Navigation Links
Pattern of drinking affects the relation of alcohol intake to coronary heart disease
Date:12/2/2010

A fascinating study published in the BMJ shows that although the French drink more than the Northern Irish each week, as they drink daily, rather than more on less occasions, the French suffered from considerably less coronary heart disease than the Northern Irish. Ruidavets and colleagues compared groups of middle aged men in France and Northern Ireland, who have very different drinking cultures and rates of heart disease.The authors found that men who "binge" drink (drink =50 g of alcohol once a week) had nearly twice the risk of myocardial infarction or death from coronary disease compared with regular drinkers over 10 years of follow-up. Similarly abstainers were at higher risk. 9,778 men aged 50-59, free of ischaemic heart disease at baseline, were recruited between 1991 and 1994. A total of 2,405 men from Belfast and 7,373 men from the French centres were included in the analyses.

The investigators related weekly alcohol consumption, incidence of binge drinking (alcohol >50 g on at least one day a week), incidence of regular drinking (at least one day a week, and alcohol < 50 g if on only one occasion), volume of alcohol intake, frequency of consumption, and types of beverage consumed to risk of coronary heart disease (CHD) events over a 10 year follow-up period. Overall, 60.5% of subjects from N. Ireland and 90.6% of French reported drinking alcohol at least once a week. Among drinkers, 12% of men in Belfast drank alcohol every day compared with 75% of men in France. Mean alcohol consumption was 22.1 g/ day in Belfast and 32.8 g/day in France. Binge drinkers comprised 9.4% and 0.5% of the Belfast and France samples, respectively.

Results showed that, after multivariate adjustment, the hazard ratio for hard CHD events compared with regular drinkers was 1.97 (95% CI 1.21 - 3.22) for binge drinkers, 2.03 (95% CI 1.41 - 2.94) for never drinkers, and 1.57 (95% CI 1.11 - 2.21) for former drinkers. The hazard ratio for hard CHD events in Belfast compared with in France was 1.76 (95% CI 1.37 to 2.67) before adjustment, and 1.09 (95% CI 0.79 to 1.50) after adjustment for alcohol patterns and wine drinking, indicating that most of the differences between the rates in the two countries were related to these two factors. Irrespective of country, only wine drinking was associated with a lower risk of hard coronary events.

The authors conclude that regular and moderate alcohol intake throughout the week, the typical pattern in middle-aged men in France, is associated with a low risk of ischemic heart disease, whereas the binge drinking pattern more prevalent in Belfast confers a higher risk.

Comments: While a strong inverse association between moderate alcohol consumption and cardiovascular disease has been demonstrated for decades, more recent research has emphasized the importance of the pattern of drinking (regular moderate versus episodic or binge drinking). Further, there continues to be debate about the potential greater effect of wine versus other beverages containing alcohol. This study shows that regular moderate drinking (especially of wine) is associated with lower risk of MI, but episodic or binge drinking increases the risk. Lifetime abstinence has a similar adverse relation to CHD as does episodic or binge drinking.


'/>"/>

Contact: R. Curtis Ellison
Ellison@bu.edu
508-333-1256
Boston University Medical Center
Source:Eurekalert

Related biology news :

1. The lifeblood of leaves: Vein networks control plant patterns
2. Research links damaged organs to change in biochemical wave patterns
3. Overweight children have different eating patterns than normal weight children
4. UF research gives clues about carbon dioxide patterns at end of Ice Age
5. Understanding behavioral patterns: Why bird flocks move in unison
6. Marriage patterns drive fertility decline
7. UCLA stem cell researchers uncover previously unknown patterns in DNA methylation
8. Concealed patterns beneath lifes variety
9. Tufts wins NCRR grant for Collaborative Cluster in Genome Structure and Developmental Patterning
10. Climate change and mountain building led to mammal diversity patterns
11. Study provides new insights into the implications of autism onset patterns
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/25/2016)... , Jan. 25, 2016  Glencoe Software, the world-leading ... and publication industries, will provide the data management solution ... (NPSC). ... Phenotypic analysis measures the ... organisms, allowing comparisons between states such as health and ...
(Date:1/21/2016)... India , January 21, 2016 ... According to a new market research report "Emotion Detection ... and Others), Software Tools (Facial Expression, Voice Recognition ... Regions - Global forecast to 2020", published by ... is expected to reach USD 22.65 Billion by ...
(Date:1/20/2016)... Jan. 20, 2016  Synaptics Incorporated (NASDAQ: ... solutions, today announced sampling of S1423, its newest ... and small screen applications including smartwatches, fitness trackers, ... round and rectangular shapes, as well as thick ... with moisture on screen, while wearing gloves, and ...
Breaking Biology News(10 mins):
(Date:2/11/2016)...  Neurocrine Biosciences, Inc. (NASDAQ: NBIX ) today announced its ... --> --> For the ... $29.3 million, or $0.34 loss per share, compared to a net ... same period in 2014. For the year ended December 31, 2015, ... loss per share, as compared to a net loss of $60.5 ...
(Date:2/11/2016)... ATLANTA , Feb. 11, 2016  Wellcentive ... a Portland, Oregon -based community ... to provide population health analytics, quality reporting and ... help FamilyCare strengthen its team of quality managers, ... reporting to the provider groups serving FamilyCare members. ...
(Date:2/11/2016)... ... February 11, 2016 , ... Reichert Technologies, which has ... to pursue the highest level of accuracy and quality with the addition of ... the AR5 Refractometer. Accurate, reliable and tough enough for the most demanding ...
(Date:2/10/2016)... , Feb. 10, 2016  The Maryland House ... , has announced that University of Maryland School of ... MBA and University of Maryland Medical System President and ... the "Speaker,s Medallion," the highest honor given to the ... Delegates. Dean Reece and Mr. Chrencik ...
Breaking Biology Technology: