 2
... 11, 2012) The naked mole rat, a curiously strange, ... or rat. Scientists at The University of Texas Health Science ... continue to explore this mystery. On May 2 a ... machines for protein disposal called proteasome assemblies differ ...
... ON Lawson Health Research Institute announced today that it ... the Bill & Melinda Gates Foundation. Dr. Gregor Reid ... receive funding from the Gates Foundation. The research ... the nutrient rich plant called Moringa on the health outcomes ...
... A brain study in infant rats demonstrates that the ... new questions about using the first-line drug to treat ... Neurology EarlyView posted online May 11, researchers at ... drug phenobarbital given to rat pups about a week ...
Cached Biology News:Scientists find differences in naked mole rat's protein disposers 2Lawson recieves Grand Challenges Explorations grant for groundbreaking research 2Study raises questions about use of anti-epilepsy drugs in newborns 2Study raises questions about use of anti-epilepsy drugs in newborns 3
(Date:9/23/2014)... September 23, 2014 Erlab , ... personnel since 1968 and Burdinola, supplier of laboratory furniture ... new filtered fume hood. , By integrating ... hood, Burdinola will now offer an innovative solution utilizing ... range of chemicals, best-in-class detection technology, and communication for ...
(Date:9/23/2014)... 2014 ATCC, the premier global biological ... two important appointments to the senior leadership team. Barbie ... Strategy and Technology and Dr. Maryellen de Mars also ... Center. Both roles are new positions at ATCC. ... CEO at ATCC described the additions as part of ...
(Date:9/23/2014)... 23, 2014 Follow us ... steady popularity the world over, due to its ... in the marketplace is expected to come from ... developing countries. Several sub-Saharan countries in the African ... already implemented genetically engineered crop production strategies. Rising ...
(Date:9/23/2014)... 2014 News Facts , ... devoted to genome-based research for human health and disease, ... taking a bite out of oral cancer with its world-class ... India with the help of state-of-the-art solution ... (DDN). , To fuel its cutting-edge cancer research, the ...
Breaking Biology Technology:Erlab Partners with Burdinola to Deliver an Innovative Filtered Fume Hood 2ATCC Announces New Appointments to its Leadership Team 2ATCC Announces New Appointments to its Leadership Team 3Rising Focus on Food Security Spurs Growth in the Global Agricultural Biotechnology Market, According to New Report by Global Industry Analysts, Inc. 2Rising Focus on Food Security Spurs Growth in the Global Agricultural Biotechnology Market, According to New Report by Global Industry Analysts, Inc. 3Rising Focus on Food Security Spurs Growth in the Global Agricultural Biotechnology Market, According to New Report by Global Industry Analysts, Inc. 4National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 2National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 3National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 4National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 5
... made tremendous scientific advances by dissecting apart the ... at the University of Wisconsin-Madison College of Engineering ... the pieces back together, mathematically. , John Yin, ... computer models of a relatively simple virus to ...
... SCOTTSDALE, Ariz., Feb. 6 Cancer Clinics of ... community oncologists, announced the completion of its 62nd ... leading oncology disease states at the 4th Annual ... oncology group is now fully prepared to launch ...
... LLC, a clinical-stage drug development company commercializing first-in-class ... completion of a $2.9 million private placement. ... and clinical programs for its lead drug compound, ... David G. Kalergis, Chief Executive Officer of Diffusion ...
Cached Biology Technology:Mathematical models reveal how organisms transcend the sum of their genes 2Cancer Clinics of Excellence (CCE) Releases 62nd Evidence-Based Treatment Protocol 2Diffusion Pharmaceuticals Announces Completion of a $2.9 Million Private Placement and Company Presentations at Upcoming Industry Conferences in Geneva, Switzerland and Naples, Florida 2Diffusion Pharmaceuticals Announces Completion of a $2.9 Million Private Placement and Company Presentations at Upcoming Industry Conferences in Geneva, Switzerland and Naples, Florida 3
Mouse monoclonal [4i144] to HLA Class II DQ1 7 ( Abpromise for all tested applications). Antigen: Full length protein (Human): HLA Class 2 Antigen DQ1,7....
ASCIZ...
Goat polyclonal to CHMP5 ( Abpromise for all tested applications). Antigen: Synthetic peptide: C-NKDGVLVDEFGLPQ, corresponding to C terminal amino acids 202-215 of Human CHMP5 Entrez GeneID: ...
...
Biology Products: