Navigation Links
Plants cut the mustard for basic discoveries in metabolism
Date:2/5/2013

LA JOLLA, CA----You might think you have nothing in common with mustard except hotdogs. Yet based on research in a plant from the mustard family, Salk scientists have discovered a possible explanation for how organisms, including humans, directly regulate chemical reactions that quickly adjust the growth of organs. These findings overturn conventional views of how different body parts coordinate their growth, shedding light on the development of more productive plants and new therapies for metabolic diseases.

Metabolism refers to all the chemical reactions in the body that drive the basic processes of life: birth, growth, reproduction, digestion, sensing and so on. These reactions are orchestrated and quickened by molecular machines called enzymes. Until now, it was believed that each metabolic function required an entirely separate enzyme pathway. Further complicating the picture, scientists focused almost exclusively on genes switching on and off as the means by which each step in the pathway was regulated, roughly analogous to waiting for a part to be ordered then manufactured before the engine can run.

In a paper in this week's Nature Chemical Biology, Salk scientists and Howard Hughes Medical Institute Investigators Joanne Chory and Joseph P. Noel and their colleagues show that metabolic steps can be much more streamlined and linked. Unexpectedly, two separate pathways originally thought to be controlled solely by gene switches can have enzyme canals between them, allowing them to quickly share abundant building blocks for two separate chemical messages known as hormones. These hormones are manufactured in one part of the body in response to changes in environment and quickly alter growth in other parts. Many times, at least two hormones are needed to quickly adjust growth of different tissues in response to a single event.

"Genes are the instruction manuals for how cells build specific enzymes in a pathway, but if you hav
'/>"/>

Contact: Andy Hoang
AHoang@salk.edu
619-861-5811
Salk Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. How plants sense gravity -- a new look at the roles of genetics and the cytoskeleton
2. Can plants be altruistic? You bet, says new CU-Boulder-led study
3. Plants adapt to drought but limits are looming, study finds
4. How the protein transport machinery in the chloroplasts of higher plants developed
5. Giant tobacco plants that stay young forever
6. Invading species can extinguish native plants despite recent reports
7. Study finds Jurassic ecosystems were similar to modern: Animals flourish among lush plants
8. Improving DNA amplification from problematic plants
9. Discovery of Africa moth species important for agriculture, controlling invasive plants
10. Pulverized rocks used to strip CO2 from large emitting plants
11. Researchers investigate impacts of climate change on rare tropical plants
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Plants cut the mustard for basic discoveries in metabolism
(Date:8/21/2014)... North Carolina State University have developed a novel and ... has applications for creating new materials as well as ... new technique allows us to model much larger and ... more quickly," says Nan Li, lead author of a ... NC State,s Department of Materials Science and Engineering. "This ...
(Date:8/20/2014)... study of 158 pregnant teenagers in Rochester, NY, nearly ... consumption of ice, cornstarch, vacuum dust, baby powder and ... study. , Moreover, such teens had significantly lower iron ... nonfood substances. , Pregnant teens, regardless of pica, are ... to iron deficiency and anemia. Low iron in pregnant ...
(Date:8/20/2014)... 20, 2014 /CNW/ -  Issue Serious ... quickly become life threatening for some children.    ... million Canadians have food allergies and this number may be ... children are estimated to have food allergies.  ... irritations and hives to breathing difficulties and loss of consciousness. ...
Breaking Biology News(10 mins):Researchers develop models to study polyelectrolytes, including DNA and RNA 2Pica in pregnant teens linked to low iron 2Information Update - Allergens and food safety at school - What's in your child's lunch? 2Information Update - Allergens and food safety at school - What's in your child's lunch? 3
... R.I. [Brown University] Scientists have long known that ... clear is how the brain processes more complex and ... 28, 2010) in the journal Neuron , a ... of CaliforniaBerkeley tested whether the frontal lobe has the ...
... divided into three sessions: the past, present and future ... and ethics related to PGD. The target audience ... physicians, nurses, embryologists, patient advocacy groups and patients themselves. ... event here: http://www.eshre.eu/page.aspx/905 You are welcome ...
... released this week in The Lancet Infectious Diseases ... a bacterial infection that causes pneumonia, meningitis and sepsis ... disease, a blood disorder prevalent in African children that ... The study underscores the critical need for use of ...
Cached Biology News:Complex brain functions help adapt to new situations and stimuli 2Vaccines preventing pneumococcal disease protect African children with sickle-cell disease 2Vaccines preventing pneumococcal disease protect African children with sickle-cell disease 3
(Date:8/21/2014)... Boston, MA (PRWEB) August 21, 2014 ... collaboration company, has been recognized as one of ... 500 | 5000 magazine for the 2nd consecutive ... on its 33rd annual Inc. 500|5000, an exclusive ... list represents the most comprehensive look at the ...
(Date:8/20/2014)... For the first time, chemists have succeeded in measuring ... time resolution. The study reveals how vibration of a ... groups. , The study was performed at the ... from the University of Jyvskyl works as a visiting ... in the study. The second team was lead by ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 The ... is being held on October 29-30 in San Francisco, ... industry, academic and government researchers and clinicians focused on ... space. , In the twelve years since the ... therapies have been introduced with pharmacogenetic information in the ...
(Date:8/20/2014)... Sofia, Bulgaria (PRWEB) August 20, 2014 ... was released today including improvements to the ... rates and connectors for Lucene, SOLR and Elasticsearch. ... change for this high performance triplestore – GraphDB™ ... organizations interested in deploying the only mature enterprise ...
Breaking Biology Technology:SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Seeing a molecule breathe 26th Annual Personalized and Precision Medicine Conference Bringing Together Thought Leaders to Discuss Clinical Implementation, Dx Reimbursement, Big Data, and Sequencing 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4
... , , ... May 11 /PRNewswire-FirstCall/ - Quest PharmaTech Inc. (TSX-V: QPT) ... for the treatment of cancer, today announced the dosing of the ... with SL052 Photodynamic Therapy in prostate cancer patients. The study will ...
... HARBIN, China , May 11 /PRNewswire-Asia-FirstCall/ -- ... Company") (Nasdaq: CSKI ), a leading,fully integrated pharmaceutical company ... ("PRC"), today announced the Company attended,the 107th China Import and ... May 1st,to 5th, 2010 and generated significant interest from ...
... N30 Pharma (N30), a biopharmaceutical company focused on the discovery and development of ... that it has completed a $10 million financing and expanded its Board ... Joining the Company,s Board of Directors ... , , ...
Cached Biology Technology:Quest PharmaTech Announces Dosing Of First Patient In Its Prostate Cancer Clinical Trial 2Quest PharmaTech Announces Dosing Of First Patient In Its Prostate Cancer Clinical Trial 3China Sky One Medical Attended Import and Export Fair to Enhance International Growth Opportunity 2China Sky One Medical Attended Import and Export Fair to Enhance International Growth Opportunity 3China Sky One Medical Attended Import and Export Fair to Enhance International Growth Opportunity 4
UBC13 Antibody...
HLA II DG+DR+DP Monoclonal Antibody, Purified, Unconjugated, Clone: IQU9 This antibody is specific for the monomorphic determinant of the HLA Class II beta chains of the human MHC (28 kDa)....
Phenytoin-BSA Isolated IgY DFc Drug...
Tropomyosin 4 [Tm4]...
Biology Products: