Navigation Links
Physical health scores predict breast cancer outcomes
Date:4/6/2011

ORLANDO, Fla. Breast cancer survivors with poor physical health scores had an elevated risk of poorer cancer outcomes, including recurrence and death, according to the results of an observational study presented at the AACR 102nd Annual Meeting 2011, held April 2-6.

Survivors of breast cancer who had poor health scores were 27 percent more likely to experience either a recurrence of their cancer or a new breast cancer. Physical health also impacted survival quite strongly; risk of death from any cause was 65 percent greater among those with poorer health scores.

Researchers from UC San Diego Moores Cancer Center used data from three of the four cohorts included in the After Breast Cancer (ABC) Pooling Project to analyze the association of poor physical health and survival, along with a cluster of comorbidities. The physical health score has been shown in smaller studies to be an important predictor of future breast cancer events and overall survival in women with breast cancer.

"Here we see a single metric that predicts risk," said John P. Pierce, Ph.D., who is the Sam M. Walton professor for cancer prevention and associate director for population sciences at Moores Cancer Center. "Variables cluster together and are summarized in the physical health score. The question becomes how to improve the physical health status of this particular group of breast cancer survivors."

Physical health scores were measured for a total of 9,387 early-stage breast cancer survivors, using the SF-36 a multipurpose, short-form health survey taken after diagnosis, with follow-up occurring on average seven years later. The physical health score includes information about how an individual perceives their own physical functioning, bodily pain and limitations caused by physical problems.

About half the women in the sample had a physical health score that met the survey definition of poor physical health. Low physical health scores were strongly associated with a higher body mass index. The women with low scores were less physically active and were 64 percent more likely to have sleep difficulties. They also had 50 percent higher rates of high blood pressure and diabetes and were twice as likely to have arthritis.

By addressing this cluster of health concerns, clinicians can help women improve their health, feel better about their lives and reduce associated breast cancer risks, according to Pierce.

"Instead of looking at breast cancer survivors as a whole, we need to focus on the women with low physical health scores, those most at risk," he said. "An increase of 5 percent in their physical health score can reduce their risk. We can empower them to take charge of their health and thereby improve their chance of survival as well as their quality of life."


'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Related biology news :

1. Biophysical Society announces 2011 Student Research Achievement award winners
2. American Physical Society online journals available free in US high schools
3. Upcoming conference: Biophysical Societys 55th Annual Meeting
4. Biophysical Society announces winners of 2011 Student Travel Awards
5. Biophysical Society announces winners of 2011 CPOW Travel Awards
6. Biophysical Society announces winners of 2011 International Travel Awards
7. Biophysical Society announces winners of 2011 Minority Travel Awards
8. Using chaos to model geophysical phenomena
9. Psychologists identify influence of social interaction on sensitivity to physical pain
10. Wearable sensor technology to measure physical activity
11. Biophysical Society announces 2011 society fellows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... , April 11, 2017 No ... but researchers at the New York University Tandon ... of Engineering have found that partial similarities between ... systems used in mobile phones and other electronic ... The vulnerability lies in the fact ...
(Date:4/5/2017)... -- The Allen Institute for Cell Science today announces the ... and dynamic digital window into the human cell. The ... of deep learning to create predictive models of cell ... growing suite of powerful tools. The Allen Cell Explorer ... available resources created and shared by the Allen Institute ...
(Date:4/4/2017)... YORK , April 4, 2017   EyeLock ... today announced that the United States Patent and Trademark ... patent broadly covers the linking of an iris image ... same transaction) and represents the company,s 45 th ... latest patent is very timely given the multi-modal biometric ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... The Blavatnik ... Winners and six Finalists of the 2017 Blavatnik Regional Awards for Young Scientists. ... Foundation and administered by the New York Academy of Sciences to honor the ...
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, ... and biotechnology industries to improve patient outcomes and quality of life, will now ... testing are being attributed to new regulatory requirements for all new drug products, ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... Personal eye wash is a basic first ... eye at a time. So which eye do you rinse first if a dangerous substance ... Plum Duo Eye Wash with its unique dual eye piece. , “Whether its ...
(Date:10/11/2017)... LAGUNA HILLS, Calif. , Oct. 11, 2017 /PRNewswire/ ... London (ICR) and University of ... tool to risk-stratify patients with multiple myeloma (MM), in a ... . The University of Leeds is ... Myeloma UK, and ICR will perform the testing services to ...
Breaking Biology Technology: