Navigation Links
Pitt team recreates brain cell networks with new view of activity behind memory formation
Date:5/25/2011

natural network. The researchers disabled the cells' inhibitory response and then excited the neurons with an electrical pulse.

Zeringue and his colleagues were able to sustain the resulting burst of network activity for up to what in neuronal time is 12 long seconds. Compared to the natural duration of .25 seconds at most, the model's 12 seconds permitted an extensive observation of how the neurons transmitted and held the electrical charge, Zeringue said.

Unraveling the mechanics of this network communication is key to understanding the cellular and molecular basis of memory creation, Zeringue said. The format developed at Pitt makes neural networks more accessible for experimentation. For instance, the team found that when activity in one neuron is suppressed, the others respond with greater excitement.

"We can look at neurons as individuals, but that doesn't reveal a lot," Zeringue said. "Neurons are more connected and interdependent than any other cell in the body. Just because we know how one neuron reacts to something, a whole network can react not only differently, but sometimes in the complete opposite manner predicted."

Zeringue will next work to understand the underlying factors that govern network communication and stimulation, such as the various electrical pathways between cells and the genetic makeup of individual cells.


'/>"/>

Contact: Morgan Kelly
mekelly@pitt.edu
412-624-4356
University of Pittsburgh
Source:Eurekalert  

Page: 1 2

Related biology news :

1. CCNY-led interdisciplinary team recreates colonial hydrology
2. Penn biophysicists create new model for protein-cholesterol interactions in brain and muscle tissue
3. During exercise, the human brain shifts into high gear on alternative energy
4. Millisecond brain signals predict response to fast-acting antidepressant
5. Food for thought -- regulating energy supply to the brain during fasting
6. Risk and reward compete in brain
7. Brainy genes, not brawn, key to success on mussel beach
8. Brain-nourishing molecule may predict schizophrenia relapse
9. Brain structure provides key to unraveling function of bizarre dinosaur crests
10. MU brain imaging center provides research for autism, schizophrenia and Parkinsons disease
11. Key to function of dinosaur crests found in brain structure
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Pitt team recreates brain cell networks with new view of activity behind memory formation
(Date:8/27/2014)... basic research, a growing focus on translating discoveries ... have earned the Herbert Irving Comprehensive Cancer Center ... NewYork-Presbyterian Hospital an $18 million, five-year Cancer Center ... The grant renews the center,s status as one ... New York City and one of only three ...
(Date:8/27/2014)... trans-fats have largely succeeded in sidelining the use ... for its potential contributions to Americans, health conditions. ... the best way to assuage the nation,s insatiable ... Chemical & Engineering News (C&EN), the weekly ... In the article, Stephen Ritter, a senior correspondent ...
(Date:8/27/2014)... thought to be associated with outcomes after the ... of the patient, mechanism of injury, nerve injured, ... operation technique, and repair materials. However, despite numerous ... nerve injuries, there is no agreement regarding the ... dose-effect relationship of the predictors has not been ...
Breaking Biology News(10 mins):Herbert Irving Comprehensive Cancer Center awarded $18 million grant 2Herbert Irving Comprehensive Cancer Center awarded $18 million grant 3Herbert Irving Comprehensive Cancer Center awarded $18 million grant 4
... sciences professor Harris Lewin is a recipient of the ... with James R. Cook, of Washington State University. ... recipients in agriculture, chemistry, physics, mathematics, medicine and the ... significant discoveries" in the field of animal agriculture. ...
... from the Walter and Eliza Hall Institute have begun ... a key gene required for the process. The ... blood stem cells, unique ability to self-renew could give ... tissue repair, transplantation and other therapeutic applications. Professor ...
... This release is available in Spanish . ... refrigerators that an estimated 20 percent are lost to spoilage, ... with USDA,s Agricultural Research Service (ARS) are working with colleagues ... The research also may lead to tomatoes that taste better ...
Cached Biology News:Illinois professor awarded 2011 Wolf Prize in Agriculture 2Erg gene key to blood stem cell 'self-renewal' 2Finding a way to extend tomato shelf-life 2
(Date:8/26/2014)... what they believe is the thinnest-possible semiconductor, a ... only three atoms thick. , The University of ... single-layer semiconductor materials can be connected in an ... result could be the basis for next-generation flexible ... and solar technologies. , "Heterojunctions are fundamental elements ...
(Date:8/26/2014)... , Aug. 26, 2014 An analysis by ... of all Mers CoV virus strains has ... back to 2012.  This conservation and sharing of specific ... Synthetic Mers CoV Blocker-Vaccine™ candidate, as it did for the ... both of which have been found to be effective ...
(Date:8/26/2014)... added to the growing case for graphene being ... thing in the high-tech world by the two-dimensional ... of researchers led by a scientist with the ... Laboratory (Berkeley Lab) has reported the first experimental ... materials. The recorded charge transfer time clocked in ...
(Date:8/26/2014)... Ga. , Aug. 26, 2014  ViveBio, ... biological sample collection, stabilization and transportation, announced today ... Laboratory Procurement Services, LLC (LPS) of ... of products in the United States ... new class of ambient temperature dried biological specimen ...
Breaking Biology Technology:Scientists craft atomically seamless, thinnest-possible semiconductor junctions 2Competition for graphene 2ViveBio and Laboratory Procurement Services Sign Agreement for Distribution of the ViveST Line of Products 2
... Transgenomic, Inc. (OTC/BB: TBIO) today reported financial results for ... business update. Second Quarter Financial ResultsNet sales ... increase of 50 percent compared with $5.1 million for the ... 59 percent of net sales, compared with gross profit of ...
... BETHESDA, Md., Aug. 11, 2011 The American College ... new ACMG Online Live Learning Center , which ... health care professionals. This valuable, on-demand resource brings the ... live learning offerings such as the Genetics Review Course ...
... GNVC ) today announced that its Board of ... through the adoption of a new Rights Agreement. The new ... 2011, which is the date that GenVec,s existing Rights Agreement ... in connection with the expiration of the existing Rights Agreement ...
Cached Biology Technology:Transgenomic Reports Second Quarter Financial Results 2Transgenomic Reports Second Quarter Financial Results 3Transgenomic Reports Second Quarter Financial Results 4Transgenomic Reports Second Quarter Financial Results 5Transgenomic Reports Second Quarter Financial Results 6Transgenomic Reports Second Quarter Financial Results 7Transgenomic Reports Second Quarter Financial Results 8Transgenomic Reports Second Quarter Financial Results 9ACMG Announces New Online Live Learning Center: Will Bring Genetics and Genomics Education to Varied Health Professionals 2GenVec Renews Stockholder Rights Plan 2GenVec Renews Stockholder Rights Plan 3
ANTI S. ENT TOX BC2D...
Porcine Serum US Origin 6 Months or Older...
... PlusOne Silver Staining Kit, Protein, ... Heukeshoven and Dernick (1), the kit ... gel electrophoresis systems.Silver Staining Kit, Protein ... of proteins in polyacrylamide gels in ...
All serum is collected from adult animals aged 6 months or older. Certified U.S. orgin. Pricing: $35/unit for 1 - 10 units...
Biology Products: