Navigation Links
Pathogen virulence proteins suppress plant immunity
Date:4/21/2008

Blacksburg, Va. Researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech and their colleagues have identified a key function of a large family of virulence proteins that play an important role in the production of infectious disease by the plant pathogen Phytophthora sojae.

VBI Professor Brett Tyler and members of his research group, along with researchers from Virginia Techs Department of Plant Pathology, Physiology and Weed Science, Nanjing Agricultural University in China, and Wageningen University in The Netherlands, examined the function of the virulence (or effector) protein Avr1b in P. sojae and discovered that Avr1b is capable of suppressing an important process in plant immunity called programmed cell death. Programmed cell death is an in-built suicide mechanism that kills infected plant tissue and fills it with toxins so the pathogen can no longer feed on it. The work appears in the advance online edition of The Plant Cell. (1)

P. sojae is an oomycete plant pathogen that causes severe damage to soybean crops, resulting in $1-2 million in annual losses for commercial farmers in the United States and much more worldwide. By changing key amino acid residues in the effector protein, the researchers were able to attribute the cause of the suppression of programmed cell death to the presence of two conserved sequences (dubbed W and Y motifs) at one particular end of the protein, the C-terminus. These amino acid sequences are also present in many other members of a huge virulence gene superfamily that Tylers group found recently in oomycete pathogens. (2)

According to VBI Professor Brett Tyler, Our results suggest that, like many human viruses such as HIV, oomycete plant pathogens disable the immune systems of their victims as part of their infection strategy.


'/>"/>
Contact: Susan Bland
subland@vbi.vt.edu
540-231-7912
Virginia Tech
Source:Eurekalert

Page: 1

Related biology news :

1. Understanding, combating foodborne pathogens E. coli 0157 and salmonella
2. New magnetic separation technique might detect multiple pathogens at once
3. New system would use rotating magnetic field to detect pathogens
4. K-State specialist in tick-borne pathogens receives $1.8 million grant
5. Pathogens use previously undescribed mechanism to sabotage host immune system
6. Can interacting pathogens explain disease patterns?
7. Breakthrough research turns the tide on water-borne pathogen
8. Tomato pathogen genome may offer clues about bacterial evolution at dawn of agriculture
9. Technology uses live cells to detect food-borne pathogens, toxins
10. Researcher discovers pathway plants use to fight back against pathogens
11. Tomato pathogen genome may offer clues about bacterial evolution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/25/2016)... , Jan. 25, 2016   Unisys Corporation (NYSE: ... at John F. Kennedy (JFK) International Airport, New York ... (CBP) identify imposters attempting to enter the United ... belong to them. pilot testing of the system ... at three terminals at JFK during January 2016. --> ...
(Date:1/20/2016)... , Jan. 20, 2016 A market that ... directly benefit from the explosion in genomics knowledge. Learn ... Sound Research. A range of dynamic trends are pushing ... - personalized medicine - pharmacogenomics - pathogen evolution - ... large markets - greater understanding of the role of ...
(Date:1/13/2016)... , January 13, 2016 ... published a new market report titled - Biometric Sensors Market ... Forecast, 2015 - 2023. According to the report, the global biometric ... is anticipated to reach US$1,625.8 mn by 2023, expanding ... In terms of volume, the biometric sensors market is ...
Breaking Biology News(10 mins):
(Date:2/4/2016)... ... February 04, 2016 , ... ... and triple quad LC-MS, host live demos and poster sessions, and present on ... exhibition. The conference takes place March 6 to 10 at the Georgia World ...
(Date:2/4/2016)... YORK , February 4, 2016 ... QBIO), a biotechnology acceleration company is pleased to provide the ... --> Over the last 3 months we ... and securities purchase agreements exceeding $1,000,000. As a result, we ... our Mannin Research Inc. license agreement and expect that development ...
(Date:2/4/2016)... , February 4, 2016 ... Laboratories (ABL), Inc. --> Strasbourg, France ... --> PharmaVentures is pleased to announce that it ... its biopharmaceutical manufacturing unit in Strasbourg, France ... --> --> Transgene (Euronext: ...
(Date:2/3/2016)... Ascendis Pharma A/S (Nasdaq: ASND ), ... TransCon technology to address significant unmet medical needs, today ... Leerink Partners Global Healthcare Conference Location: , Waldorf ... 2016 Time:  , 11:55am EST www.ascendispharma.com ... An audio webcast of this event will be posted ...
Breaking Biology Technology: