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Plant oil may hold key to reducing obesity-related medical issues, MU researcher finds
Date:3/23/2011

or potential use in humans," Perfield said. "Reducing belly fat is a key to reducing the incidence of serious disease, and this oil could have a future as a nutritional supplement."

To study the compound, Perfield added sterculic oil to the feed of rats that are genetically disposed to have a high amount of abdominal fat. He tested the rats over the course of 13 weeks and found that rats given a diet supplemented with sterulic oil had less abdominal fat and a decreased likelihood of developing diabetes. Perfield gave the rats a relatively small dose of oil each day, comparable to giving three grams to a 250-pound human.

Belly fat, clinically known as intra-abdominal fat, is between internal organs and the torso. Intra-abdominal fat is composed of "adipose" deposits. Unusually high adipose levels trigger health problems that may induce insulin resistance, which causes the body to have difficulty maintaining blood sugar levels. Initially, the body is able to compensate by producing more insulin, but eventually the pancreas is unable to produce enough insulin, thus increasing excess sugar in the bloodstream and setting the stage for diabetes, cardiovascular disease and other obesity-associated health disorders.

Perfield plans to conduct further studies of sterulic oil in hopes of developing a natural nutritional supplement. He says future research will focus on the effectiveness of the oil in humans, as well as any side effects.

"The oil from this seed is very similar to other vegetable oils," Perfield said. "It shares many of the same chemical properties, which could allow it to be easily substituted with other oils. While eating the seed directly may be possible, it's easier to control the amount of oil if you extract it directly."


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Contact: Christian Basi
BasiC@missouri.edu
573-882-4430
University of Missouri-Columbia
Source:Eurekalert  

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