Navigation Links
Penn biologists explain how organisms can tolerate mutations, yet adapt to environmental change
Date:1/20/2010

ons to optimally explore the range of possible phenotypes.

The researchers also used computer simulations to check their result under many alternative versions of the basic model. Although there is not yet sufficient data to test these theoretical results in nature, the authors simulated the evolution of RNA molecules, confirming that their theoretical results could predict the rate of adaptation.

"Biologists have long wondered how can organisms be robust and also adaptable," said Plotkin, assistant professor in the Department of Biology in Penn's School of Arts and Sciences. "After all, robust things don't change, so how can an organism be robust against mutation but also be prepared to adapt when the environment changes? It has always seemed like an enigma."

Robustness is a measure of how genetic mutations affect an organism's phenotype, or the set of physical traits, behaviors and features shaped by evolution. It would seem to be the opposite of evolvability, preventing a population from adapting to environmental change. In a robust individual, mutations are mostly neutral, meaning they have little effect on the phenotype. Since adaptation requires mutations with beneficial phenotypic effects, robust populations seem to be at a disadvantage. The Penn-led research team has demonstrated that this intuition is sometimes wrong.


'/>"/>

Contact: Jordan Reese
jreese@upenn.edu
215-573-6604
University of Pennsylvania
Source:Eurekalert

Page: 1 2

Related biology news :

1. Biologists merge methods, results from different disciplines to find new meaning in old data
2. New handbook for biologists who need more competence or confidence in statistics
3. Biologists discover bacterial defense mechanism against aggressive oxygen
4. Beyond genomics, biologists and engineers decode the next frontier
5. Biologists, educators recognize excellence in evolution education
6. NIMBioS hosts tutorial on optimal control and optimization for biologists
7. Biologists discover death stench is a universal ancient warning signal
8. UTSA plant biologists publish where their peers are -- on the Web
9. Microbiologists find defense molecule that senses respiratory viruses
10. Geobiologists propose that the earliest complex organisms fed by absorbing ocean buffet
11. Biologists rediscover endangered frog population
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... healthy women differ from bacteria in women with ... from Loyola University Chicago Stritch School of Medicine. ... in the American Society for Microbiology,s online journal ... play a role in female urinary health. , ... poorly understood, condition with symptoms similar to urinary ...
(Date:7/9/2014)... the Spanish National Cancer Research Centre (CNIO) have discovered ... also regulates cell division in stratified epitheliathose that form ... the oesophagus or the vaginain adult organisms. According to ... Nature Communications , this factor could also play ... stratified epithelia of the oesophagus and skin. , The ...
(Date:7/9/2014)... Researchers studying critically ill children with traumatic injuries ... patients are likely to develop a hospital-acquired infection. ... Hospital and published online in June in the ... larger efforts that could lead to the clinical ... to prevent or reverse immune system damage following ...
Breaking Biology News(10 mins):CNIO scientists discover that pluripotency factor NANOG is also active in adult organisms 2Immune function predicts infection risk among child trauma patients 2Immune function predicts infection risk among child trauma patients 3
... (January 24, 2014) A new study published in ... egg production has increased over the past 50 years, the ... footprint. Researchers conducted a lifecycle analysis of U.S. egg production ... the complete lifecycle from crops to hens to the farm ...
... novel high-throughput screening process, scientists have for the first time ... a toxic eye protein that can lead to early onset ... can damage the eye,s optic nerve and cause vision loss ... for optic nerve damage. Researchers have implicated a ...
... the human gut and their impact on human health and ... research today. To address the most recent advances in this ... the world will come together at the Gut Microbiota for ... 9, 2014. The meeting is hosted by the Gut Microbiota ...
Cached Biology News:Landmark egg production study reveals reduction in environmental impact over past 50 years 2Landmark egg production study reveals reduction in environmental impact over past 50 years 3Researchers discover potential drug targets for early onset glaucoma 2Researchers discover potential drug targets for early onset glaucoma 3Attend the Gut Microbiota for Health World Summit 2014 2
(Date:1/15/2014)... January 15, 2014 Look inside the ... items for the lab, from fluid handling to instruments ... to ship when you order. , Preferred Solutions ... , from the L/S® model for precise flow control ...
(Date:1/15/2014)... This webinar will focus on EMA ... assessment in biosimilars. , Regulatory frameworks are evolving many ... however the complex nature of biopharmaceuticals makes the demonstration ... extremely challenging. Based on the specific aspects of biosimilar ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 The Microcompetition with ... major disease. One of these latent viruses is the Epstein ... arthritis (RA). Rheumatoid arthritis (RA) is a chronic inflammatory disease ... a study found that RA patients have high concentrations of ...
(Date:1/15/2014)... AudioNotch is the internet's leading provider of Notched Sound ... Patients listen to sound therapy that is tailor-made for ... to months, their tinnitus volume decreases. , AudioNotch has previously ... Notched White Noise. Now, AudioNotch is pleased to announce to ...
Breaking Biology Technology:Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3
... for a moment that Silicon Graphics Inc. (better ... days before its Altix 3000 family of servers and superclusters ... SGI rolled out the latest version of its popular ... the Mountain View-based company, whose only manufacturing facility is in ...
... Internet programming? Is tech still an exciting space to work ... with computers was an introductory programming class in 1979 using ... fledgling Internet when I started college in 1985. There have ... programming and the business of information technology as interesting and ...
... giant Eli Lilly & Company recently expressed concern to ... HIPAA privacy rule may impede clinical research trials. , ... and approve thousands of patient authorizations for use and ... Crosley, chief privacy officer of Indianapolis-based Eli Lilly. ...
Cached Biology Technology:SGI, Introduces Powerful High End Visualization Tools 2SGI, Introduces Powerful High End Visualization Tools 3Interview: Billpoint Founder Jason May on eBay, Open Source 2Interview: Billpoint Founder Jason May on eBay, Open Source 3Interview: Billpoint Founder Jason May on eBay, Open Source 4
...
... T4 DNA Ligase catalyzes the formation ... ATP between double-stranded DNAs with 3' hydroxyl ... DNA Ligase buffer optimizes ligation which can ... nucleic acids are not substrates for this ...
Bovine Renal Artery Smooth Muscle Cells (BRASMC) (>500,000 cells)...
... The Finnpipette BioControl is a ... technology. A complete liquid handling system ... twelve interchangeable tip cone modules. All ... tip cone modules fit one handle. ...
Biology Products: