Navigation Links
Pattern of drinking affects the relation of alcohol intake to coronary heart disease
Date:12/2/2010

A fascinating study published in the BMJ shows that although the French drink more than the Northern Irish each week, as they drink daily, rather than more on less occasions, the French suffered from considerably less coronary heart disease than the Northern Irish. Ruidavets and colleagues compared groups of middle aged men in France and Northern Ireland, who have very different drinking cultures and rates of heart disease.The authors found that men who "binge" drink (drink =50 g of alcohol once a week) had nearly twice the risk of myocardial infarction or death from coronary disease compared with regular drinkers over 10 years of follow-up. Similarly abstainers were at higher risk. 9,778 men aged 50-59, free of ischaemic heart disease at baseline, were recruited between 1991 and 1994. A total of 2,405 men from Belfast and 7,373 men from the French centres were included in the analyses.

The investigators related weekly alcohol consumption, incidence of binge drinking (alcohol >50 g on at least one day a week), incidence of regular drinking (at least one day a week, and alcohol < 50 g if on only one occasion), volume of alcohol intake, frequency of consumption, and types of beverage consumed to risk of coronary heart disease (CHD) events over a 10 year follow-up period. Overall, 60.5% of subjects from N. Ireland and 90.6% of French reported drinking alcohol at least once a week. Among drinkers, 12% of men in Belfast drank alcohol every day compared with 75% of men in France. Mean alcohol consumption was 22.1 g/ day in Belfast and 32.8 g/day in France. Binge drinkers comprised 9.4% and 0.5% of the Belfast and France samples, respectively.

Results showed that, after multivariate adjustment, the hazard ratio for hard CHD events compared with regular drinkers was 1.97 (95% CI 1.21 - 3.22) for binge drinkers, 2.03 (95% CI 1.41 - 2.94) for never drinkers, and 1.57 (95% CI 1.11 - 2.21) for former drinkers. The hazard ratio for hard CHD events in Belfast compared with in France was 1.76 (95% CI 1.37 to 2.67) before adjustment, and 1.09 (95% CI 0.79 to 1.50) after adjustment for alcohol patterns and wine drinking, indicating that most of the differences between the rates in the two countries were related to these two factors. Irrespective of country, only wine drinking was associated with a lower risk of hard coronary events.

The authors conclude that regular and moderate alcohol intake throughout the week, the typical pattern in middle-aged men in France, is associated with a low risk of ischemic heart disease, whereas the binge drinking pattern more prevalent in Belfast confers a higher risk.

Comments: While a strong inverse association between moderate alcohol consumption and cardiovascular disease has been demonstrated for decades, more recent research has emphasized the importance of the pattern of drinking (regular moderate versus episodic or binge drinking). Further, there continues to be debate about the potential greater effect of wine versus other beverages containing alcohol. This study shows that regular moderate drinking (especially of wine) is associated with lower risk of MI, but episodic or binge drinking increases the risk. Lifetime abstinence has a similar adverse relation to CHD as does episodic or binge drinking.


'/>"/>

Contact: R. Curtis Ellison
Ellison@bu.edu
508-333-1256
Boston University Medical Center
Source:Eurekalert

Related biology news :

1. The lifeblood of leaves: Vein networks control plant patterns
2. Research links damaged organs to change in biochemical wave patterns
3. Overweight children have different eating patterns than normal weight children
4. UF research gives clues about carbon dioxide patterns at end of Ice Age
5. Understanding behavioral patterns: Why bird flocks move in unison
6. Marriage patterns drive fertility decline
7. UCLA stem cell researchers uncover previously unknown patterns in DNA methylation
8. Concealed patterns beneath lifes variety
9. Tufts wins NCRR grant for Collaborative Cluster in Genome Structure and Developmental Patterning
10. Climate change and mountain building led to mammal diversity patterns
11. Study provides new insights into the implications of autism onset patterns
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/22/2016)... ANGELES , June 22, 2016 /PRNewswire/ ... identity management and verification solutions, has partnered ... edge software solutions for Visitor Management, Self-Service ... provides products that add functional enhancements ... partnership provides corporations and venues with an ...
(Date:6/16/2016)... , June 16, 2016 ... size is expected to reach USD 1.83 billion ... Grand View Research, Inc. Technological proliferation and increasing ... applications are expected to drive the market growth. ... , The development of advanced multimodal ...
(Date:6/7/2016)...  Syngrafii Inc. and San Antonio Credit Union ... integrating Syngrafii,s patented LongPen™ eSignature "Wet" solution into ... result in greater convenience for SACU members and ... existing document workflow and compliance requirements. ... Highlights: ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... -- Liquid Biotech USA , Inc. ... Research Agreement with The University of Pennsylvania ("PENN") ... patients.  The funding will be used to assess ... outcomes in cancer patients undergoing a variety of ... to support the design of a therapeutic, decision-making ...
(Date:6/24/2016)... , ... June 24, 2016 , ... While the majority ... as the Cary 5000 and the 6000i models are higher end machines that use ... height of the spectrophotometer’s light beam from the bottom of the cuvette holder. ...
(Date:6/23/2016)... 2016   Boston Biomedical , an industry ... to target cancer stemness pathways, announced that its ... Drug Designation from the U.S. Food and Drug ... including gastroesophageal junction (GEJ) cancer. Napabucasin is an ... cancer stemness pathways by targeting STAT3, and is ...
(Date:6/23/2016)... MA (PRWEB) , ... June 23, 2016 , ... ... Peel Plate® YM (Yeast and Mold) microbial test has received AOAC Research Institute ... platform of microbial tests introduced last year,” stated Bob Salter, Vice President of ...
Breaking Biology Technology: