Navigation Links
Plants cut the mustard for basic discoveries in metabolism
Date:2/5/2013

LA JOLLA, CA----You might think you have nothing in common with mustard except hotdogs. Yet based on research in a plant from the mustard family, Salk scientists have discovered a possible explanation for how organisms, including humans, directly regulate chemical reactions that quickly adjust the growth of organs. These findings overturn conventional views of how different body parts coordinate their growth, shedding light on the development of more productive plants and new therapies for metabolic diseases.

Metabolism refers to all the chemical reactions in the body that drive the basic processes of life: birth, growth, reproduction, digestion, sensing and so on. These reactions are orchestrated and quickened by molecular machines called enzymes. Until now, it was believed that each metabolic function required an entirely separate enzyme pathway. Further complicating the picture, scientists focused almost exclusively on genes switching on and off as the means by which each step in the pathway was regulated, roughly analogous to waiting for a part to be ordered then manufactured before the engine can run.

In a paper in this week's Nature Chemical Biology, Salk scientists and Howard Hughes Medical Institute Investigators Joanne Chory and Joseph P. Noel and their colleagues show that metabolic steps can be much more streamlined and linked. Unexpectedly, two separate pathways originally thought to be controlled solely by gene switches can have enzyme canals between them, allowing them to quickly share abundant building blocks for two separate chemical messages known as hormones. These hormones are manufactured in one part of the body in response to changes in environment and quickly alter growth in other parts. Many times, at least two hormones are needed to quickly adjust growth of different tissues in response to a single event.

"Genes are the instruction manuals for how cells build specific enzymes in a pathway, but if you hav
'/>"/>

Contact: Andy Hoang
AHoang@salk.edu
619-861-5811
Salk Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. How plants sense gravity -- a new look at the roles of genetics and the cytoskeleton
2. Can plants be altruistic? You bet, says new CU-Boulder-led study
3. Plants adapt to drought but limits are looming, study finds
4. How the protein transport machinery in the chloroplasts of higher plants developed
5. Giant tobacco plants that stay young forever
6. Invading species can extinguish native plants despite recent reports
7. Study finds Jurassic ecosystems were similar to modern: Animals flourish among lush plants
8. Improving DNA amplification from problematic plants
9. Discovery of Africa moth species important for agriculture, controlling invasive plants
10. Pulverized rocks used to strip CO2 from large emitting plants
11. Researchers investigate impacts of climate change on rare tropical plants
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Plants cut the mustard for basic discoveries in metabolism
(Date:12/17/2014)... DUBLIN , Dec. 16, 2014 Research ... announced the addition of the "Global Chemical ... http://photos.prnewswire.com/prnh/20130307/600769 ... is the increasing demand for medical sensors in ... patient data for quick and correct diagnosis during ...
(Date:12/11/2014)... 2014  That blood pressure plays a role in human ... the medical term for high blood pressure – was first ... inflatable cuff that,s used in measuring blood pressure was invented ... new about hypertension, its triggers and its effects. In fact, ... and the best ways to treat it. For ...
(Date:12/10/2014)... DIEGO , Dec. 9, 2014 CIE ... collaboration catalyst that provides the connective tissue that enhances ... enabling them to easily share client-level information; earned a ... to expand to organizations serving seniors aging in community ... Diego" partner on December 11 th 4-6p. ...
Breaking Biology News(10 mins):Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... artificial cells manufactured using microprinting may one day serve ... biotechnology and biosensing applications, according to a team of ... allow researchers to explore actions that take place at ... is going on inside that it is extremely complex," ...
... change tend to focus on comprehensive, emissions-focused measures: a ... tax on all carbon emissions. But a new study ... involving separate targeting of energy choices and energy ... important role in achieving emission reductions. The new ...
... of ultrathin graphene combined with polyurethane paint meant for cars ... to scientists at Rice University. The Rice lab ... the compound to protect marine and airborne radars with a ... The research was published this week in the American ...
Cached Biology News:Microprinting leads to low-cost artificial cells 2Study finds piece-by-piece approach to emissions policies can be effective 2Study finds piece-by-piece approach to emissions policies can be effective 3Graphene nanoribbons an ice-melting coat for radar 2Graphene nanoribbons an ice-melting coat for radar 3
(Date:12/19/2014)... , Dec. 18, 2014 Relmada Therapeutics, Inc. ... the treatment of chronic pain, announced the results of ... "This was a transformational year in Relmada,s history ... for our company," said Sergio Traversa , chief ... have executed on key financial, human resource and clinical ...
(Date:12/17/2014)... Based on the revenues gained from surgical imaging ... by four major players contributing to approximately 74% ... GE Healthcare (U.K.), Siemens AG (Germany), Philips (Netherlands), ... Copy at http://www.marketsandmarkets.com/Market-Reports/surgical-imaging-market-210534462.html , The leading ... its strong product portfolio, which includes its flagship ...
(Date:12/17/2014)... 2014 Achim Noack has been named ... Group. In this position, Noack will assist Jerry Stoller, ... develop marketing strategy and supervise global marketing management and ... has tremendous knowledge and experience in the crop protection ... experience and innovative thinking will be a great asset ...
(Date:12/17/2014)... 17, 2014 Once more, EMAAR ... larger packaged waste water treatment plant to phase one ... City (KAEC). Two years ago Bioshaft successfully supplied and ... serving two residential towers with an occupancy of 900 ... quarter million gallons per day and was signed on ...
Breaking Biology Technology:Relmada Therapeutics Announces Results of Annual Shareholders Meeting 2Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 2Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 3Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 4Achim Noack Joins Stoller Group as Global Vice President of Marketing and Administration 2
... May 3, 2012 PDL BioPharma, Inc. (PDL) (NASDAQ: ... quarter ended March 31, 2012. (Logo:  http://photos.prnewswire.com/prnh/20110822/SF55808LOGO ) ... 2012 increased five percent over the same period of 2011. ... million, compared to $83.3 million for the same period of ...
... Having headquarters in one of the  world,s largest democracies ... sought after exporters of Hospital Furniture and Orthopedic Implants. Product ... are some of the unique selling propositions of the organization. ... for quite a few years now. We are very happy ...
... 3, 2012  Discovery Laboratories, Inc. (Nasdaq: DSCO ... new standard in respiratory critical care, today reports financial ... The Company will host a conference call this morning ... Key financial information includes: , For ...
Cached Biology Technology:PDL BioPharma Announces First Quarter 2012 Financial Results 2PDL BioPharma Announces First Quarter 2012 Financial Results 3PDL BioPharma Announces First Quarter 2012 Financial Results 4PDL BioPharma Announces First Quarter 2012 Financial Results 5Customer Satisfaction, A key to Success: Narang Medical Limited 2Discovery Labs Reports First Quarter 2012 Financial Results 2Discovery Labs Reports First Quarter 2012 Financial Results 3Discovery Labs Reports First Quarter 2012 Financial Results 4Discovery Labs Reports First Quarter 2012 Financial Results 5Discovery Labs Reports First Quarter 2012 Financial Results 6Discovery Labs Reports First Quarter 2012 Financial Results 7Discovery Labs Reports First Quarter 2012 Financial Results 8Discovery Labs Reports First Quarter 2012 Financial Results 9Discovery Labs Reports First Quarter 2012 Financial Results 10Discovery Labs Reports First Quarter 2012 Financial Results 11
6-carboxy-2',4,4',5',7,7'-hexachlorofluorescein, succinimidyl ester (6-HEX, SE) *single isomer*...
... ZMD.473. Immunogen: Synthetic peptide derived ... mouse junctophilin-2. Specificity: Specific for ... (positive controls: mouse skeletal muscle homogenates ... Applications: Western blotting Immunohistochemistry(froz) ImmunofluorescenceStorage: Store ...
Laminin gamma-2 (G-16)...
ABIN-2 Polyclonal Ab 100 ug rabbit polyclonal antibody. Detects ABIN-2 in human/mouse. Tested in WB....
Biology Products: