Navigation Links
Patients with bowel disease eager to test 'fecal' therapy
Date:6/2/2011

The first study of the social and ethical issues associated with a provocative approach to treatment for ulcerative colitis has found that the majority of potential patients are eager for what is now called "fecal microbiota transplantation" to become available, although many have concerns about donor selection, screening, and methods of delivery.

Bacterial aggregates derived from fecal matter have been used sporadically to treat gastrointestinal disease for more than 50 years. These were often last-ditch efforts aimed at restoring microbial balance for patients with raging intestinal infections. More recently, the approach has produced lasting remissions for a small number of patients with a common disease: ulcerative colitis.

"Once patients get past the yuck factor they find the concept appealing," said study author David Rubin, MD, associate professor of medicine at the University of Chicago. "They perceive it as 'natural,' similar to probiotics. Patients with severe inflammatory bowel disease tend to develop a high tolerance for therapies that others might consider unorthodox."

Fecal microbiota transplantation (FMT)also known as fecal bacteriotherapy, among other namesis an effort to calm a troubled bowel by reintroducing the vast diversity of collaborative bowel inhabitants after the usual mix has been disturbed. More than 1,000 different strains of bacteria co-exist peacefully in the typical healthy bowel. But when the delicate balance is altered, by antibiotics or other causes, a few strains can become dominant, leading to severe diarrhea, inflammation and tissue damage.

The first FMT cases, dating back to 1958, were used to treat life-threatening infections caused by aggressive bacteria that had overwhelmed the bowel, driving out the competition. When antibiotics were unable to control the infection, physicians were able to restore balance by injecting the full range of gut bacteria. They did this by collecting fecal
'/>"/>

Contact: John Easton
john.easton@uchospitals.edu
773-702-6241
University of Chicago Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. A drug combination extends survival in refractory lung cancer patients
2. The use of placebo in rheumatoid arthritis clinical trials may negatively impact patients
3. Arthritis patients taking newer treatments do not have an overall increased cancer risk
4. Undertreatment of cardiovascular disease in rheumatoid arthritis patients following a heart attack
5. Study shows the HPV vaccine Gardasil doesnt increase disease activity in SLE patients
6. Inability to cry in patients with Sjogrens syndrome affect emotional and mental well-being
7. Targeted adalimumab treatment can optimize long-term outcomes for patients with early RA
8. Heart Failure: Targeting the right patients for CRT-D
9. Zebrafish models identify high-risk genetic features in leukemia patients
10. Following trail of cell death in epilepsy patients to find ways to preserve brain health
11. Combination therapy provides hope for cure of dangerous infections of cystic fibrosis patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... commerce market, reminds investors and media that  Mr. David ... CARTES SECURE CONNEXIONS AMERICA 2015, held in Washington ... three-day conference is organized into a series of nine session ... Global Fraud: Where is the Trust in Cyberspace? and ...
(Date:4/27/2015)... , Apr. 27, 2015 NXT-ID, Inc. ... biometric authentication company focused on the growing mobile commerce ... shipping to pre-order customers the first week of May, ... the month of May. Gino ... significant milestone for the company as Wocket® enters the ...
(Date:4/21/2015)... , April 21, 2015 ... evolving government policies are boosting access control systems market ... According to a recently published report by TechSci ... 2020 ", the access control systems market in ... USD1.2 billion by 2020.The access control systems market in ...
Breaking Biology News(10 mins):NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3
... the brain can come under attack in patients with multiple ... an MS-like disease, the brain,s response to a protein produced ... or cerebellum that comes under fire. The studyfrom researchers at ... Washington University in St. Louiswill be published online on October ...
... possible explanation for why people who eat more fruit and ... They have shown that a fragment released from pectin, found ... to inhibit galectin 3 (Gal3), a protein that plays a ... for the anticancer effects of foods are based on population ...
... journal (October 12th) reveals how scientists from the ... a novel nanomechanical approach to investigate the workings of ... used to combat increasingly resistant infections such as MRSA. ... Gabriel Aeppli, developed ultra-sensitive probes capable of providing new ...
Cached Biology News:Pectin power 2Nanotechnology boosts war on superbugs 2
(Date:5/21/2015)... , May 21, 2015 /PRNewswire/ - SQI Diagnostics Inc. ... sciences company that develops and commercializes proprietary technologies and ... and operational results for the second fiscal quarter ended ... the Company continued to advance business with our existing ... Morris , President and CEO of SQI. "The delivery ...
(Date:5/21/2015)... (PRWEB) May 21, 2015 uBiome, ... announced a partnership with PicnicHealth, a healthcare company ... Participants diagnosed with Inflammatory Bowel Disease (IBD) will ... a complementary uBiome research kit. Both companies were ... , For more information on this ...
(Date:5/21/2015)... 2015  CytRx Corporation (NASDAQ: CYTR ), ... oncology, today announced positive updated results from its ... the treatment of unresectable glioblastoma multiforme (GBM), a ... trial is designed to investigate the preliminary efficacy ... have progressed following prior treatment with surgery, radiation ...
(Date:5/21/2015)... May 21, 2015 Tunnell Consulting, ... the firm as senior statistician and Principal, a position ... experience in the management and analysis of complex and ... chemical industries. , “We’re delighted to have Julia join ... data analytics,” said Dr. Philippe Cini, Group Vice President ...
Breaking Biology Technology:SQI Diagnostics Reports Second Quarter Financial Results 2SQI Diagnostics Reports Second Quarter Financial Results 3SQI Diagnostics Reports Second Quarter Financial Results 4SQI Diagnostics Reports Second Quarter Financial Results 5SQI Diagnostics Reports Second Quarter Financial Results 6SQI Diagnostics Reports Second Quarter Financial Results 7SQI Diagnostics Reports Second Quarter Financial Results 8uBiome Partners with PicnicHealth 2uBiome Partners with PicnicHealth 3CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 2CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 3CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 4CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 5CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 6CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 7Julia O’Neill Joins Tunnell Consulting’s Operational and Process Improvement Practice 2
... composed of gold nanoparticles and viral particles, woven together ... structure a distinctive mix of hard, metallic nanoparticles ... the very stuff of life, DNA marks a ... of materials to create infinitesimal devices. The research, ...
... Corporation (NYSE: WAT ) today announced ... 7.1 Service Release 7 (SR-7), structurally validated to ... 32bit versions, and Waters new Empower™ 3 Chromatography ... NuGenesis SDMS 7.1 release features new functionality for ...
... Misaligned research, medical challenges and harsh economics are thwarting ... in the United States, according to a trio of ... (Jan. 27) issue of the journal Neuron . ... preventive strategies are being tested in patients firmly in ...
Cached Biology Technology:A mix of tiny gold and viral particles -- and the DNA ties that bind them 2Waters Releases NuGenesis SDMS 7.1 Validated to Support Windows 7 and Empower 3 CDS 2Course correction needed for Alzheimer's therapies, experts warn 2Course correction needed for Alzheimer's therapies, experts warn 3