Navigation Links
Plant clock gene also works in human cells
Date:12/1/2010

A gene that controls part of the 'tick tock' in a plant's circadian clock has been identified by UC Davis researchers. And not only is the plant gene very similar to one in humans, but the human gene can work in plant cells -- and vice versa. The research is published this week in the journal Proceedings of the National Academy of Sciences.

"It's surprising to find a clock gene that is performing the same function across such widely unrelated groups," said Stacey Harmer, associate professor of plant biology in the UC Davis College of Biological Sciences and senior author on the paper.

Major groups of living things -- plants, animals and fungi -- all have circadian clocks that work in similar ways but are built from different pieces, Harmer said. The newly identified gene is an exception to that.

Harmer and UC Davis postdoctoral scholar Matthew Jones, with colleagues at Rice University in Houston and the Salk Institute for Biological Studies in La Jolla, identified the "Jumonji-containing domain 5 gene," or JMJD5, from the lab plant Arabidopsis by screening existing databases for genes that were switched on along with the central plant clock gene, TOC1.

JMJD5 stood out. The protein made by the gene can carry out chemical modification of the histone proteins around which DNA is wrapped, and can likely regulate how genes are turned on and off -- potentially making it part of a clock oscillator.

When Harmer and colleagues made Arabidopsis plants with a deficient gene, they found that the plants' in-built circadian clock ran fast.

A similar gene is found in humans, and human cells with a deficiency in this gene also have a fast-running clock. When the researchers inserted the plant gene into the defective human cells, they could set the clock back to normal -- and the human gene could do the same trick in plant seedlings.

Because the rest of the clock genes are quite different betwee
'/>"/>

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis
Source:Eurekalert

Page: 1 2

Related biology news :

1. MU plant genome research receives $3 million boost from National Science Foundation
2. How pathogens hijack host plants
3. Reading the signs: Plants and animals found common ground in response to microbial threats
4. In fending off diseases, plants and animals are much the same, research shows
5. The lifeblood of leaves: Vein networks control plant patterns
6. Nanotechnology: A dead end for plant cells?
7. Budding research links climate change and earlier flowering plants
8. Using plants against soils contaminated with arsenic
9. Change in temperature uncovers genetic cross talk in plant immunity
10. Biochemistry of how plants resist insect attack determined
11. New research changes understanding of C4 plant evolution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/8/2015)... , April 8, 2015  Infinisource, a ... and services, and Morpho, a leading supplier of ... to produce the market,s most advanced biometrically-enabled time ... iSolved NXG time clock is setting a bold, ... labor data for the small and mid-size employer. ...
(Date:4/2/2015)... April 2, 2015 In ... by far outperforms the strongest competitors, showing outstanding ... accuracy, the system is capable of a throughput ... proves up to be ten times faster than ... runner-up performance.      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ...
(Date:4/2/2015)... According to preliminary estimates Fingerprint ... higher than 125 MSEK. This exceeds the guidance provided ... revenues for Q1 2015 would be in line with ... 2014. The operating result for the first quarter is ... report will as previously communicated be published on May ...
Breaking Biology News(10 mins):iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Fingerprint Cards Revises Revenues for Q1 2015 2
... enhanced the abilities of the molecules they are creating ... molecular complexes enter cancer cells and, when signaled, deliver ... new supermolecules have more units that will absorb light ... frequencies that can be included and excluded as signals ...
... DNA isn't just for storing genetic codes any more. ... into larger structures -- scientists have been using it ... even working mechanical devices. , Now Cornell University researchers ... could be used for drug delivery and as containers ...
... have become invaluable decision-making tools for public health ... epidemic of 2001, models can be useful in ... of an infection and they can allow the ... models make implicit assumptions that may systematically bias ...
Cached Biology News:Virginia Tech group adds tools to DNA-targeted anti-cancer drugs 2Virginia Tech group adds tools to DNA-targeted anti-cancer drugs 3Self-assembled DNA buckyballs for drug delivery 2Self-assembled DNA buckyballs for drug delivery 3Understanding biases in epidemic models important when making public health predictions 2
(Date:4/24/2015)... Seoul Semiconductor announced the expansion of ... the lighting market. In recent months, there ... in emerging markets such as Russia, South America, ... applications such as streetlight and area lighting, tunnel ... launched in 2005 the Acrich technology from Seoul ...
(Date:4/23/2015)... April 23, 2015 Athena San Diego, ... of executive women in San Diego’s technology and life ... Annual Pinnacle Awards at their Gala on April 30, ... Register now at http://athenasd.org/events/ , The Pinnacle ... Athena San Diego vision of fostering networking, risk taking ...
(Date:4/23/2015)... 23, 2015 /CNW/ - A new and innovative service ... North America,s largest packaging ... Silver in the "Sustainability, service" category of the ... "Competitor Comparison" is a service that scores clients, ... Global peers. This benchmarking process shows clients how ...
(Date:4/23/2015)... (PRWEB) April 23, 2015 Six ... region on April 4-17 as part of the ... the fourth group of biotechnology startups to participate ... Nizhny Novgorod (UNN) and the University of Maryland ... ties between their respective universities in the biomedical ...
Breaking Biology Technology:Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2Athena Pinnacle Awards to Honor Executives, Corporations and Educators Working to Promote Women Leaders 2U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 2U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 3U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 4
... NeoStem, Inc.,(NYSE Alternext US: NBS), which is pioneering the pre-disease ... medical need,today announced that it has completed an above market ... $1.25 per unit with each unit,consisting of one share of ... stock at $1.75 per share. , ...
... SAN FRANCISCO, Calif., Dec. 3 Portola,Pharmaceuticals, a ... in cardiovascular disease, inflammatory disease,and cancer, today announced ... novel,compounds that inhibit spleen tyrosine kinase (Syk) and ... presented at the annual meeting of the,American Society ...
... , , QUEBEC CITY, ... AEZS ; TSX: AEZ), a global biopharmaceutical company ... has completed the transaction under the previously announced purchase ... ("CHRP") relating to AEterna Zentaris, rights to royalties on ...
Cached Biology Technology:NeoStem Completes $500,000 Private Placement With Strategic Investor 2NeoStem Completes $500,000 Private Placement With Strategic Investor 3Portola Data on Its Novel Syk Inhibitors and Novel Universal Factor Xa Inhibitor Antidote to be Presented at 2008 American Society of Hematology (ASH) Meeting 2Portola Data on Its Novel Syk Inhibitors and Novel Universal Factor Xa Inhibitor Antidote to be Presented at 2008 American Society of Hematology (ASH) Meeting 3AEterna Zentaris Closes Sale of Cetrotide(R) Royalty Stream for $52.5 Million to Cowen Healthcare Royalty Partners 2AEterna Zentaris Closes Sale of Cetrotide(R) Royalty Stream for $52.5 Million to Cowen Healthcare Royalty Partners 3
Applications: Western blotting ...
...
... chemiluminescence efficiencies and the chemistry of light ... added benefit that they require simple triggering ... signal. This benefit has been exploited to ... These compounds can also be easily modified ...
ssDNA from PCR DNA in less than 1 hour. No gels, columns, or slurries. Sequence from high quality ssDNA: clearer reads, longer runs....
Biology Products: