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Passing the Gac
Date:10/29/2013

encoded by Tn6188, termed QacH by Schmitz-Esser and colleagues term because of its similarity to proteins of this name from other organisms, was activated by the presence of BC in culture medium. And in a final experiment, the scientists could show that deleting the QacH gene made listeria once again sensitive to the drug.

Although his group has not formally proved that the new transposon is responsible for BC resistance in listeria, Schmitz-Esser feels that he has "probably sufficient circumstantial evidence to obtain a conviction. In any case our results show that listeria can acquire new genetic material from other bacteria it is thus important to ensure thorough disinfecting of food-processing facilities to prevent reservoirs of resistant bacteria building up and transferring their resistance to listeria."


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Contact: Susanna Kautschitsch
susanna.kautschitsch@vetmeduni.ac.at
43-125-077-1153
University of Veterinary Medicine -- Vienna
Source:Eurekalert  

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Passing the Gac
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