Navigation Links
Physical health scores predict breast cancer outcomes
Date:4/6/2011

ORLANDO, Fla. Breast cancer survivors with poor physical health scores had an elevated risk of poorer cancer outcomes, including recurrence and death, according to the results of an observational study presented at the AACR 102nd Annual Meeting 2011, held April 2-6.

Survivors of breast cancer who had poor health scores were 27 percent more likely to experience either a recurrence of their cancer or a new breast cancer. Physical health also impacted survival quite strongly; risk of death from any cause was 65 percent greater among those with poorer health scores.

Researchers from UC San Diego Moores Cancer Center used data from three of the four cohorts included in the After Breast Cancer (ABC) Pooling Project to analyze the association of poor physical health and survival, along with a cluster of comorbidities. The physical health score has been shown in smaller studies to be an important predictor of future breast cancer events and overall survival in women with breast cancer.

"Here we see a single metric that predicts risk," said John P. Pierce, Ph.D., who is the Sam M. Walton professor for cancer prevention and associate director for population sciences at Moores Cancer Center. "Variables cluster together and are summarized in the physical health score. The question becomes how to improve the physical health status of this particular group of breast cancer survivors."

Physical health scores were measured for a total of 9,387 early-stage breast cancer survivors, using the SF-36 a multipurpose, short-form health survey taken after diagnosis, with follow-up occurring on average seven years later. The physical health score includes information about how an individual perceives their own physical functioning, bodily pain and limitations caused by physical problems.

About half the women in the sample had a physical health score that met the survey definition of poor physical health. Low physical health scores were strongly associated with a higher body mass index. The women with low scores were less physically active and were 64 percent more likely to have sleep difficulties. They also had 50 percent higher rates of high blood pressure and diabetes and were twice as likely to have arthritis.

By addressing this cluster of health concerns, clinicians can help women improve their health, feel better about their lives and reduce associated breast cancer risks, according to Pierce.

"Instead of looking at breast cancer survivors as a whole, we need to focus on the women with low physical health scores, those most at risk," he said. "An increase of 5 percent in their physical health score can reduce their risk. We can empower them to take charge of their health and thereby improve their chance of survival as well as their quality of life."


'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Related biology news :

1. Biophysical Society announces 2011 Student Research Achievement award winners
2. American Physical Society online journals available free in US high schools
3. Upcoming conference: Biophysical Societys 55th Annual Meeting
4. Biophysical Society announces winners of 2011 Student Travel Awards
5. Biophysical Society announces winners of 2011 CPOW Travel Awards
6. Biophysical Society announces winners of 2011 International Travel Awards
7. Biophysical Society announces winners of 2011 Minority Travel Awards
8. Using chaos to model geophysical phenomena
9. Psychologists identify influence of social interaction on sensitivity to physical pain
10. Wearable sensor technology to measure physical activity
11. Biophysical Society announces 2011 society fellows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... Research and Markets has announced the addition of the ... The report forecasts the biometrics ... a CAGR of 12.28% during the period 2016-2020. ... with inputs from industry experts. The report covers the market landscape ... includes a discussion of the key vendors operating in this market. ...
(Date:6/22/2016)... 2016  The American College of Medical Genetics and Genomics ... as one of the fastest-growing trade shows during the ... Bellagio in Las Vegas . ... growth in each of the following categories: net square feet ... of attendees. The 2015 ACMG Annual Meeting was ranked 23 ...
(Date:6/22/2016)... ANGELES , June 22, 2016 /PRNewswire/ ... identity management and verification solutions, has partnered ... edge software solutions for Visitor Management, Self-Service ... provides products that add functional enhancements ... partnership provides corporations and venues with an ...
Breaking Biology News(10 mins):
(Date:6/23/2016)...   EpiBiome , a precision microbiome engineering company, ... financing from Silicon Valley Bank (SVB). The financing will ... its drug development efforts, as well as purchase additional ... has been an incredible strategic partner to us – ... would provide," said Dr. Aeron Tynes Hammack , ...
(Date:6/23/2016)... LOUISVILLE, Ky. , June 23, 2016 /PRNewswire/ ... from two Phase 1 clinical trials of its ... double-blind, placebo-controlled, single and multiple ascending dose studies ... and pharmacodynamics (PD) of subcutaneous injection in healthy ... APL-2 subcutaneously (SC) either as a single dose ...
(Date:6/23/2016)... Francisco, CA (PRWEB) , ... June 23, 2016 ... ... (EDC) software, is exhibiting at the Pennsylvania Convention Center and will showcase its ... Annual conference. ClinCapture will also be presenting a scientific poster on Disrupting Clinical ...
(Date:6/23/2016)... PUNE, India , June 23, 2016 /PRNewswire/ ... culture media market research report to its pharmaceuticals ... company profiles, product details and much more. ... market spread across 151 pages, profiling 15 companies ... now available at http://www.reportsnreports.com/reports/601420-global-cell-culture-media-industry-2016-market-research-report.html . ...
Breaking Biology Technology: