Navigation Links
Penn researchers identify immune cells that fight parasites may promote allergies and asthma
Date:3/11/2010

thma and allergy.

The National Institutes of Health estimates that as many as 40 to 50 million Americans suffer from allergic diseases. Consistent with this theory of redundancy, there are reports that show equatorial regions with an abundance of helminth parasites have populations that encounter lower rates of asthma and allergies.

"From an evolutionary perspective, it is likely that we evolved a complex immune response to fight parasitic worms, but our more sanitized environment no longer has this same population of parasites," Artis said. "This newly identified cell population could represent one of the earliest events in this type of immune response, which offers potential new targets for treatment of infection and allergic inflammation."

The research team demonstrated that a molecule called IL25, a member of the IL17 cytokine family, promotes the accumulation of a lineage-negative multipotent progenitor cell population in the intestine that promotes T cell responses associated with asthma and helminth infection. The resulting cell population gives rise to cells of macrophage and granulocyte lineages. The ability of IL25 to induce the emergence of an MPP cell population identifies a link between the IL17 cytokine family and extramedullary haematopoiesis and suggests a previously unrecognized innate immune pathway that promotes TH2 cytokine responses at mucosal sites.


'/>"/>

Contact: Jordan Reese
jreese@upenn.edu
215-573-6604
University of Pennsylvania
Source:Eurekalert

Page: 1 2

Related biology news :

1. VAI researchers develop tool to help study prostate cancer
2. Researchers examine plants ability to identify, block invading bacteria
3. Community involvement important in fight against childhood obesity, according to UTHealth researchers
4. Exercise counters negative effects of weight regain, researchers find
5. Rice researchers make graphene hybrid
6. New dinosaur rears its head; U-M researchers part of team announcing find
7. Discovery in legumes could reduce fertilizer use, aid environment: Stanford researchers
8. Researchers fishing for cancer cure discover active DHA derivatives
9. Researchers determine how ATP, molecule bearing the fuel of life, is broken down in cells
10. NOAA, NASA and Old Dominion researchers measure impacts of changing climate on ocean biology
11. Researchers issue outlook for a significant New England red tide in 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... PAUL, Minn. , Dec. 10, 2014 /PRNewswire/ ... wireless physiologic monitoring, has released a new series ... needs of preclinical toxicology researchers. M series, part ... help toxicologists collect the best possible physiologic data ... Adding functional endpoints to toxicology studies ...
(Date:12/10/2014)... 2014 Research and Markets ( ... "Biometrics Market in Japan 2014-2018" report ... http://photos.prnewswire.com/prnh/20130307/600769 The integration of biometrics ... banking and upgradation of the driver,s license is ... market. Besides the aforementioned projects, biometrics is being ...
(Date:12/3/2014)... , Dec. 2, 2014   Marvin Test ... innovative test solutions for military, aerospace, and manufacturing ... of its successful TS-900 PXI semiconductor test ... features of high-end systems to customers at a ... compared to traditional ATE. "Our ...
Breaking Biology News(10 mins):New telemetry implants expected to change how large animal toxicology studies are conducted 2Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3
... , WHAT: EPA,s top scientist and the ,father of ... our nation,s first preeminent scientist and inventor Benjamin Franklin ... Philadelphia Science Festival. Park visitors and local college ... innovation and invention, and how the current generation can ...
... high-quality assisted reproduction treatment as defined by the European ... ESHRE position paper on Good clinical treatment in Assisted ... patients should be treated the same and with the ... not always the case. The Guide is based ...
... professor in the Virginia Tech Carilion Research Institute and ... and Sciences, has been invited to speak at a ... 11-12 on the security implications of advances in neuroscience. ... four-part policy study on neuroscience and society called Brain ...
Cached Biology News:ESHRE sets standards for cross-border reproductive care 2ESHRE sets standards for cross-border reproductive care 3
(Date:12/19/2014)... (PRWEB) December 19, 2014 Bioject ... developer and manufacturer of needle-free injection technology, today ... with Immunomic Therapeutics, Inc. (“ITI”) for ITI to ... with its LAMP™ vaccine platform. , In ... exclusive Worldwide license to the Biojector®-2000 that triggers ...
(Date:12/19/2014)... BioPlus Specialty Pharmacy (BioPlus), one of ... Nick Maroulis, Pharm.D. to the newly created position of ... this position, Dr. Maroulis will continue to manage the ... our multi-site pharmacies as the company expands. Dr. Maroulis ... time he has served in many different capacities in ...
(Date:12/19/2014)... Calif. , Dec. 19, 2014  Roche (SIX: ... of Bina Technologies, Inc. (Bina), a privately held ... , USA. Bina provides a big data ... generation sequencing (NGS) data. Bina,s proprietary on-market Genomic ... and academic researchers to perform fast and scalable ...
(Date:12/19/2014)... , Dec. 19, 2014 Decision Resources Group ... grow at a 12 percent compound annual growth rate ... the aging population and the increasing adoption of dental ... will also spur demand for dental biomaterials ... implant and periodontal treatments. Other key findings ...
Breaking Biology Technology:Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 2Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 3BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2Roche acquires Bina Technologies and enters the genomic informatics market 2Roche acquires Bina Technologies and enters the genomic informatics market 3Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 3
... , , , , , , Other important parameters for optimizing electroporation. , , ... Field strength , , ... field pulses , Adjustment , ... of DNA/RNA , Influence , ...
... , , Dr. Frank Stahl , ... (Society for Biotechnological Research) , , , , , ... DNA microarrays are a key technology in modern molecular biotechnology. , ... of complex genetic changes, thereby enabling a deeper insight ...
... , , Note: Genomic DNA is fragile. High molecular weight DNA ... tips or equipment when , pipetting genomic DNA. Do not vortex ... Place a 1 cm tail sample into a 1.5 ml microcentrifuge tube; ... To minimize possible cross-contamination, , do not ...
Cached Biology Technology:Optimizing electroporation parameters 2Optimizing electroporation parameters 3Optimizing electroporation parameters 4Optimizing electroporation parameters 5Optimizing electroporation parameters 6An Optimal DNA Microarray Substrate for the Identification of Fetal , and Somatic Liver Stem Cells of the Rat 2An Optimal DNA Microarray Substrate for the Identification of Fetal , and Somatic Liver Stem Cells of the Rat 3An Optimal DNA Microarray Substrate for the Identification of Fetal , and Somatic Liver Stem Cells of the Rat 4An Optimal DNA Microarray Substrate for the Identification of Fetal , and Somatic Liver Stem Cells of the Rat 5An Optimal DNA Microarray Substrate for the Identification of Fetal , and Somatic Liver Stem Cells of the Rat 6Mouse Tail Genomic DNA Isolation Protocol(1) 2
AGAROSE PREP, 50G, 1 EA. Category: Genephor Precast Gels....
in vitro Translation, Accessory Products...
... Origami host strains are K-12 derivatives that ... (trxB) and glutathione reductase (gor) genes, which ... cytoplasm. Studies have shown that expression in ... in another host even though overall expression ...
... Ultrospec 6300 pro UV/Visible Spectrophotometer: ... Pharmacopoeia in terms of instrument specification and ... able to be used for rapid, discrete ... scanning capability., *Press to read high performance ...
Biology Products: