Navigation Links
Perception of fertility affects quality of life in young, female cancer survivors
Date:8/12/2013

A new study led by a University of Colorado Cancer Center member recently published in the journal Quality of Life Research reveals that in young, female cancer survivors, quality of life is significantly impaired long after treatment. The study compared 59 cancer survivors to 66 healthy controls and found that, as expected, cancer survivors showed higher stress and anxiety than the general population. Of note, survivors reported particular stress around the issues of sexual problems, physical pain and fatigue. The study also measured hormone levels reflecting woman's number of eggs, and showed that among young, female cancer survivors, those with reassuring fertility status were likely to report higher quality of life once treatment ends.

"What it came down to was a woman's opinion of her own fertility status after cancer treatment," says Laxmi Kondapalli, MD, MSCE, director of the CU Cancer Center Oncofertility Program.

See, there was one intervening step between normal ovarian reserve and quality of life: the regularity of a woman's menstrual cycle after undergoing chemotherapy and/or radiation treatment for cancer. All women lose a certain number of eggs during these treatments, but those with higher baseline reserve are more likely to withstand the treatment with their overall fertility unaffected. Women with lower ovarian reserve at baseline are more likely to have impaired fertility after treatment.

"But it wasn't the lab and ultrasound markers of ovarian reserve alone that affected quality of life," Kondapalli says. "It was a woman's opinion of her fertility status based on her menstrual cycle that had the most impact on quality of life."

Following cancer treatment, many women think that if they maintain regular menstrual cycles, their fertility is preserved, and that if their menstrual cycles become irregular, then they are likely infertile due to treatment.

"This isn't necessarily the case, because we are finding that menstrual cyclicity is a poor predictor of fertility status in these young, female cancer survivors," Kondapalli says. "Survivors may be falsely reassured if they resume normal periods, or they may be unnecessarily stressed if they don't get regular periods after cancer treatment."

According to Kondapalli, women with high ovarian reserve are less likely to experience symptoms of early menopause after cancer treatment. And it is these symptoms that go on to influence young patients' quality of life.

"I think what our study demonstrates is that clearly there are many components that impact a survivor's quality of life after cancer treatment. Although objective markers of ovarian reserve play an important role, a woman's perception of her own fertility status was more influential in her overall quality of life," Kondapalli says.

Understanding the factors that influence quality of life in this population may help identify ways to manage late effects of treatment and improve comprehensive survivorship care.


'/>"/>

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver
Source:Eurekalert

Related biology news :

1. Another scientific proof of the difference in social perception between men and women
2. Monell scientists help identify a missing link in taste perception
3. New research questions how fat influences flavor perception
4. Humidity increases odor perception in terrestrial hermit crabs
5. Misperception of weight is an important barrier to weight loss
6. Perception and preference may have genetic link to obesity
7. Clue, a Berlin Startup Founded By a Woman, Launches An Intelligent Tracking App That Decodes a Womans Fertility Cycle
8. Important fertility mechanism discovered
9. Fertility needs in high-yielding corn production
10. NSF grant boosts research on proteins that affect fertility
11. New chemo drug gentler on fertility, tougher on cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... Ampronix facilitates superior patient care by providing unparalleled technology to leaders of the medical ... premium product recently added to the range of products distributed by Ampronix. ... ... ... Ampronix News ...
(Date:5/12/2016)... , May 12, 2016 WearablesResearch.com , ... published the overview results from the Q1 wave of ... recent wave was consumers, receptivity to a program where ... with a health insurance company. "We were ... share," says Michael LaColla , CEO of Troubadour ...
(Date:4/28/2016)... and BANGALORE, India , April 28, ... Systems, a product subsidiary of Infosys (NYSE: INFY ... announced a global partnership that will provide end ... use mobile banking and payment services.      (Logo: ... key innovation area for financial services, but it also plays ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... BEACH, Calif. , June 23, 2016  Blueprint ... new biological discoveries to the medical community, has closed ... co-founder Matthew Nunez . "We have ... us with the capital we need to meet our ... will essentially provide us the runway to complete validation ...
(Date:6/23/2016)... Francisco, CA (PRWEB) , ... June 23, 2016 ... ... (EDC) software, is exhibiting at the Pennsylvania Convention Center and will showcase its ... Annual conference. ClinCapture will also be presenting a scientific poster on Disrupting Clinical ...
(Date:6/23/2016)... , June 22, 2016  Amgen (NASDAQ: ... of the QB3@953 life sciences incubator to ... health. The shared laboratory space at QB3@953 was created ... a key obstacle for many early stage organizations - ... of the sponsorship, Amgen launched two "Amgen Golden Ticket" ...
(Date:6/22/2016)... DUBLIN , June 22, 2016 Research ... and Global Markets" report to their offering. ... $39.4 billion in 2014 from $29.3 billion in 2013. The market ... (CAGR) of 13.8% from 2015 to 2020, increasing from $50.6 billion ... and projected product forecasts during the forecast period (2015 to 2020) ...
Breaking Biology Technology: