Navigation Links
Pitt researchers net $5 million from NIH to explore better ways to grow cells
Date:9/25/2009

Mount Sinai School of Medicine, Stanford University, and the University of Pennsylvania.

Lagasse's work focuses on lymph nodes, which are important in responses to bacterial and viral infection and are found throughout the body. Even spread out, the total mass of the nodes makes them a feasible place to grow liver cells, for example, which must also be available in abundance and with ample blood flow to provide life-sustaining hepatic function, Lagasse said. His team will explore growing liver and other tissues in such "ectopic" sites, meaning outside of where it would normally reside. The same principle of using lymph nodes as a site for ectopic cell factories might work for replacing pancreas cells that make insulin for patients with diabetes or immune system T-cells for patients who have AIDS and other diseases of immunologic-impairment.

"Our regenerative medicine approach for healing damaged tissues and organs might not have moved forward without this new grant concept," Lagasse noted. "This funding supports assessment and rapid translation from the bench to the bedside of nontraditional treatments."

Banerjee will investigate the process through which embryonic stem cells become mature, organ-specific cells and how scientists can control that development. Using a bottom-up approach, Banerjee will cultivate stem cells into pancreatic cells, noting molecular-level information that could be integrated into dictating cell development, such as the influence of environmental factors and gene and protein networks.

"I want to take a completely different approach to addressing the complex process of cell development, which will potentially advance our understanding of regenerative medicine and stem cell bioengineering as a whole," Banerjee said.

Two Pitt researchers have received NIH Director's awards in the past. In 2007, Eva Szigethy, of the Children's Hospital of Pittsburgh of UPMC and an assistant professor of psychiatry
'/>"/>

Contact: Morgan Kelly
mekelly@pitt.edu
412-624-4356
University of Pittsburgh
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Researchers identify new brain pathway for regulating weight and bone mass
2. LSUHSC researchers working to prevent diabetic neuropathy
3. Nanoresearchers challenge dogma in protein transportation in cells
4. MDC researchers discover molecule responsible for axonal branching
5. Cybernetwork to help K-State researchers study tallgrass prairie, respond to global warming
6. Researchers prolong the half-life of biopharmaceutical proteins
7. WCMC-Q researchers unlock genetic secrets of date palm
8. Weeding out marijuana: Researchers close in on engineering recognizable, drug-free Cannabis plant
9. Dartmouth researchers get personal with genetics
10. Ecosystem researchers to hold science briefing for policymakers
11. UAB researchers looking for genetic predictors for suicide
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... to produce hydrogen sulfide in order to properly multiply ... from the Center for Craniofacial Molecular Biology at the ... Songtao Shi, principal investigator on the project, said the ... the flow of calcium ions. The essential ions activate ... or the creation of new bone tissue, and keeps ...
(Date:4/17/2014)... and fragmentation of forests in the Amazon help ... contributing to rapid and widespread forest loss during ... The findings show that forests in the Amazon ... coupled with forest fires lead to large-scale loss ... Balch, assistant professor of geography, Penn State. , ...
(Date:4/17/2014)... have detected new early-warning signs of the potential loss ... far-reaching implications for the diagnosis and treatment of diabetic ... Americans. , "We had not expected to see such ... said Ann Elsner, professor and associate dean in the ... study. "We set out to study the early signs, ...
Breaking Biology News(10 mins):Drought and fire in the Amazon lead to sharp increases in forest tree mortality 2Drought and fire in the Amazon lead to sharp increases in forest tree mortality 3New technique detects microscopic diabetes-related eye damage 2New technique detects microscopic diabetes-related eye damage 3
... NEW YORK, Dec. 14, 2010 Reportlinker.com announces that ... catalogue: Global Biochip Markets: Microarrays and ... INTRODUCTION  STUDY GOALS ... study was to determine the status of current and ...
... Sustainability is the theme for the 65th Annual International ... in Portland June 19 to 21. Hundreds of scientists, ... non-profit groups, and private industry will gather to discuss ... information about innovations in the field., "The theme of ...
... (June 10, 2011) The Academy of Natural Sciences ... FMC Corporation to help Philadelphia public middle school students and ... career opportunities in the sciences. The $25,000 grant from the ... Academy for some 800 6th through 8th graders and their ...
Cached Biology News:Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 2Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 3Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 4Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 5Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 6Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 7Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 8Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 9Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 10Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 11Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 12Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 13Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 14Reportlinker Adds Global Biochip Markets: Microarrays and Lab-on-a-Chip 15Grant funds science career days for Philadelphia public school students 2
(Date:1/15/2014)... Calif. (PRWEB) January 15, 2014 Cynvenio, ... and management through the genomic analysis of tumor cells ... Therapy Finder™, a web-based cancer decision support application powered ... option with Cynvenio’s ClearID™ genomic test, Therapy Finder will ...
(Date:1/15/2014)... Houston, TX (PRWEB) January 15, 2014 ... Alzheimer’s disease, and about 1 in 3 seniors will ... ( source ). These jaw-dropping figures have shocked many ... function and, hopefully, help prevent these tragic age-related cognitive ...
(Date:1/15/2014)... CA (PRWEB) January 15, 2014 ... research solutions, today announced that Lupin Limited, one of ... Freeslate’s CM Protégé PharmD System for high ... Mumbai, India, is focused on a wide range of ...
(Date:1/14/2014)... Histogen, Inc., a regenerative medicine company developing ... simulated embryonic conditions, today announced that they have entered ... for physician-dispensed aesthetic products containing Histogen’s proprietary multipotent cell ... an amendment to the existing license between Histogen and ...
Breaking Biology Technology:Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 3Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3
... Nov. 3, 2010 Sangamo BioSciences, Inc. ... has been awarded a total of $978,000 in grants ... Discovery Project Program. Under the recently ... section 48D of the Internal Revenue Code, cash grants ...
... ... ... var shortURL ... we need to grab the first one. for (var r in data.results) { first_result = data.results[r]; break; } for ...
... Mass., Nov. 2, 2010 Repligen Corporation (Nasdaq: ... quarter of fiscal year 2011, ended September 30, 2010. ... to total revenue of $5,421,000 for the second quarter ... 35%.  Bioprocessing product revenue for the second quarter was ...
Cached Biology Technology:Sangamo BioSciences Awarded Grants for the Development of Four ZFP Therapeutic® Programs 2Sangamo BioSciences Awarded Grants for the Development of Four ZFP Therapeutic® Programs 3IGEN NETWORKS ANNOUNCES THE APPOINTMENT OF TWO NEW MEMBERS TO THE ADVISORY BOARD 2IGEN NETWORKS ANNOUNCES THE APPOINTMENT OF TWO NEW MEMBERS TO THE ADVISORY BOARD 3IGEN NETWORKS ANNOUNCES THE APPOINTMENT OF TWO NEW MEMBERS TO THE ADVISORY BOARD 4IGEN NETWORKS ANNOUNCES THE APPOINTMENT OF TWO NEW MEMBERS TO THE ADVISORY BOARD 5IGEN NETWORKS ANNOUNCES THE APPOINTMENT OF TWO NEW MEMBERS TO THE ADVISORY BOARD 6IGEN NETWORKS ANNOUNCES THE APPOINTMENT OF TWO NEW MEMBERS TO THE ADVISORY BOARD 7IGEN NETWORKS ANNOUNCES THE APPOINTMENT OF TWO NEW MEMBERS TO THE ADVISORY BOARD 8IGEN NETWORKS ANNOUNCES THE APPOINTMENT OF TWO NEW MEMBERS TO THE ADVISORY BOARD 9Repligen Reports Second Quarter Fiscal Year 2011 Financial Results 2Repligen Reports Second Quarter Fiscal Year 2011 Financial Results 3Repligen Reports Second Quarter Fiscal Year 2011 Financial Results 4Repligen Reports Second Quarter Fiscal Year 2011 Financial Results 5Repligen Reports Second Quarter Fiscal Year 2011 Financial Results 6Repligen Reports Second Quarter Fiscal Year 2011 Financial Results 7
... CC1041 is a recombinant 177 amino ... Gly265 of mature human MT1-MMP. Produced ... of MT1-MMP purified from E. coli periplasm. ... catalytic domain is = 140 mU/mg, where ...
... mM sodium phosphate buffer, pH 6.5. Cathepsin ... a major lysosomal aspartyl protease in mammalian ... Overexpression of cathepsin D in human breast ... relapse and metastasis. Cathepsin D degrades extracellular ...
... in Refrigerated Vapor Trap Models RVT100, RVT400, ... Models UVS400, UVS400A and UVS800DDA., A non-corrosive, ... use for temperatures ranging from -105 to ... stability and does not evaporate. Far superior ...
Rat Cardiac Fibroblasts (RCF) (>500,000 cells)...
Biology Products: