Navigation Links
Plasma DNA level is a reliable marker of recurrent esophageal cancer, study finds
Date:7/25/2008

CHICAGO (July 25, 2008) New research published in the July issue of the Journal of the American College of Surgeons shows elevated plasma DNA is a reliable marker of recurrent esophageal cancer. The study also suggests that plasma DNA levels rise before clinical evidence of cancer recurrence in the majority of patients.

Esophageal cancer, one of the leading causes of cancer death worldwide, is usually diagnosed at a late stage. An accurate marker for detecting esophageal cancer that has spread (metastasized) beyond the esophagus may allow for better selection of patients for adjuvant therapy, prediction of response to therapy and early intervention when the disease does recur. Although carcinoembryonic antigen (CEA) and plasma DNA are known to be elevated in patients with esophageal cancer and are higher in patients with metastatic disease, the sensitivity and specificity of these markers in the diagnosis of recurrent cancer has not been compared.

"The diagnosis of metastatic esophageal cancer prior to surgery and recurrent disease after surgery remains challenging, as the clinical staging of esophageal cancer is difficult and current scanning technologies are limited," said Farzaneh Banki, MD, assistant professor of surgery, Department of Surgery, Keck School of Medicine at the University of California, Los Angeles. "The results of our study suggest that measuring DNA levels could improve the diagnosis of and prediction of recurrence of this disease."

The study analyzed the sensitivity and specificity of plasma DNA as a preoperative marker of metastasized disease and a postoperative marker in residual or recurrent esophageal cancer. Plasma DNA was measured in 45 patients with esophageal cancer and 44 healthy volunteers; serum CEA was measured in 31 patients.

Plasma DNA was found to be more sensitive than CEA for detecting cancer that cannot be removed through a surgical procedure (100 percent versus 40 percent)
'/>"/>

Contact: Sally Garneski
pressinquiry@facs.org
312-202-5409
Weber Shandwick Worldwide
Source:Eurekalert

Page: 1 2

Related biology news :

1. Low levels of key protein may indicate pancreatic cancer risk
2. Gray whales a fraction of historic levels, genetic research says
3. Folic acid lowers blood arsenic levels, according to Mailman School of Public Health study
4. Study finds that even aloof husbands have lower testosterone levels than unmarried men
5. Folic acid lowers blood arsenic levels in Bangladesh
6. Natural product discovery by Cleveland medical researchers blocks tissue destruction
7. Wildfire drives carbon levels in northern forests
8. University of Toronto finds humans and chimps differ at level of gene splicing
9. Even minute levels of lead cause brain damage in children
10. Cleveland Clinic leading clinical program to improve early-stage lung cancer detection
11. Manure management reduces levels of antibiotics and antibiotic resistance genes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... Dec. 15, 2014 Research and Markets ... of the "Samsung Galaxy S5 - Home ... to their offering. ... different sensing technology than the iPhone 5S, Samsung ... in its product. The Galaxy S5 ...
(Date:12/17/2014)... -- Valencell, a leader in performance biometric data sensor ... leaders such as Intel, Jabra, Atlas, and Scosche to ... These products will be showcased at CES 2015, taking ... . "Our partners choose PerformTek biometrics, ... with the clinical data to back it up," said ...
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... addition of the "Global Facial Recognition Market ... http://photos.prnewswire.com/prnh/20130307/600769 Facial ... of individuals. Facial recognition system measures the overall ... jaw edges, mouth, and the distance between eyes. ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3
... according to results of a new technique reported in ... National Academy of Sciences by researchers from Lawrence Livermore ... The researchers created a molecular clock by looking ... virus collected in 47 locations around the world, from ...
... Fund scientists said today that the discovery of 11 new ... Vietnam underscores the importance of conservation efforts in the ancient ... the ancient tropical forests of a region known as Vietnams ... butterflies as well as three other plants new to science ...
... ARBOR, Mich.---Unhealthy options and pressures influence nearly every part ... week in a special supplement of the American Journal ... work conducted at the University of Michigan, reveal that, ... contracts with soft drink bottling companies give students easy ...
Cached Biology News:New molecular clock from LLNL and CDC indicates smallpox evolved earlier than believed 2New molecular clock from LLNL and CDC indicates smallpox evolved earlier than believed 3New animal and plant species found in Vietnam 2Studies: Children obese due to a host of unhealthy pressures 2Studies: Children obese due to a host of unhealthy pressures 3Studies: Children obese due to a host of unhealthy pressures 4
(Date:12/22/2014)... 22, 2014 /PRNewswire/ - RepliCel Life Sciences Inc. (OTCQB: ... focused on the development of autologous cell therapies, announced ... University of Calgary in conjunction with co-authors from Kyoto ... validates the company,s ongoing clinical research using dermal sheath ... baldness. The paper entitled " Hair Follicle ...
(Date:12/22/2014)... The American Journal of Hematology/Oncology, ... and editorials addressing developments and pathways related to ... provocative article exploring the role of follicle-stimulating hormone ... of prostate cancer. , The article references ... that there could be a connection to prostate ...
(Date:12/19/2014)... December 19, 2014 Charm Sciences is ... for the Detection of Aflatoxin M1 in raw commingled ... independent third party validation. The peer reviewed report of ... the Institute for Agricultural and Fisheries Research (ILVO-T&V) has ... , Aflatoxin B1, the most toxic aflatoxin and a ...
(Date:12/19/2014)... , Dec. 19, 2014 Bina Technologies, Inc. (Bina, ... today that they have been acquired by Roche (SIX: ... a privately held company that provides a big data ... sequencing (NGS) data for the academic and translational research ... Unit, and will continue to focus on development of ...
Breaking Biology Technology:Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 2Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 4Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 5Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 4Charm Sciences Achieves Independent Validation of First 15 Minute Quantitative Screening Method for Aflatoxin M1 2Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3
... , , , ... reported results for the quarter ended June 30, 2009. Revenue for the ... June 30, 2008. Revenue for the six months ended June 30, 2009 ... , , Dendreon,s total operating expenses for the second ...
... ... Spectrum Chemicals & Laboratory Products (Spectrum) announced the ... will increase productivity and lessen injuries due to repetitive hand ... and is engineered to improve throughput in laboratories performing chromatography, ...
... 10 deCODE genetics,(Nasdaq: DCGN ) today announced ... 2009. A conference call to discuss these results and,recent ... tomorrow,Tuesday, August 11, at 8:00am Eastern Daylight Time/12 noon ... The financial results presented below reflect deCODE,s strategic ...
Cached Biology Technology:Dendreon Reports Second Quarter 2009 Financial Results 2Dendreon Reports Second Quarter 2009 Financial Results 3Dendreon Reports Second Quarter 2009 Financial Results 4Dendreon Reports Second Quarter 2009 Financial Results 5Dendreon Reports Second Quarter 2009 Financial Results 6Spectrum Announces New Distribution of AC-Powered Tool for Crimping and Decapping of Laboratory Vials - The CRIMPenstein™ 2deCODE genetics Announces Second Quarter 2009 Financial Results 2deCODE genetics Announces Second Quarter 2009 Financial Results 3deCODE genetics Announces Second Quarter 2009 Financial Results 4deCODE genetics Announces Second Quarter 2009 Financial Results 5deCODE genetics Announces Second Quarter 2009 Financial Results 6deCODE genetics Announces Second Quarter 2009 Financial Results 7deCODE genetics Announces Second Quarter 2009 Financial Results 8deCODE genetics Announces Second Quarter 2009 Financial Results 9deCODE genetics Announces Second Quarter 2009 Financial Results 10
RayBio L Series 507: RayBio Label-based Antibody Array I (1 glass slide with 2 subarrays) Class: Antibody Array Products Product Group: Antibody Array...
X-Gal, 1 g. 5-Bromo-4-chloro-3-indolyl-b-d-galactoside.Histochemical substrate for b-galactosidase, used in blue/white screening.Store at -20 C. Protect from moisture. Category: Nucleotides & Enzymes...
Blimp-1 (H-150)...
Rabbit polyclonal to Kallikrein 1 ( Abpromise for all tested applications). Antigen: Full length native kallikrein from tissue (Human) Entrez Gene ID: 3816 Swiss Protein ID: P06870...
Biology Products: