Navigation Links
Plants' oil-desaturating enzymes pair up to channel metabolites
Date:5/9/2014

s) of Arabidopsis, a common experimental plant.

Ying Lou, a postdoctoral research fellow working in Shanklin's lab, used several independent methods of bi-molecular complementation-methods that produce a signal if two test proteins come together-to establish which desaturases interact with themselves or others.

The scientists found that all the plant membrane desaturases they examined are capable of forming self-associating dimers in plant cells-pairings of two identical desaturase enzyme molecules. They also found that certain desaturases with different functions could also pair up, but others could not.

"The naturally pairing enzymes turn out to have interesting patterns," Shanklin said. "They are found in the same subcellular locations within the cell, and are involved in subsequent steps of the same metabolic pathway, suggesting a physiological driver for the observed pairings.

"Other pairings between very similar desaturases from different locations that we expected to pair up didn't," he added.

To test the idea that the paired enzymes were working together, the scientists conducted another series of experiments called metabolic flux analysis, drawing on Brookhaven biochemist Jorg Schwender's expertise. This method follows mass-labeled compounds through the various reaction pathways.

"Think of a city map with lots of ways to get from A to B. This method traces how many molecules travel along each route," Schwender said.

The analysis showed that one of the natural enzyme pairings performed two steps of a particular metabolic process without releasing an intermediate product.

"This was clear evidence that these two linked enzymes were working in concert to channel metabolites through this metabolic pathway in an efficient manner in living plant cells," Shanklin said. "Our findings suggest genetic techniques may be used to engineer these kinds of interactions into other desaturase enzymes-in
'/>"/>

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Light-sensitive eyes in plants
2. Putting the endoparasitic plants Apodanthaceae on the map
3. Plants send out signals attracting harmful bacteria, MU study finds
4. Plants with dormant seeds give rise to more species
5. Genetically modified tobacco plants as an alternative for producing bioethanol
6. Berkeley graduate student brings extinct plants to life
7. Tracking sugar movement in plants
8. New gel to promote bone growth on implants used in surgical procedures
9. Planning and building products and production plants simultaneously
10. First evidence of plants evolving weaponry to compete in the struggle for selection
11. Study finds forest corridors help plants disperse their seeds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Plants' oil-desaturating enzymes pair up to channel metabolites
(Date:9/18/2014)... Wis. No matter how many times it,s ... social, communicating creatures. , But by using ... organisms radically alter their behavior to suit their ... of them are present, and act accordingly. , ... millions, it may change from innocuous to pathogenic, ...
(Date:9/18/2014)... acquire and creatively manipulate spoken language is unique to ... 6 million years of human evolution to make this ... candidate gene we now have," says Wolfgang Enard, Professor ... efforts to understand the molecular biological basis of language ... results of his latest study, undertaken in collaboration with ...
(Date:9/18/2014)... their colleagues have built the first smartphone app ... and behavioral trends. In other words, your smartphone ... you don,t -- and how that affects you. ... stress, depression and loneliness to their academic performance, ... for example, to monitor mental health, trigger ...
Breaking Biology News(10 mins):Researchers study vital 'on/off switches' that control when bacteria turn deadly 2Researchers study vital 'on/off switches' that control when bacteria turn deadly 3Language evolution: Quicker on the uptake 2Language evolution: Quicker on the uptake 3New Dartmouth smartphone app reveals users' mental health, performance, behavior 2New Dartmouth smartphone app reveals users' mental health, performance, behavior 3New Dartmouth smartphone app reveals users' mental health, performance, behavior 4
... first time in humans, scientists have found early indicators ... by repetitive motion. , Their findings could someday ... such as carpal tunnel syndrome and tendonitis. , ... Barr and Mary Barbe and their doctoral student, Stephen ...
... develop insidiously and are generally discovered when the memory ... Institutet shows, however, that approaching Alzheimer's can be detected ... Dementia involves a serious deterioration of mental function caused ... of which Alzheimer's is the most common. Although there ...
... study in Journal of Personality shows that selfless and ... specifically religious environment. After studying the behavior of adult ... tended to appear together, the correlation was due to ... author Laura Koenig, the popular idea that religious individuals ...
Cached Biology News:Red flag for repetitive stress injuries identified for first time in humans 2Gene tests and brain imaging reveal early dementia 2
(Date:9/19/2014)... 2014  An entire month is dedicated to one ... Charcot-Marie-Tooth disease (CMT) – a debilitating neuromuscular disease affecting ... atrophy, weakness, and foot and hand deformities. CMT affects ... CMT is a progressive disease, and over time patients ... devices such as leg braces, wheelchairs and scooters to ...
(Date:9/19/2014)... 2014 Barnhardt Manufacturing Company ... its Organic Cotton . The USDA Certified Biobased ... biobased ingredients meets or exceeds levels set by USDA. ... whole or in significant part of agricultural, forestry, or ... Organic cotton to be immediately identified as a USDA ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 Bipartisan passage ... a bill designed to stimulate development and commercialization of ... being praised by leaders of SPIE, the international ... Revitalizing American Manufacturing and Innovation (RAMI) Act, now moves ... authors have said they are optimistic that it will ...
(Date:9/18/2014)... 18, 2014  Health Enhancement Products, Inc. (OTCQB: HEPI), a ... bioactive compounds and metabolic processes, is pleased to announce the ... directors. Ms. Nola E. Masterson , a ... board effective September 17, 2014. "We,re very ... our board," states Andrew Dahl , President and CEO. ...
Breaking Biology Technology:September is Charcot-Marie-Tooth (CMT) Awareness Month - Scheduled events, activities and important partnerships announced throughout the month! 2Barnhardt Manufacturing Company Earns USDA Certified Biobased Product Certification and Label for Organic Cotton 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3Health Enhancement Announces New Board Member In Advance Of Annual Shareholder Meeting 2
... Inc. today announced,the first single port laparoscopic removal ... Drs. Anthony Discuillo and Christopher Awtry performed the ... AirSeal System creates an,invisible barrier that does not ... to the cavity without loosing intra-abdominal pressure,enabling surgeons ...
... 7 Advanced Life Sciences,Holdings, Inc. (Nasdaq: ... development and commercialization of novel drugs in the,therapeutic ... its financial results for the first quarter ended ... shareholders for the three months ended,March 31, 2008 ...
... a strong,pharmaceutical industry is a key issue in ... Gangwon Province and YuYu Inc.,intend to collaborate and ... Standard (ISS), Inc., will be formed to develop ... will meet,international Good Laboratory Practices (GLP) standards., ...
Cached Biology Technology:SurgiQuest Announces First Single Port Procedure for Ovary Removal Using AirSeal(TM) Access System 2Advanced Life Sciences Announces First Quarter 2008 Financial Results 2Advanced Life Sciences Announces First Quarter 2008 Financial Results 3Advanced Life Sciences Announces First Quarter 2008 Financial Results 4Advanced Life Sciences Announces First Quarter 2008 Financial Results 5Advanced Life Sciences Announces First Quarter 2008 Financial Results 6Advanced Life Sciences Announces First Quarter 2008 Financial Results 7Advanced Life Sciences Announces First Quarter 2008 Financial Results 8Advanced Life Sciences Announces First Quarter 2008 Financial Results 9Battelle Collaborating With Korean Partners to Advance Energy Efficiency and Health and Life Sciences Initiatives in Korea 2
...
Mouse monoclonal antibody raised against a partial recombinant ARHGEF11. NCBI Entrez Gene ID = ARHGEF11...
... Channel Cell Lines ,High Quality, Functionally-Validated, Ion ... well known for having a critical role ... have a key function in pain, CNS ... channels have been investigated in therapeutic areas, ...
Mouse monoclonal antibody raised against a partial recombinant TTC3. NCBI Entrez Gene ID = TTC3...
Biology Products: