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Pitt gets $12 million DoD contract for regenerative medicine treatment trials
Date:5/25/2010

Chair, Pitt Swanson School of Engineering; and Charles Sfeir, D.D.S., Ph.D., Pitt School of Dental Medicine

  • Evaluate the injection of human fibroblasts, a type of connective tissue cell, into contracted burn scars to soften the skin and allow greater freedom of movement; primary investigators J. Peter Rubin, M.D., Pitt School of Medicine, and Paul Kemp, Ph.D., founder, chief scientific officer and executive director, Intercytex

    Battlefield mortality has decreased from 30 percent in World War II to less than 10 percent in the conflicts of the present day, partly due to advances in medicine, surgery and trauma care. Still, injured soldiers are returning home with life-changing wounds, including finger and limb amputations that have doubled in rate since WWII.

    The OTT Initiative is funded by the Joint Improvised Explosive Device Defeat Organization (JIEDDO). The projects, if successful, could ultimately lead to interventions that also benefit civilians, noted Arthur S. Levine, M.D., senior vice chancellor for the health sciences and dean, School of Medicine, University of Pittsburgh.

    "Muscle loss, bone damage, and severe scarring that restricts natural movement are not uncommon consequences of traumatic accidents or surgeries that require a large amount of tissue removal," he said. "We must find more ways to help individuals who are struggling with the aftermath of these potentially devastating problems."


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    • Contact: Anita Srikameswaran
    SrikamAV@upmc.edu
    412-578-9193
    University of Pittsburgh Schools of the Health Sciences
    Source:Eurekalert

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