Navigation Links
Pioneers in Alzheimer's research: Research couple honored for its lifetime achievement
Date:7/16/2013

opped, the synapses regenerate and the mice recover from amnesia. This observation shows that the disease process is in principle reversible.

Eckhard Mandelkow: "I am of the opinion that an effective therapy against Alzheimer is possible. Crucial, in my view, is that the treatment is started early enough. Many of today's therapy approaches might have failed on account of the fact that they are applied too late. Since a disease is usually only diagnosed when typical symptoms such as memory dysfunctions are evident. At this time, the brain is however already severely damaged."

Recently, the couple has examined 200,000 substances, in order to find an active agent against the aggregation of tau. Some of these substances were found to be potential candidates for drugs. Their effect will now be further explored.

Prof. Dr. Eckhard Mandelkow studied physics and did his PhD at the Max Planck Institute for Medical Research in Heidelberg on the structure of virus proteins. In a subsequent research period at the Brandeis University (USA), he already dealt with proteins of the cytoskeleton and then continued this line of research. Then he focused on the structure and function of proteins of the nerve cells, especially of motor proteins, tau proteins and their pathological changes during the neurodegeneration. He is the head of the working group "Structural principles of neurodegeneration" at the DZNE/caesar in Bonn.

Dr. Eva-Maria Mandelkow studied medicine, worked for several years in the clinic and then pursued a career in fundamental research. She received her PhD at the Max Planck Institute for Medical Research in Heidelberg for her work in muscle physiology. This was followed by research periods at the Brandeis University (USA), the Scripps Research Institute (USA) and at the MRC Laboratory in Cambridge (UK), where she dealt with proteins of the cytoskeleton. Eva-Maria Mandelkow heads the working group "Cell and animal models of neurodegen
'/>"/>

Contact: Dirk Förger
presse@dzne.de
49-228-433-02260
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. MIT research: The power of being heard
2. UC research: Tracking Lake Erie water snake in fight against invasive fish
3. MIT research: Study finds room to store CO2 underground
4. UC research: Saving habitat key to songbirds survival
5. Research: Modern Portfolio Theory optimizes conservation practices
6. Research: Many programs to help diabetics manage their health do work
7. New research: Soluble corn fiber plays important role in gut health and calcium absorption
8. Influenza research: Can dynamic mapping reveal clues about seasonality?
9. Dartmouth research: The clocks are ticking and the climate is changing
10. PTSD research: Distinct gene activity patterns from childhood abuse
11. New Research: Modified Citrus Pectin - A Potent Anti-Cancer Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/16/2014)... forgotten in museum collections two new species of yellow-shouldered bats have ... and The Field Museum of Natural History and described in the ... additions to the genus Sturnira are part of a ... world, the third one still waiting to be officially announced. , ...
(Date:4/16/2014)... top of a leaf looks like one seamless surface; ... up of a patchwork of cells in a variety ... individually take on their own unique forms, Caltech biologist ... to pinpoint the shape-controlling factors in pavement cells, which ...
(Date:4/16/2014)... Armand-Frappier has just received a research grant from the National ... The 5-year grant is to pursue cutting-edge research in the ... biomedical potential in the field of oncology as well as ... at this level is an accomplishment in itself," said Yves ...
Breaking Biology News(10 mins):Two new species of yellow-shouldered bats endemic to the Neotropics 2For cells, internal stress leads to unique shapes 2High-level NIH grant goes to professor Nicolas Doucet of INRS 2
... Whitehead Institute scientists report that the gene mutated ... syndrome also prevents activation of mTORC1, a critical nutrient-sensing ... is an unexpected finding, as some cancers keep this ... expansion. In the case of Birt-Hogg-Dub syndrome, the mutated ...
... of ZooKeys - no. 346 ... on its day of publication last Friday. This marks ... taxonomic names for animals. The innovative workflow was jointly ... and a U.S. National Science Foundation project to ...
... The Prime Minister of Malaysia today outlined his country,s ... development goals, saying they need to address the relief ... concerns. Prime Minister Najib Razak commended the Millennium ... eight objectives agreed by nations in 2000 for completion ...
Cached Biology News:Gene responsible for hereditary cancer syndrome found to disrupt critical growth-regulating pathway 2Next-generation global e-infrastructure for taxon names registry 2As world sets new development goals, Malaysia calls for poverty relief within green agenda 2As world sets new development goals, Malaysia calls for poverty relief within green agenda 3As world sets new development goals, Malaysia calls for poverty relief within green agenda 4
(Date:1/14/2014)... 2014 Carahsoft and CDS Federal Services ... 2014 at 2pm EST (11am PST), “Natural Language Processing: ... on how technology can turn raw, heterogeneous data into ... agencies. The online webinar will last approximately one hour. ...
(Date:1/14/2014)... 2014 The largest international professional organization of ... therapeutic derivatives thereof has endorsed an educational program ... the challenges of adulterated herb and botanical products. ... The Society for Medicinal Plant and Natural ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Global ... developing innovative information technology solutions for patients, physicians, ... care stakeholders, announced today the signing of a ... Food and Drug Administration (FDA). This initiative ...
(Date:1/14/2014)... CA (PRWEB) January 14, 2014 Independent ... County), California, and Montreal, Canada, has big ideas for ... non-fiction. The press's goals are to produce high-quality, low-cost, ... to support local businesses. , The first major ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2Bitingduck Press Looks Forward to 2014 With Multimedia E-books 2
... Tengion Neo-Bladder(TM) Franchise , , ... Inc. , a clinical stage regenerative medicine company focused ... that it has completed a second closing of its ... million in additional equity capital from the company,s existing ...
... 19 Kornberg Associates Architects,( http://www.kornberg.com ) has opened ... the Okinawa Institute for Science and Technology (OIST) to ... graduate,university. Ken Kornberg, president and founder, made the announcement. ... presence in Japan opens up many doors for us ...
... Nov. 18 Tissue Genesis, Inc., an innovator ... announced that,effective immediately, the Tissue Genesis Cell Isolation ... The Tissue ... system that,recovers potentially regenerative cells from a patient,s ...
Cached Biology Technology:Tengion Announces Second Closing of Series C Financing 2Tengion Announces Second Closing of Series C Financing 3Kornberg Associates Architects Opens Tokyo Office 2Tissue Genesis Applies CE Mark to Its Adult Stem Cell Isolation System 2Tissue Genesis Applies CE Mark to Its Adult Stem Cell Isolation System 3Tissue Genesis Applies CE Mark to Its Adult Stem Cell Isolation System 4Tissue Genesis Applies CE Mark to Its Adult Stem Cell Isolation System 5
Application: for RNase- decontamination , Registered Trademark of Ambion. ,Special grade: for molecular biology Density: 1.00 g/mL (20 C) Suitab tst: RNase decontamination in accordance...
... the needs of the biopharmaceutical ... supports fast cell growth rates ... maintaining high cell viability and ... the Baculovirus Expression Vector System ...
A set of five proteins which can be used to calibrate a Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) or Electrospray Ionization (ESI) mass spectrometer....
... Duet™ Trx•Tag™ Ek Adaptor encodes a T7 ... site (rbs), ATG translation initation codon, and ... is a 109 aa sequence that encodes ... demonstrated to enhance solubility of many proteins ...
Biology Products: