Navigation Links
Pathway found that lets mosquitoes fatten up, slow down for winter
Date:4/24/2008

COLUMBUS, Ohio Two genes that help insulin regulate mosquitoes growth have been identified as key contributors to how the insects enter a dormant state to survive winters cold.

The research finding broadens the understanding of the mosquito life cycle and appears to shed some light on how other insects and invertebrate species weather the winter months.

The shorter days of autumn trigger certain species of mosquitoes into diapause, a hibernation-like state of arrested development that allows them to survive through the winter. But this new research has determined that a hormonal response is behind the mosquitos ability to store up extra fat and halt reproductive activity in preparation for its months-long dormancy, said David Denlinger, senior author of the study and professor of entomology at Ohio State University.

The research appears online this week in the Proceedings of the National Academy of Sciences.

Denlingers lab is working with Culex pipiens, a common mosquito in the United States and the species that carries the West Nile virus in North America. He and colleagues have identified several genes in this mosquito that function within the insulin signaling pathway, the mechanism necessary for diapause to begin. However, they focused on two genes that appear to have the most power in regulating the insects transition into a dormant state.

Were trying to decipher this whole pathway how the shortening days signal the hormonal shifts that tell mosquitoes to halt development, Denlinger said.

By disrupting the functions of these two genes, the scientists were able to both mimic hormonal circumstances that initiate diapause as well as disrupt fat retention during diapause pointing to a separate function for each gene.

While the point at this stage is fully understanding the intricacies of this life cycle, the findings could someday lead to methods to manipulate mosquito populations so they nev
'/>"/>

Contact: David Denlinger
Denlinger.1@osu.edu
614-292-8209
Ohio State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Proteins that stop a major signaling pathway can also generate new proteins
2. Stem cells and cancer: cancer pathways that also control the adult stem cell population
3. Researcher discovers pathway plants use to fight back against pathogens
4. Newly defined signaling pathway could mean better biofuel sources
5. MIT applies engineering approach to studying biological pathways
6. Researchers reveal HIV peptides possible pathway into the cell
7. Paired microbes eliminate methane using sulfur pathway
8. Rong Li Lab reports protein interactions of MAP kinase signaling pathway
9. Salk scientists identify key nerve navigation pathway
10. Study identifies pathway required for normal reproductive development
11. Old developmental pathways spawn revolutionary evolutionary changes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... Yale University researchers are studying a potential new treatment ... disease in which scars develop in the lungs and ... mimic, miR-29, which is delivered to lung tissue intravenously. ... it reversed fibrosis after several days. , The ... EMBO Molecular Medicine . , "The mimic, when injected ...
(Date:9/22/2014)... Rochelle, NY, September 22, 2014Cassava, also known as tapioca, ... yields in areas of Africa, Asia, and Latin America ... the availability of novel enzymes and processes designed to ... be used to produce sweeteners such as glucose, fructose, ... to corn, as described in a Review article in ...
(Date:9/22/2014)... Antarctic fishes that manufacture their own "antifreeze" ... also suffer an unfortunate side effect, researchers report: ... bodies resist melting even when temperatures warm. ... Proceedings of the National Academy of Sciences . ... undesirable consequence of the evolution of antifreeze proteins ...
Breaking Biology News(10 mins):Reversing the effects of pulmonary fibrosis 2Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 2Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 3
... single dose of gene-virus combination cured rats of a ... causes the accumulation of bilirubin –which, untreated, results in ... of Medicine in a report in the Proceedings of ... first time this disease (Crigler-Najjar syndrome) has been completely ...
... new approach to predict whether a drug in development ... could get antibiotics to market faster and more cheaply, ... scientists worldwide have sounded the alarm: There simply aren’t ... adept at outwitting the traditional antibiotic arsenal. , Yet ...
... variation that may increase susceptibility to osteoporosis, a new study ... Louis demonstrated that in women the variant gene speeds up ... in the bones of the hip. , The study will ... Bone and Mineral Research and is available online. , ...
Cached Biology News:Gene Therapy Cures Inherited Liver Disease In Rats 2New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal 2New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal 3New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal 4Increased risk of osteoporosis associated with gene that one in five people have 2
(Date:9/22/2014)... Platelets, the tiny cell fragments whose job it is ... a cell nucleus. But they can "feel" the physical ... have discovered. , Platelets respond to surfaces with greater ... they "turn on" other platelets and other components of ... smarter than we give them credit for, in that ...
(Date:9/22/2014)... a way to create a highly sensitive chemical sensor ... imperfections have unique electronic properties that the researchers were ... molecules by 300 times. , The study is available ... . , Amin Salehi- Khojin, asst professor of mechanical ... graduate student and Bijandra Kumar, post doc where they ...
(Date:9/22/2014)... Topical BioMedics, Inc., is celebrating 20 years ... suffering, restoring hope an quality of life and contributing ... because of the innovative cellular biomedicines research that made ... , The company was founded in 1994 in ... chief of research, and Topricin inventor), Aurora Paradise (COO) ...
(Date:9/22/2014)... 2014 Invisible Sentinel Inc., a ... food and beverage industries, announced today that its ... a non-exclusive agreement by Enartis, a global provider ... an Esseco Group company headquartered in Trecate, Italy, ... and other global markets for their own in-winery ...
Breaking Biology Technology:Platelets modulate clotting behavior by 'feeling' their surroundings 2Graphene imperfections key to creating hypersensitive 'electronic nose' 2Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 2Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 3Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 4Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 5Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 6Invisible Sentinel's Test for Wine-Spoilage Microbe to be Distributed by Enartis in Multiple Markets Globally 2Invisible Sentinel's Test for Wine-Spoilage Microbe to be Distributed by Enartis in Multiple Markets Globally 3
... Matrox Graphics Inc., the leading,manufacturer of specialized ... Matrox Xenia(TM) Series display controller boards with its,ME/CCL ... first native PCI Express single-slot board with,all-digital, triple-monitor ... configuration. Xenia Series supports resolutions from <1MP to,8MP ...
... Pressure,BioSciences, Inc. (Nasdaq: PBIO ) ("PBI") today ... presentation of favorable data,generated by scientists at Amgen, ... scheduled presentation by Dr. Paul Pevsner of the,NYU ... in identifying potential protein,biomarkers in colon cancer samples, ...
... 8 Transcept Pharmaceuticals,Inc., a privately-held specialty pharmaceutical ... President and Chief Financial Officer,is scheduled to present ... in New York City on Monday, October 13, ... webcast of the presentation will be available at, ...
Cached Biology Technology:Totoku Europe Chooses Matrox Xenia(TM) Series to Drive Medical Monitors 2Pressure BioSciences, Inc. Provides Corporate Update 2Pressure BioSciences, Inc. Provides Corporate Update 3Pressure BioSciences, Inc. Provides Corporate Update 4Transcept Pharmaceuticals, Inc. to Present at the Natixis Bleichroeder Second Annual Hidden Gems Conference 2
...
Ras-related C3 botulinum toxin substrate 1...
Human sVCAM-1/CD106 ELI-PAIR Kit...
HP 1 alpha Immunogen: Synthetic peptide between amino acids 1-100 of the human HP 1 alpha protein. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Biology Products: