Navigation Links
Pig brain models provide insights into human cognitive development
Date:3/14/2013

URBANA A mutual curiosity about patterns of growth and development in pig brains has brought two University of Illinois research groups together. Animal scientists Rod Johnson and Ryan Dilger have developed a model of the pig brain that they plan to use to answer important questions about human brain development.

"It is important to characterize the normal brain growth trajectory from the neonatal period to sexual maturity," said Johnson.

"Until we know how the brain grows, we don't know what is going to change," added Dilger.

In cooperation with the Beckman Institute, they performed MRI scans on the brains of 16 piglets, starting at the age of 2 weeks, then at 4 weeks, and then at 4-week intervals up to 24 weeks.

"We have world-class people at the Beckman Institute who are pushing and developing the next generation of neuroimaging technology, so we're able to connect with them and take advantage of their expertise," said Johnson.

Matt Conrad, a student in Johnson's lab, used three-dimensional visualization software on over 200 images to manually segment each region on three planes. The software put the information together into a three-dimensional image of the pig brain. This is used to determine the volume of the different structures.

When the piglets were at Beckman for their imaging sessions, Dilger performed other tests, including diffusion tensor imaging (DTI), which shows how neural tracks develop, allowing the exploration of brain complexity and of how neurons form. It was also possible to measure neurochemicals, including creatine and acetylcholine, in the brain, which provides a unique insight into brain metabolism.

The end result of this work is what they call the deformable pig brain atlas.

"We are taking 16 pigs and averaging them, so it's more representative of all pigs," said Dilger. "You can then apply it to any individual pig to see how it's different."

"It's cal
'/>"/>

Contact: Susan Jongeneel
sjongene@illinois.edu
217-333-3291
University of Illinois College of Agricultural, Consumer and Environmental Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. REST is crucial for the timing of brain development
2. Holding a mirror to brain changes in autism
3. Strong scientific evidence that eating berries benefits the brain
4. The Japanese traditional therapy, honokiol, blocks key protein in inflammatory brain damage
5. Step forward in research into new treatments for brain edema
6. University of Alberta led research may have discovered how memories are encoded in our brains
7. Nanotherapy: Treating deadly brain tumors by delivering big radiation with tiny tools
8. Friendly to a fault, yet tense: Personality traits traced in brain
9. New discoveries about brain-hand connection sought to improve therapies, treatments, prosthetics
10. Autism risk gene linked to differences in brain structure
11. Amyloid beta in the brain of individuals with Alzheimers disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/12/2015)... WINSTON-SALEM, N.C. , March 12, 2015 ... afternoon at Brenner Children,s Hospital, part of Wake Forest ... an outreach initiative for the 2015 ACC Men,s Basketball ... taking pictures with them and getting their autographs. ... Wake Forest Baptist. It is the only children,s hospital ...
(Date:3/11/2015)... March 11, 2015   The Sync Project™ ... to scientifically measure and harness music to improve ... biometrics and objective measurements of physiology, enabling the ... scale in large populations. It is designed for ... clinicians perform rigorous studies and accelerate the discovery ...
(Date:3/10/2015)... OXFORD, Conn. , March 10, 2015 /PRNewswire/ ... NXTDW) ("NXT-ID" or the "Company"), a biometric authentication ... reports the company,s Wocket™ smart wallet has been ... 2015" by Rethink Modern. Rethink Modern ... sharing modern and innovative items for your home and lifestyle that ...
Breaking Biology News(10 mins):Introducing The Sync Project, a Global Collaboration Harnessing the Scientific Potential of Music for Health 2Introducing The Sync Project, a Global Collaboration Harnessing the Scientific Potential of Music for Health 3NXT-ID's Wocket Smart Wallet Named Number One Best Tech Gift for 2015 by Rethink Modern 2NXT-ID's Wocket Smart Wallet Named Number One Best Tech Gift for 2015 by Rethink Modern 3NXT-ID's Wocket Smart Wallet Named Number One Best Tech Gift for 2015 by Rethink Modern 4
... University of Illinois at Chicago College of Medicine have discovered ... to create the devastation of Huntington,s disease. The report of ... The researchers were able to show that the mutated ... expressed only in neurons and, further, to show what effect ...
... There won,t be anymore waiting in the dark at this ... by a group of engineering researchers at McMaster University has ... The researchers are also hoping that the prototype ... The bus shelter is located on the west side of ...
... out as individuals and leave telltale signs of our ... are fingerprints really for? According to Roland Ennos, from ... have fingerprints and some South American monkeys have ridged ... fingerprints are there to help us hang onto objects ...
Cached Biology News:Huntington's disease deciphered 2Huntington's disease deciphered 3Flexible solar strips light up campus bus shelter 2Urban myth disproved: Fingerprints do not improve grip friction 2
(Date:3/26/2015)... CA (PRWEB) March 26, 2015 PRC ... (CRO), announced today several management and executive appointments effective ... Chief Financial Officer (CFO) and member of the Board ... of Business Operations, and Sue Dowden will assume the ... co-founder and current Chief Operations Officer (COO), has been ...
(Date:3/26/2015)...  BioNano Genomics, Inc., the leader in genome mapping, ... chief commercial officer. Salyer has more than 20 years ... life sciences. At BioNano, Salyer will oversee the commercialization ... to assemble a comprehensive view of complex genomes to ... institutions located in the United States ...
(Date:3/26/2015)... 26, 2015 PAREXEL International Corporation ... clinical research organization , announced today that ... to acquire all of the business assets of ... provider of specialized pharmacovigilance services, based in ... detection, assessment, monitoring, and prevention of adverse ...
(Date:3/26/2015)... Ale Gicqueau, Founder and President of ... Affairs at Align Technology, on “ Conducting Postmarket Registries ... 2015 Global Conference and Exhibition on April 25th through ... During the poster presentation, Ale Gicqueau and Victor Chen ... Postmarket Registry, the requirements and resources to conduct the ...
Breaking Biology Technology:PRC Clinical Announces Key Management Appointments and Launches East Coast Operations 2PRC Clinical Announces Key Management Appointments and Launches East Coast Operations 3BioNano Genomics Appoints Terry Salyer as Chief Commercial Officer 2BioNano Genomics Appoints Terry Salyer as Chief Commercial Officer 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 2Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 3
... 14 Neurocrine Biosciences,Inc. (Nasdaq: NBIX ) announced ... been appointed President and Chief Executive,Officer and a member ... will step down as President and Chief Executive Officer ... of the Board of,Directors., "While this was a ...
... Industry Ltd. (Nasdaq: SHMR ) ("Shamir"), a ... progressive ophthalmic lens,market, announced today that its board ... aggregate amount of US$ 4.0 million (approximately NIS,15.1 ... rate of,exchange), or approximately US$ 0.243 (approximately NIS ...
... ... Meet Growing Global Demand, WILMINGTON, Del., Jan. ... Fanandakis group vice president - DuPont Applied,BioSciences. In this newly ... a range of bio-based,products and technologies to meet growing global ...
Cached Biology Technology:Neurocrine Announces Appointment of Kevin Gorman, Ph.D., as President and Chief Executive Officer 2Shamir Optical Industry Ltd. Announces Declaration of a Cash Dividend 2Shamir Optical Industry Ltd. Announces Declaration of a Cash Dividend 3DuPont Names Nicholas Fanandakis as Group Vice President - DuPont Applied BioSciences 2
... Fully automated microarray slide processing offering ... The trend to miniaturization, automation and ... a powerful tool with many applications ... These applications range from gene expression ...
... Thermomixer R offers maximum application versatility ... heating, and cooling. Its active heating/cooling ... and temperature control ranges. Five different ... micro test tubes, are available for: ...
... Protein DetectorTM Microarray Dot Blot Kits ... accuracy and quantitation over a wide range ... formats ) detection. They are ideal ... profiling hundreds of samples for the presence ...
... is a high quality microarray scanner based on ... rejection and spatial resolution. The DNAscope LM ... cost microarray scanner that is upgradeable to a ... Features: Includes control module (computer), ...
Biology Products: