Navigation Links
Parents' stress leaves lasting marks on children’s genes: UBC-CFRI research
Date:8/30/2011

Researchers at the University of British Columbia and the Child & Family Research Institute have shown that parental stress during their children's early years can leave an imprint on their sons' or daughters' genes an imprint that lasts into adolescence and may affect how these genes are expressed later in life.

The study, published online today in the journal Child Development, focused on epigenetics the expression of genes as opposed to the underlying sequence of DNA. A central component of epigenetics is methylation, in which a chemical group attaches to parts of the DNA a process that acts like a dimmer on gene function in response to social and physical environments.

Michael S. Kobor, a UBC associate professor of medical genetics, measured methylation patterns in cheek cell DNA collected recently by University of Wisconsin researchers from more than 100 adolescents. These patterns were compared to data obtained by the University of Wisconsin in 1990 and 1991, when these same children were infants and toddlers, and their parents were asked to report on their stress levels including depression, family-expressed anger, parenting stress and financial stress.

Comparing DNA methylation to stress, Kobor's team found that higher stress levels reported by mothers during their child's first year correlated with methylation levels on 139 DNA sites in adolescents. They also discovered 31 sites that correlated with fathers' higher reported stress during their child's pre-school years (three-and-a-half to four-and-a-half years old).

"To our knowledge, this is the first demonstration, using carefully collected longitudinal data, that parental adversity during a child's first years leads to discernible changes in his or her 'epigenome,' measurable more than a decade later," says Kobor, a scientist at the Centre for Molecular Medicine and Therapeutics at the Child and Family Research Institute (CFRI), and a Mowafaghian Sch
'/>"/>

Contact: Brian Kladko
brian.kladko@ubc.ca
778-838-4169
University of British Columbia
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mutations not inherited from parents cause more than half the cases of schizophrenia
2. Opposites may attract, but they dont make better parents
3. Parents social problems affect their children -- even in birds
4. Study recommends that parents, physicians share decisions in sex development disorder surgery
5. Penguin males with steady pitch make better parents
6. Doctors can influence when parents wean children from bottle, study finds
7. UNC study: Color-coded chart improves parents understanding of body mass index
8. Work conditions impact parents food choices
9. Scripps Research scientists help pinpoint cause of stress-related DNA damage
10. At last, a reason why stress causes DNA damage
11. Penn molecular scientists develop color-changing stress sensor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... 31 de julho de 2015 A 10 ... ) será realizada pela BGI de 22-25 de outubro de ... A conferência está celebrando seu 10 o. ... ICG se tornou uma das reuniões mais influentes do ... científicos mais dinâmicos, entusiastas e prazerosos. ...
(Date:7/31/2015)... , 31 de julio de 2015 La 10 ... se celebrará por medio de BGI del 22 al 25 de ... Este año, la conferencia celebra su décimo ... ha convertido en una de las reuniones anuales más influyentes ... de las reuniones más dinámicas, entusiastas y mejores a nivel ...
(Date:7/31/2015)... 31, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market and creator of ... provisional patent 62/198989 for ELECTRONIC CRYPTO-CURRENCY MANAGEMENT ... method to advance crypto-currencies such as Bitcoin into the ... uniform way to manage all payments.  ...
Breaking Biology News(10 mins):A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 2A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 3La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 2La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 3NXT-ID Patents Electronic Crypto-Currency Management Technology 2NXT-ID Patents Electronic Crypto-Currency Management Technology 3NXT-ID Patents Electronic Crypto-Currency Management Technology 4
... A tiny difference in the coding pattern of a single ... drops with advancing age, investigators at the Stanford University School ... System have learned. In a study to be published ... tested the skills of experienced airplane pilots and found that ...
... eaten from silverware or worn copper jewelry, you,ve been ... into the environment, say scientists at the University of ... and the public have been concerned that the potential ... way of environmental exposure. Now, with the ...
... available in Spanish . The study, ... the result of an interdisciplinary collaboration between two researchers: one ... the area of geographic history under the direction of the ... is Consejo Superior de Investigaciones Cientficas (CSIC Spanish National ...
Cached Biology News:Gene variation predicts rate of age-related decline in mental performance, Stanford study 2Gene variation predicts rate of age-related decline in mental performance, Stanford study 3Gene variation predicts rate of age-related decline in mental performance, Stanford study 4Nanoparticles and their size may not be big issues 2Forest fires are becoming larger and more frequent 2
(Date:8/28/2015)... , Aug. 28, 2015 ... the addition of the "Global & USA BioSimilar ... The highly awaited US Biosimilar market will ... awaited filigrastim biologic, Zarxio. How will the global market ... author reveals that biosimilars could save the US economy ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... surgeon, Wade McKenna, DO, announced today that the use of sterile, dehydrated amniotic ... complete healing of an otherwise non-healing surgical knee wound. , The case involved ...
(Date:8/27/2015)... Aug. 27, 2015 /PRNewswire/ - Portage Biotech Inc. ... and Biohaven Pharmaceutical Holding Company Limited (Biohaven), announced ... I study of BHV-0223, a glutamate modulating agent. ... BHV-0223 and recently obtained clearance from the U.S. ... human testing. Portage holds 54% equity interest in ...
(Date:8/27/2015)... 2015 GlassesOff (OTCBB: GLSO), a visual ... the human vision system, announced today a partnership with eight-time ... Chris Paul to develop a new mobile app designed ... their real-life on-court performance. Vision is the inception ... shooting a ball or blocking a pass. The critical impact ...
Breaking Biology Technology:Global & USA BioSimilar Market Analysis Report 2015-2021 2Global & USA BioSimilar Market Analysis Report 2015-2021 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 2Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 4Portage's Biohaven doses first human subject in Phase 1 trial with lead drug candidate BHV-0223 2Portage's Biohaven doses first human subject in Phase 1 trial with lead drug candidate BHV-0223 3Portage's Biohaven doses first human subject in Phase 1 trial with lead drug candidate BHV-0223 4Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 2Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 3
... , ,So how many boards can you break with one ... you juggle at one time? Even more important what projects ... improve your organizations position in the marketplace? If not, read on, ... is a program of continuous improvement that focuses on customer requirements. ...
... Wis. Whenever a new piece of technology comes out ... an instant success. More frequently, it is seen as an ... adopters, who are often making a risky gamble. To become ... field, tested in real-world conditions and purchased enough so early ...
... Quintessence Biosciences, Inc. has formed a scientific ... of cancer therapeutics. , ,Announced last week by ... the board will consist of distinguished scientific leaders who ... Quintessence Biosciences, Inc. They will also assist the company ...
Cached Biology Technology:Part 6 Project Performance Get on the path to continuous improvement 2Part 6 Project Performance Get on the path to continuous improvement 3Part 6 Project Performance Get on the path to continuous improvement 4Laying the foundation for RFID 2Laying the foundation for RFID 3Laying the foundation for RFID 4Quintessence Biosciences forms cancer therapeutic advisory board 2
... Chromo4 real-time PCR detector is an optical ... a DNA Engine or Dyad Disciple gradient-capable ... a compact scanning photonics shuttle that contains ... 500-535 nm, 555-585 nm, 620-650 nm) and ...
... highly sensitive laser confocal systems designed for ... scanners that meet your expectations, differentiating between ... optimizing the signal on the bottom as ... range for increased sensitivity. Results with VersArray ...
... four slides. The new ArraySlide 24-4 chamber ... x 7mm) individual printing surfaces for multiple ... studies. Unlike other systems, this device utilizes ... of contaminating adhesives. The chamber itself is ...
... x 3 nmol (individual) with sequence ... specifically targeted to your target gene of interestis ... you get more than 75% knockdown of your ... nM siRNA for transfection and confirmation of optimal ...
Biology Products: