Navigation Links
Playing it safe
Date:7/7/2009

This release is available in German.

Kinarm Ko and Hans Schler's team at the Max Planck Institute for Molecular Biomedicine in Mnster have succeeded for the first time in culturing a clearly defined cell type from the testis of adult mice and converting these cells into pluripotent stem cells without introduced genes, viruses or reprogramming proteins. These stem cells have the capacity to generate all types of body tissue. The culture conditions alone were the crucial factor behind the success of the reprogramming process. (Cell Stem Cell, July 2, 2009)

The testis is a sensitive organ and an astonishing one at that. Even at the age of 70, 80 or 85, men have cells that constantly produce new sperm. Therefore, they can conceive embryos and become fathers at almost any age - assuming they can find a sufficiently young female partner. Based on this, researchers have long assumed that cells from the testis have a similar potential as in embryonic stem cells: that is, a pluripotency that enables them to form over 200 of the body's cell types.

In fact, a number of researchers have recently stumbled on the multiple talents in the male gonads of humans and mice. It all began with the work of Takashi Shinohara's team in 2004. The Japanese scientists discovered that, like embryonic stem cells, certain cells in the testis of newborn mice are able to develop into different kinds of tissue. In 2006, scientists working with Gerd Hasenfu and Wolfgang Engel in Gttigen reported that such adaptable cells can also be found in adult male mice. Additionally, Thomas Skutella and his colleagues at the University of Tbingen recently made headlines when they cultured comparable cells from human testis tissue.

A bewildering variety of cells

"At first glance, it would appear that it has long been established that pluripotent cells
'/>"/>

Contact: Dr. Jeanine Mller-Keuker
presse@mpi-muenster.mpg.de
49-251-703-65325
Max-Planck-Gesellschaft
Source:Eurekalert  

1

GOOD

Page: 1 2 3

Related biology news :

1. Golf course: Playing fields, wildlife sanctuaries or both
2. Playing dead is no game for ant survival
3. Arctic climate models playing key role in polar bear decision
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Playing it safe
(Date:5/23/2013)... HOUSTON (May 23, 2013) A new report ... responsible for helping pupils engage in at least 60 ... school day. , No more than half of American ... hour of vigorous or moderate intensity physical activity daily, ... , "Because children are in school for nearly half ...
(Date:5/23/2013)... Inside the natural history museums of the world are ... and beetles to flowers, mushrooms and grasses, all stacked, ... The rich and diverse collections could be critical to ... face of a growing human footprint if only ... project, brought to life with the help of a ...
(Date:5/23/2013)... the team reveal the interplay of brain chemicals which ... Wellcome Trust and BBSRC. , By changing the ... perceptual abilities. While these changes can affect the strength ... fidelity of that response. , Lead author ... communicate with others, you can make yourself better heard ...
Breaking Biology News(10 mins):Schools should provide students with daily physical activity, IOM recommends 2CU-Boulder helps tap crowds to digitize museum records of bugs and plants 2CU-Boulder helps tap crowds to digitize museum records of bugs and plants 3CU-Boulder helps tap crowds to digitize museum records of bugs and plants 4
... understanding of spinocerebellar ataxiaResearchers have discovered how the abnormal ... that lead to the death of neurons that govern ... theory that neurodegenerative disorders can be caused by having ... mutated one. , People who are afflicted with the ...
... uses different pathways to invade red blood cells, ... create effective vaccines against the disease. A research team ... scholar with the Howard Hughes Medical Institute, has identified ... and forth between invasion pathways. , Researchers from ...
... Cornell University researchers have revealed a process that has ... derived from vitamin A enters a cell's nucleus, where ... basic transport mechanism opens a new door for future ... for the fight against cancer and other diseases. , ...
Cached Biology News:Pinpointing the cause of a neurodegenerative disorder 2Pinpointing the cause of a neurodegenerative disorder 3Gene expands malaria's invasion options 2Gene expands malaria's invasion options 3Study shows how retinoic acid enters a cell's nucleus 2Study shows how retinoic acid enters a cell's nucleus 3
(Date:5/23/2013)... -- BioScrip, Inc. (NASDAQ: BIOS ) today announced ... Global Healthcare Conference to be held June 3-6, 2013 ... Richard Smith , President and Chief Executive ... Financial Officer, will present on Monday, June 3, 2013 ... About BioScrip BioScrip, Inc. provides comprehensive infusion and ...
(Date:5/23/2013)... 23, 2013  Rahal Letterman Lanigan Racing (RLL) and ... stem cell banking and therapeutics, announced today that StemCyte ... Acorn Stairlifts Indy car driven by James ... the IZOD IndyCar 2013 season.   StemCyte, ... support awareness of umbilical cord blood banking and its ...
(Date:5/23/2013)... MENLO PARK, Calif. , May 23, 2013 /PRNewswire/ ... an oral treatment for pain has reached an important ... clinical trial of VBY-036 - a selective cathepsin S ... of VBY-036 is a double-blind, randomized, placebo-controlled study designed ... escalating doses of VBY-036 in healthy adults. ...
(Date:5/23/2013)... May 23, 2013 The New Jersey ... industries, Black Data Processing Associates (BDPA), is hosting its ... 8, 2013. This all-day event will encourage students and ... the ins and outs from many of the industries’ ... at the New Jersey Institute of Technology, the event ...
Breaking Biology Technology:StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3Virobay, Inc. initiates a Phase 1 Trial of VBY-036, a compound intended for the treatment of neuropathic pain 2Virobay, Inc. initiates a Phase 1 Trial of VBY-036, a compound intended for the treatment of neuropathic pain 3Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 2
... After two days of demostrating Wisconsin's breakthroughs in ... closed last Wednesday with a discussion of what the state ... investors praised the strides Wisconsin has made in research, but ... , ,Tom Still, moderator of the panel and president ...
... exec pal of mine has observed that many IT shops ... is, of course, an acronym. While I have been known to scramble ... clever. MUD stands for machine under desk. , ,The problem ... little computing shop right at their desk without the first concern for ...
... Pictured: Dan Vogel, Department of Health and Human Services; ... of Health and Human Services and park warden at ... Arusha, Tanzania Even if former ... the Bush administration, his legacy at the Department of ...
Cached Biology Technology:Out-of-state VCs offer advice on biotech investments 2Out-of-state VCs offer advice on biotech investments 3Is your IT stuck in the MUD? 2Is your IT stuck in the MUD? 3Thompson's HHS legacy will include efforts to combat disease in Africa 2Thompson's HHS legacy will include efforts to combat disease in Africa 3
... Benzonase is a trademark of Merck KGaA. Physical ... HCl, pH 8.0, 2 mM MgCl 2 , and ... digest sonicated herring sperm DNA to acid-soluble oligonucleotides equivalent ... min at pH 8.0 at 37 C (reaction volume ...
... StabilCoat Immunoassay Stabilizer is an aqueous ... and other non-toxic chemicals in a PBS ... 7.4. This product does not contain ... the conformation and activity of dried protein ...
... is a bovine protein-free alternative to ... an aqueous solution that contains non-toxic ... (3-(N-Morpholino) propanesulfonic acid), pH 6.0 - ... 0.02% methylisothiazolone and 0.02% bromonitrodioxane as ...
Mouse monoclonal antibody to PARK2 - Parkinson disease (autosomal recessive, juvenile) 2, parkin...
Biology Products: