Navigation Links
Pathogen virulence proteins suppress plant immunity
Date:4/21/2008

Blacksburg, Va. Researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech and their colleagues have identified a key function of a large family of virulence proteins that play an important role in the production of infectious disease by the plant pathogen Phytophthora sojae.

VBI Professor Brett Tyler and members of his research group, along with researchers from Virginia Techs Department of Plant Pathology, Physiology and Weed Science, Nanjing Agricultural University in China, and Wageningen University in The Netherlands, examined the function of the virulence (or effector) protein Avr1b in P. sojae and discovered that Avr1b is capable of suppressing an important process in plant immunity called programmed cell death. Programmed cell death is an in-built suicide mechanism that kills infected plant tissue and fills it with toxins so the pathogen can no longer feed on it. The work appears in the advance online edition of The Plant Cell. (1)

P. sojae is an oomycete plant pathogen that causes severe damage to soybean crops, resulting in $1-2 million in annual losses for commercial farmers in the United States and much more worldwide. By changing key amino acid residues in the effector protein, the researchers were able to attribute the cause of the suppression of programmed cell death to the presence of two conserved sequences (dubbed W and Y motifs) at one particular end of the protein, the C-terminus. These amino acid sequences are also present in many other members of a huge virulence gene superfamily that Tylers group found recently in oomycete pathogens. (2)

According to VBI Professor Brett Tyler, Our results suggest that, like many human viruses such as HIV, oomycete plant pathogens disable the immune systems of their victims as part of their infection strategy.


'/>"/>
Contact: Susan Bland
subland@vbi.vt.edu
540-231-7912
Virginia Tech
Source:Eurekalert

Page: 1

Related biology news :

1. Understanding, combating foodborne pathogens E. coli 0157 and salmonella
2. New magnetic separation technique might detect multiple pathogens at once
3. New system would use rotating magnetic field to detect pathogens
4. K-State specialist in tick-borne pathogens receives $1.8 million grant
5. Pathogens use previously undescribed mechanism to sabotage host immune system
6. Can interacting pathogens explain disease patterns?
7. Breakthrough research turns the tide on water-borne pathogen
8. Tomato pathogen genome may offer clues about bacterial evolution at dawn of agriculture
9. Technology uses live cells to detect food-borne pathogens, toxins
10. Researcher discovers pathway plants use to fight back against pathogens
11. Tomato pathogen genome may offer clues about bacterial evolution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/28/2017)... February 28, 2017 News solutions for biometrics, ... ... from 14 to 16 March, Materna will present its ... how seamless travel is a real benefit for passengers. To ... to their passenger touch point solutions to take passengers through the ...
(Date:2/27/2017)... --  Strategic Cyber Ventures , the industry,s first cybersecurity ... million investment in  Polarity , the first commercial human ... based and is led by cybersecurity veterans Tom ... Gula , also a longtime cybersecurity veteran and founder ... A round of funding. This new funding will be ...
(Date:2/24/2017)... , Feb. 24, 2017  EyeLock LLC, a leader of ... elite iris biometric solution on the latest Qualcomm® ... at Mobile World Congress 2017 (February 27 ... in Hall 3, Stand 3E10. ... Haven™ security platform—a combination of hardware, software ...
Breaking Biology News(10 mins):
(Date:3/28/2017)... , ... March 28, 2017 , ... ... and diminished effectiveness over time. A recent study published in STEM CELLS suggests ... stimulating subventricular zone (SVZ) stem cells to produce more neural cells. , ...
(Date:3/28/2017)... , March 28, 2017 /PRNewswire/ -RepliCel Life Sciences Inc. (OTCQB: ... to report compelling safety and clinical data from its phase ... 1 collagen-expressing, hair follicle-derived fibroblasts (RCT-01) as a treatment for ... ... a complete safety profile at 6 months and showed no ...
(Date:3/27/2017)... WARREN, N.J. , March 27, 2017 Roka ... providing advanced testing solutions for the detection of foodborne pathogens, ... at the Sidoti & Company Spring 2017 Convention on March ... the New York Marriott Marquis. About Roka ... ...
(Date:3/27/2017)... ... March 27, 2017 , ... Biopsies from ... heterogeneous samples with limited tumor content in a large background of normal or ... as the need for reliable detection of low abundance somatic mutations, particularly in ...
Breaking Biology Technology: