Navigation Links
'Petri dish lens' gives hope for new eye treatments
Date:1/31/2013

A cure for congenital sight impairment caused by lens damage is closer following research by scientists at Monash University.

Associate Professor Tiziano Barberi and Dr Isabella Mengarelli from the Australian Regenerative Medicine Institute at Monash University are closer to growing parts of the human eye in the lab. They have, for the first time, derived and purified lens epithelium - the embryonic tissue from which the lens of the eye develops. The purity of the cells paves the way for future applications in regenerative medicine.

Further, the researchers caused these precursor cells to differentiate further into lens cells, providing a platform to test new drugs on human tissue in the lab.

Pluripotent stem cells have the ability to become any cell in the human body including, skin, blood and brain matter. Once the stem cells have begun to differentiate, the challenge for researchers is to control the process and produce only the desired, specific cells.

Using a technology known as fluorescence activated cell sorting (FACS), Associate Professor Barberi and his team were able to identify the precise combination of protein markers expressed in the lens epithelium that enabled them to isolate those cells from the rest of the cultures. Most markers are common to more than one type of cell, making it challenging to determine the exact mix of markers unique to the desired cells.

Associate Professor Barberi said this breakthrough would eventually help cure visual impairment caused by congenital cataracts or severe damage to the lens from injury through lens transplants.

"The lens has, to some extent, the ability to heal well following surgical intervention. However, with congenital cataracts, the fault is wired into the DNA, so the lens will re-grow with the original impairment. This problem is particularly prevalent in developing countries," he said.

Combined with advances in producing pluripotent stem
'/>"/>

Contact: Emily Walker
emily.walker@monash.edu
61-399-034-844
Monash University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Persistence or extinction: Through a mathematical lens
2. Cost-effective production of infrared lenses
3. Self-assembling nanocubes for next generation antennas and lenses
4. Oscillating gel gives synthetic materials the ability to speak
5. Location, location, location: Membrane residence gives proteases novel abilities
6. New ancient shark species gives insight into origin of great white
7. New brain gene gives us edge over apes, study suggests
8. New model gives hands-on help for learning the secrets of molecules
9. Exome sequencing gives cheaper, faster diagnosis in heterogeneous disease
10. Esther B. OKeeffe Foundation gives $2 million to the Scripps Research Institute
11. Analysis of speed of Greenland glaciers gives new insight for rising sea level
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... 2014   Neurotechnology , a provider of ... of the VeriLook Surveillance 3.0 software development ... biometric face identification using live video streams from ... new version not only identifies faces in a ... while they are moving through the video frame. ...
(Date:10/14/2014)... Cancer Research shows SIRT6—a protein known to inhibit ... development of skin cancers by turning on an enzyme ... cells. , Previously considered protective, SIRT6 is part of ... regulate genomic stability and prevent some of the genetic ... which can lead to cancer. This study, in the ...
(Date:10/14/2014)... N.Y. – Scientists have sequenced the house fly genome ... one might expect from an insect that thrives in ... published Oct. 14 in the journal Genome Biology ... biology and of how flies quickly adapt to resist ... Adult house flies (Musca domestica) carry and transmit more ...
Breaking Biology News(10 mins):VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2House fly genome reveals expanded immune system 2
... the bioinformatics expert who developed the Barcode of Life ... community, has won this year,s Ebbe Nielsen Prize from ... Informatics Director for the Biodiversity Institute of Ontario at ... Barcode of Life (iBOL) project. He is the first ...
... of discarded materials inside upright pipes can purify dirty ... growing vegetables and flushing toilets, according to Penn State ... depleting," said Robert D. Cameron, doctoral student in horticulture. ... at alternatives on how we can take wastewater and ...
... The bioactive compounds of cereals are concentrated in ... most of them have a low bio-accessibility. In ... tools for process monitoring were developed that support ... grain debranning, fine grinding and classification of grain ...
Cached Biology News:Roots meshed in waste materials could clean dirty water 2Creating new healthy ingredients by innovative milling techniques and processes for cereal grains 2Creating new healthy ingredients by innovative milling techniques and processes for cereal grains 3
(Date:10/18/2014)... 2014 The Asia-Pacific hardware encryption display ... Asia-Pacific with analysis and forecast of revenue. This market ... to reach $51,362.6 million by 2018, at a CAGR ... the TOC of the Asia-Pacific hardware encryption market report, ... This also provides a glimpse of the segmentation of ...
(Date:10/18/2014)... York, NY (PRWEB) October 18, 2014 ... a healthy rate in the five years to 2014. ... several federal renewable energy tax credits that encouraged the ... have enacted renewable portfolio standards (RPSs), which require local ... percentage of their total energy portfolio. Increased campaigning for ...
(Date:10/18/2014)... (PRWEB) October 18, 2014 The ... Stress, Holter Monitor), by End-user (Hospitals, Home/Ambulatory, Research ... (Single, 3-6, 12) -Global Forecast to 2020” provides ... challenges, opportunities, current market trends, and strategies impacting ... estimates and forecasts of the revenue and share ...
(Date:10/17/2014)... Germany , October 17, 2014 ... Translational research in cancer and other diseases will ... American Society of Human Genetics annual meeting   ... to Ingenuity ®  Knowledge Base greatly exceeds any ... Ingenuity ®  Variant Analysis™ adds fully integrated ...
Breaking Biology Technology:The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 3Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 2Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 3The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 2The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 3The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 4The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 2QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 3QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 6
... Feb. 4 GeoVax Labs, Inc.,(OTC Bulletin Board: GOVX), ... diseases caused by,HIV-1 (Human Immunodeficiency Virus) and other infectious ... CEO & Investor Conference,2009 will be webcast live by ... Hotel in New York City on February 9 and ...
... (Pink Sheets: MNCN), Mach One Corporation, a global health ... long term benefit to the agricultural and consumer markets, ... to acquire Ceres Organic Harvest, Inc. an organic grain ... feed and dairy industries.Under the terms of the agreement, ...
... first free website allowing patients to upload and share diagnostic-quality ... , ... Durham, NC (PRWEB) February 4, ... world,s first free website allowing patients to upload and share ...
Cached Biology Technology:GeoVax to Webcast Its Presentation at the BIO CEO & Investor 2009 Conference 2GeoVax to Webcast Its Presentation at the BIO CEO & Investor 2009 Conference 3Mach One Corporation Signs Definitive Agreement to Acquire Ceres Organic Harvest, Inc. 2World's First Website for Patients to Share Diagnostic-Quality Medical Images 2
... Species Tissue Array (MSTA) slides were designed to ... tissues from multiple species. Tissue slices from ... slide which can then be treated as a ... in situ hybridization. This format ...
... yellow solution. In PBS ... and other proprietary stabilizers; ... formulated to stabilize activity ... conjugates at high conjugate ...
... cells-directed transfection reagent : jetPEI-RGD ... which allows targeted efficient transfection ... cells. Integrins are adhesion molecules ... adhesion processes. Many integrins, including ...
...
Biology Products: