Navigation Links
Plavix may be treatment for dogs at risk of thromboembolic disease
Date:7/14/2010

Athens, Ga. Companion animals that have a long-term need for anticoagulant drug therapies may soon find help in a top-selling antiplatelet drug marketed to humans: clopidogrel, commonly known by the trade-name Plavix.

Researchers in the University of Georgia College of Veterinary Medicine have found that clopidogrel may be a safe and effective treatment for dogs that need long-term anticoagulant therapy. In addition, it may offer a safe alternative to NSAIDs for treating dogs at risk of thromboembolism due to concurrent therapeutic use of corticosteroids.

Other than aspirin, there are currently no approved antiplatelet drug therapies available to prophylactically treat companion animals with known or suspected hypercoagulability. Anticoagulants such as heparin, which must be administered by injection, are often used instead, but for patients who need long-term treatment, the researchers on the study said many animal owners are reluctant to administer injectable drugs to their pets.

In addition, critically ill dogs are at risk for thromboembolic disease, including pulmonary and aortic thromboembolism, both of which are associated with severe illness and death. Dogs that develop thrombosis and are subsequently treated with thrombolytic agents are at a substantial risk of hemorrhage or metabolic instability.

The researchers wanted to evaluate clopidogrel as a potential treatment for dogs with hypercoagulability due to excessive platelet activation. Clopidogrel, which is only available as an oral therapy, has been safely administered to cats, rabbits and calves, but little has been published about its effects in dogs.

In a study of healthy dogs, researchers found that most dogs had a significant inhibition of platelet function within three hours of receiving clopidogrel. All of the dogs in the study tolerated the drug well and showed no evidence of bruising, hemorrhage or other adverse effects. In addition, pl
'/>"/>

Contact: Kat Gilmore
kygilmore@uga.edu
706-583-5485
University of Georgia
Source:Eurekalert

Page: 1 2

Related biology news :

1. Breast cancer treatment resistance linked to signaling pathway
2. The dietary supplement genistein can undermine breast cancer treatment
3. Coming soon: Self-guided, computer-based depression treatment
4. Nanodiamond drug device could transform cancer treatment
5. Disinfectants can make bacteria resistant to treatment
6. Scientists from Granada find a potential treatment to prevent diabetes and obesity
7. FSU researchers discovery leads to $1.5 million grant, potential new treatment of liver fibrosis
8. Researchers at National Jewish Health evaluating a treatment
9. National Jewish Health researchers evaluating treatment to help emphysema sufferers breathe easier
10. First comprehensive genomic study of common cold reveals new treatment targets
11. Iowa State researcher develops new treatment method for canine eye diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2015)... 14, 2015  HYPR Corp. today announced it ... ) Alliance tm , an industry consortium transforming ... to share technology and collaborate to deliver open ... more secure and private, and easier to use. ... that protects sensitive user information and eliminates the ...
(Date:4/13/2015)... According to a recently ... & Opportunities, 2020", the global biometrics market is ... till 2020. The biometrics market is garnering attention ... review of biometric management systems. The constant development ... greater efficiency, are resulting in increasing installation of ...
(Date:4/10/2015)... Research and Markets ( http://www.researchandmarkets.com/research/cjk4gb/security ... Competitive Profiles - NEC" report to their offering. ... will continue to supply a range of IT security ... company focus on the development of a Big Data ... in the Asia-Pacific region is ...
Breaking Biology News(10 mins):HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NEC Security Competitive Profile 2015 2
... collaborators have found, in a previously identified gene, a ... of isolated cleft lip. It is the first time ... alone, rather than both cleft lip and palate. ... mechanism and could eventually help with diagnosis, prevention and ...
... et al.report in the Journal of Cell Biology ... metastatic movement in tumor cells., On 2D surfaces, cells ... link the cell to the extracellular matrix, are known ... has been unclear. Recent work has suggested that an ...
... material could speed development of hydrogen powered vehicles , ... a new material that almost meets the U.S. Department of ... eliminate a key roadblock to practical hydrogen-powered vehicles. Their study ... is scheduled for the Oct. 8 issue of ACS, ...
Cached Biology News:Study finds genetic variant plays role in cleft lip 2Study finds genetic variant plays role in cleft lip 3American Chemical Society's Weekly PressPac 2American Chemical Society's Weekly PressPac 3American Chemical Society's Weekly PressPac 4American Chemical Society's Weekly PressPac 5American Chemical Society's Weekly PressPac 6American Chemical Society's Weekly PressPac 7American Chemical Society's Weekly PressPac 8
(Date:4/23/2015)... 2015 Six startups from Russia ... 4-17 as part of the U.S.-Russia Innovation Corridor ... of biotechnology startups to participate in the program ... and the University of Maryland (UMD) signed a ... respective universities in the biomedical industry in 2013. ...
(Date:4/23/2015)... , April 23, 2015 WuXi PharmaTech (Cayman) ... capability and technology platform company serving the pharmaceutical, biotechnology ... China and the United States ... results for the first quarter of 2015 after the ... 2015 (which will be Thursday morning, May 14, 2015 ...
(Date:4/23/2015)... 2015  Cryoport, Inc. (OTCBB: CYRX) ("Company"), the ... the life sciences industry, today announced that the ... within the animal husbandry market by signing a ... the shipment of equine semen for artificial insemination ... Animal husbandry is a multi-billion dollar ...
(Date:4/23/2015)... -- Prospects for Leading Companies in OTC, ...   We predict the global healthcare packaging ... 2015 and will grow at a CAGR of 6.3% between ... the world and increasing functional requirements for healthcare packaging products ... healthcare packaging market. A global ageing population, changing ...
Breaking Biology Technology:U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 2U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 3U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 4WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 2WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 3Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 2Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 3Healthcare Packaging Market Forecast 2015-2025 2Healthcare Packaging Market Forecast 2015-2025 3Healthcare Packaging Market Forecast 2015-2025 4Healthcare Packaging Market Forecast 2015-2025 5Healthcare Packaging Market Forecast 2015-2025 6Healthcare Packaging Market Forecast 2015-2025 7Healthcare Packaging Market Forecast 2015-2025 8Healthcare Packaging Market Forecast 2015-2025 9Healthcare Packaging Market Forecast 2015-2025 10
... May 2011 - Optical data carriers such as DVDs, ... "phase change materials". In the future, these materials will ... memories. A prerequisite for this is a low thermal ... conductivity even in the crystalline state. This is described ...
... BELGRADE, Mont., May 3, 2011 Bacterin International Holdings, ... developer of revolutionary bone graft material, today announced that, ... in a private placement transaction.  The transaction was funded ... the date each tranche was submitted to NYSE Amex ...
... Reportlinker.com announces that a new market research report is ... Technologies and Global Markets http://www.reportlinker.com/p0488650/Medical-Enzymes-Technologies-and-Global-Markets.html ... medicine is growing. The global market for medical enzymes ... is growing at a compound annual growth rate (CAGR) ...
Cached Biology Technology:Nature of bonding determines thermal conductivity 2Nature of bonding determines thermal conductivity 3Bacterin International Secures $1.9 million in Private Placement 2Bacterin International Secures $1.9 million in Private Placement 3Reportlinker Adds Medical Enzymes: Technologies and Global Markets 2Reportlinker Adds Medical Enzymes: Technologies and Global Markets 3Reportlinker Adds Medical Enzymes: Technologies and Global Markets 4Reportlinker Adds Medical Enzymes: Technologies and Global Markets 5Reportlinker Adds Medical Enzymes: Technologies and Global Markets 6Reportlinker Adds Medical Enzymes: Technologies and Global Markets 7Reportlinker Adds Medical Enzymes: Technologies and Global Markets 8Reportlinker Adds Medical Enzymes: Technologies and Global Markets 9Reportlinker Adds Medical Enzymes: Technologies and Global Markets 10Reportlinker Adds Medical Enzymes: Technologies and Global Markets 11Reportlinker Adds Medical Enzymes: Technologies and Global Markets 12Reportlinker Adds Medical Enzymes: Technologies and Global Markets 13
Human TSLP MAb (Clone 258136)...
HiTrap NHS-activated HP, 1 x 5 ml. Category: Chromatography Systems & Accessories, Systems....
Human OSCAR MAb (Clone 259501)...
Human/Mouse G9a/EHMT2 MAb (Clone A8620A) Keywords: Eu-HMTase2...
Biology Products: