Navigation Links
Penn engineers develop more effective MRI contrast agent for cancer detection
Date:12/23/2011

its environment becomes. This means that the glycol chitosan-coated is a good detector of malignancy, opening up treatment options above and beyond diagnosis.

"You can take any nanoparticle and put this coating on it, so it's not limited to imaging by any means," said Tsourkas. "You could also use it to deliver drugs to tumor sites."

The researchers hope that, within seven to 10 years, glycol-chitosan-coated iron oxide nanoparticles could improve the specificity of diagnostic screening. The ability to accurately detect sites of malignancy by MRI would be an immediate improvement to existing contrast agents for certain breast cancer scans.

"Gadolinium is used as a contrast agent in MRI breast cancer screenings for high-risk patients. These patients are recommended to get an MRI in addition to the usual mammogram, because the sensitivity of mammograms can be poor," said Tsourkas. "The sensitivity of an MRI is much higher, but the specificity is low: the screening detects a lot of tumors, but many of them are benign. Having a tool like ours would allow clinicians to better differentiate the benign and malignant tumors, especially since there has been shown to be a correlation between malignancy and pH."


'/>"/>

Contact: Evan Lerner
elerner@upenn.edu
215-573-6604
University of Pennsylvania
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UC San Diego bioengineers fill holes in science of cellular self-organization
2. Caltech engineers build firast-ever multi-input plug-and-play synthetic RNA device
3. Biomedical engineers detective work reveals antibiotic mechanism
4. Engineers create intelligent molecules that seek-and-destroy diseased cells
5. Iowa student engineers develop hand-held water sanitizer for a thirsty world
6. Ben-Gurion University engineers develop technique to help combat nuclear proliferation
7. LabRoots Launches Social Networking Site for Scientists & Engineers
8. Engineers develop method to disperse chemically modified graphene in organic solvents
9. Case Western Reserve University engineers hit pay dirt with clay mixture
10. New method developed by UC San Diego bioengineers gives regenerative medicine a boost
11. Vanderbilt engineers play key role in new DOE energy frontier research center
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... N.C. , Dec. 10, 2014  That blood pressure ... quite a while. Hypertension – the medical term for high ... the early 1800s, and the inflatable cuff that,s used in ... doesn,t, however, mean there,s nothing new about hypertension, its triggers ... long-held beliefs about the condition and the best ways to ...
(Date:12/10/2014)... 2014  Wake Forest Baptist Medical Center today announced plans ... of Medicine. Funding for this $50 million capital project ... be publicly launched next summer. The ... 60 series R.J. Reynolds Tobacco Company complex, adjacent to ... immediately with plans to be ready to welcome medical ...
(Date:12/5/2014)... , Dec. 4, 2014 Increased ... boosted investments in new testing and inspection technologies. ... given rise to a range of innovative test ... requirements of Generation Y, which is generally more ... a result, product development strategies of test equipment ...
Breaking Biology News(10 mins):Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4
... 8, 2013 How many breakthrough new drugs never ... high risk of liver damage when the drug actually ... international research efforts to modernize tests for drug-induced liver ... & Exposition of the American Chemical Society (ACS), the ...
... , Sept. 6, 2013  Daniel P. Linskey, superintendent-in-chief of the ... Learned from Boston Marathon Bombings" at the 2013 IEEE International ... Linskey,s talk will focus on the aftermath ... response of his department and federal enforcement agencies that ultimately ...
... researchers has discovered the cranium of a fossil ape from ... cranium of the fossil ape Lufengpithecus is significant, ... at Penn State. Jablonski noted that juvenile crania of ... especially those of infants and young juveniles. This cranium is ...
Cached Biology News:Better tests for liver toxicity would mean more medicines -- and safer medicines -- for patients 2Better tests for liver toxicity would mean more medicines -- and safer medicines -- for patients 3Boston Police Chief to Address Boston Marathon Bombings at IEEE Homeland Security Conference in Waltham, Mass., on 12 November 2Researchers discover rare fossil ape cranium in China 2
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... Cingular merger with AT&T? , ,I've read the business stories ... the assets and customers of AT&T Wireless for $41 billion. ... 2 carrier Verizon by 9 million subscribers. The one hitch ... brand and plans to launch a new wireless service under ...
... Many organizations talk a good game about interpersonal skills, influence ... there's a pretty clear chain of command that runs right ... Technology (DoIT) at the University of Wisconsin-Madison, Annie Stunden ... that many more staff with IT responsibilities in other departments ...
... in Carlsbad, California. , Dynal : 400+ employees worldwide, ... in Oslo, Norway. Brown Deer, Wis. ... Dynal Biotech ASA , whose U.S. operations are based ... for $380.4 million. , ,Invitrogen has considered the ...
Cached Biology Technology:Cingular confusion 2Cingular confusion 3Annie Stunden, CIO at the University of Wisconsin-Madison 2Annie Stunden, CIO at the University of Wisconsin-Madison 3Annie Stunden, CIO at the University of Wisconsin-Madison 4Invitrogen to buy Norwegian biotech with operations in Brown Deer 2
...
Whole blood is collected from healthy guinea pigs of either sex from US source which are free of visible diseases at time of blood collection. Hemolytic titer: CH50 = 435 units...
... l-[35S]in vitro cell labeling mix, ... *Aqueous solution stabilized with 0.1% ... pyridine 3,4-dicarboxylic acid. *Amino acid ... labeling containing l-[35S]Methionine and l-[35S]Cysteine. ...
...
Biology Products: