Navigation Links
Plastics chemical retards growth, function of adult reproductive cells
Date:7/8/2009

CHAMPAIGN, Ill. Bisphenol A, a chemical widely used in plastics and known to cause reproductive problems in the offspring of pregnant mice exposed to it, also has been found to retard the growth of follicles of adult mice and hinder their production of steroid hormones, researchers report.

Their study is the first to show that chronic exposure to low doses of BPA can impair the growth and function of adult reproductive cells. The researchers will describe their findings this month at the annual meeting of the Society for the Study of Reproduction.

A healthy, mature follicle, called an antral follicle, includes a single egg cell surrounded by layers of cells and fluid which support the egg and produce steroid hormones, said University of Illinois veterinary biosciences professor Jodi Flaws, who led the study with graduate student Jackye Peretz.

"These are the only follicles that are capable of ovulating and so if they don't grow properly they're not going to ovulate and there could be fertility issues," Flaws said. "These follicles also make sex steroid hormones, and so if they don't grow properly you're not going to get proper amounts of these hormones." Such hormones are essential for reproduction, she said, "but they're also required for healthy bones, a healthy heart and a healthy mood."

BPA is widely used in plastics and is a common component of food containers and baby bottles.

The chemical structure of BPA is similar to that of estradiol, a key steroid hormone, and it can bind to estrogen receptors on the surface of some cells. It is not known whether BPA blocks, or mimics or enhances estrogen's activity on these cells, Flaws said.

Human studies have found BPA in many tissues and fluids, including urine, blood, breast milk, the amniotic fluid of pregnant women and the antral fluid of mature follicles. A national survey conducted by the federal Centers for Disease Control and Prevention in 2003-2004 fou
'/>"/>

Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

0

GOOD

Page: 1 2 3

Related biology news :

1. Green plastics could help reduce carbon footprint
2. Kalyon wins Society of Plastics Engineers 2008 Research Award
3. Plastics suspect in lobster illness
4. Protein fibrils as alternative plastics?
5. Boost for green plastics from plants
6. Simplifying manufacture of drugs, plastics earns UH chemist top honor
7. New way to make sensors that detect toxic chemicals
8. Scientists track chemical changes in cells as they endure extreme conditions
9. Chemicals in common consumer products may play a role in pre-term births
10. Kelvin Lee winner of Biochemical Engineering Journal Young Investigator Award
11. American Chemical Societys Weekly Presspac -- June 17, 2009
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Plastics chemical retards growth, function of adult reproductive cells
(Date:5/21/2013)... of Michigan Water Center today awarded 12 research ... restoration and protection efforts. , The two-year grants ... including efforts to track the remediation of harmful ... control non-native weedy plant invasions; study chromosomal damage ... to restoration activities. , The grants were awarded ...
(Date:5/21/2013)... decades, scientists have developed many devices that can reopen ... generally effective, each of these treatments has drawbacks, including ... from MIT analyzes the potential usefulness of a new ... drug-releasing stents, but may pose fewer risks. With this ... for only a brief period, during which it releases ...
(Date:5/20/2013)... also commonly resistant to antimicrobial substances made by ... mBio , the online open-access journal of ... and host antimicrobials LL-37 and lysozyme, which help ... that patients with life-threatening multi-drug resistant infections are ... is a last-line drug for treating several kinds ...
Breaking Biology News(10 mins):U-M Water Center awards $570K in Great Lakes restoration grants 2U-M Water Center awards $570K in Great Lakes restoration grants 3U-M Water Center awards $570K in Great Lakes restoration grants 4Evaluating a new way to open clogged arteries 2Evaluating a new way to open clogged arteries 3Resistance to last-line antibiotic makes bacteria resistant to immune system 2Resistance to last-line antibiotic makes bacteria resistant to immune system 3
... It,s commonly known, at least among microbiologists, that ... dormancy. Dormant microbes are less like zombies ... is how large numbers of dormant microorganisms affect the ... In the current issue of Nature Reviews: Microbiology ...
... common connective tissue cell in animals is the fibroblast, which ... Neta Erez of Tel Aviv University,s Sackler Faculty of Medicine ... great harm, helping to "recruit" immune cells for tumor growth. ... cancer cell proliferation is beginning, fibroblasts rush to the scene ...
... have developed a novel system for delivery of growth ... diabetic foot ulcers. In their work published in ... of Sciences , the team from the MGH Center ... keratinocyte growth factor (KGF), a protein known to play ...
Cached Biology News:The undead may influence biodiversity, greenhouse gas emissions 2Infiltrating cancer's recruitment center 2Growth-factor-containing nanoparticles accelerate healing of chronic wounds 2
(Date:5/22/2013)... NEW ORLEANS , May 22, 2013 ... of regenerative medicine, presented new data generated in collaboration ... (a leading health economics consultancy) demonstrating the significant healthcare ... and venous leg ulcers (VLU) place upon the US ... research, which reveal annual costs of up to $15 ...
(Date:5/22/2013)... 2013 Express Diagnostics Int’l, Inc. ... are pleased to announce a sponsorship agreement with ... New Zealand distributor of DrugCheck® onsite testing devices, manufactured ... in the Austin 400 May 17-19 in Austin, Texas. ... that involves each car of the Erebus Motorsport team ...
(Date:5/22/2013)... 22, 2013  Moderna Therapeutics, the pioneering company developing ... enable the in vivo production of therapeutic ... will join Moderna in early July as its ... a proven leader in the design and implementation of ... discovery to translation, clinical operations and commercial preparedness. John ...
(Date:5/21/2013)... Through science fairs, workshops, kits for ... equipment, 25 organizations will continue their work to increase ... photonics in daily life with the aid of ... in 10 countries, are the first of two groups ... SPIE, the international society for optics and photonics , ...
Breaking Biology Technology:Organogenesis Presents Findings from Groundbreaking Research Highlighting the Healthcare Resource and Economic Burden of Venous Leg Ulcers and Diabetic Foot Ulcers 2Organogenesis Presents Findings from Groundbreaking Research Highlighting the Healthcare Resource and Economic Burden of Venous Leg Ulcers and Diabetic Foot Ulcers 3Organogenesis Presents Findings from Groundbreaking Research Highlighting the Healthcare Resource and Economic Burden of Venous Leg Ulcers and Diabetic Foot Ulcers 4Australian Distributor of Express Diagnostics Signs Sponsorship Agreement with V8 Supercar Team 2Industry Leader John Reynders Joins Moderna Therapeutics as Chief Information Officer 2Industry Leader John Reynders Joins Moderna Therapeutics as Chief Information Officer 3Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 2Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 3
... ChanTest, the leading expert in ion channels and ... development, and safety -- is one of eight organizations ... and Commercialization Program. Governor Ted Strickland and Interim Director ... the Ohio Third Frontier Commission, Mark Barbash, announced the ...
... Aegera Therapeutics is pleased to announce the initiation ... AEG33773, a novel, orally bio-available small molecule therapeutic ... , The Phase 2a study, entitled A Multicenter, ... Efficacy of AEG33773 versus Placebo in Patients with ...
... May 6 iZumi Bio, Inc., a biotechnology ... stem cell (iPS) technology with the mission of ... differentiation of patient cells, today announced the appointments ... (CTO) and Dushyant Pathak, Ph.D., as vice president ...
Cached Biology Technology:ChanTest Awarded $4.8 Million Through the Ohio Third Frontier Research and Commercialization Program 2ChanTest Awarded $4.8 Million Through the Ohio Third Frontier Research and Commercialization Program 3Aegera Initiates Phase 2 Clinical Trial Of AEG33773 - A Small Molecule Targeting Neuropathic Pain 2iZumi Bio Appoints Dr. Berta Strulovici as Chief Technology Officer and Dr. Dushyant Pathak as Vice President of Business Development 2iZumi Bio Appoints Dr. Berta Strulovici as Chief Technology Officer and Dr. Dushyant Pathak as Vice President of Business Development 3
2,4-Dinitrophenyl hapten is conjugated to Human Serum Albumin (HSA) protein through lysine....
PGF1α-d4 contains 4 deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGF1α by GC- or LC-mass spectrometry....
PGD2-d4 contains 4 deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry....
Request Info...
Biology Products: