Navigation Links
Paper offers insights into network that plays crucial role in cell function and disease
Date:2/5/2014

w stathmin works. The experiments (primarily designed and performed by Kamlesh Gupta) present experimental evidence that stathmin can act directly on microtubules and it does so by binding and destabilizing segments of the assembling microtubule before they can be incorporated into the final microtubule structure. Accompanying computer simulations show that this type of molecular activity could produce the experimentally observed effects of microtubule dynamics.

"This work is significant because this disassembly process is essential for basic cell survival and because stathmin, also called oncoprotein 18, is dramatically over produced in a number of cancers," Alber said. "Understanding how the protein works is an important step towards figuring out how to inhibit it, which may provide a route for new anti-cancer drugs."


'/>"/>

Contact: Mark Alber
malber@nd.edu
574-631-8371
University of Notre Dame
Source:Eurekalert

Page: 1 2

Related biology news :

1. Two papers unraveled the mystery of sex determination and benthic adaptation of the flatfish
2. The Protein Society announces the selection of 2 Protein Science Best Paper speakers
3. Paper predicts a future without carnivores would be truly scary
4. Assessing dangerous climate change and call for climate change response papers
5. Paper-based device could bring medical testing to remote locales
6. Notre Dame paper sheds light on genetic and physiological basis for metabolic diseases
7. Managing waters shared across national boundaries: Treasury of papers helps capture 20 years of lessons
8. Does including parasites upset food web theory? Yes and no, says new paper
9. Stanford engineers monitor heart health using paper-thin flexible skin
10. New research paper says we are still at risk of the plague
11. Old records, new bees result in Science paper for MSU ecologist
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... Spain, France, and the U.S. has discovered and ... definitive member of the tribe Omaliini that has ... description were made possible through the use of ... allows the detailed study of otherwise invisible specimens ... in the journal Annals of the Entomological ...
(Date:7/31/2014)... photovoltaic effect in 1839, humankind has sought to further ... own purposes. In a new research report published in ... Journal , scientists may have uncovered a new ... on a naturally occurring combination of lipids that have ... time and across speciessuggests that this specific natural combination ...
(Date:7/31/2014)... Hibiscus flowers- they are an iconic symbol of ... in the landscape. Some, like Hawaii,s State Flower- ... Only a relatively few botanists and Hawaiian conservation ... and intriguing related group of plants known as ... Brother of Hibiscus species are in fact highly ...
Breaking Biology News(10 mins):Scientists shine bright new light on how living things capture energy from the sun 2Brother of Hibiscus is found alive and well on Maui 2
... millions the number of poor forced to seek new ... intense dust storms plaguing many areas menace the health ... a new report. , Thick storms rising out of ... Japan and even reduce air quality over North America, ...
... nerve cells to trees -- some are short and bushy ... branches coming out of one or two main trunks. Different ... to discover how these dissimilar patterns come about and why. ... Rutgers, The State University of New Jersey, examines the role ...
... today that regions of the human genome have been ... specific time-points during evolution. It appears that long periods ... accretion of duplicated DNA fragments, are "punctuated" by relatively ... time that such temporal bias has been documented for ...
Cached Biology News:Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades 2Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades 3Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades 4Snapin: A protein with therapy potential for autism 2'Punctuated' evolution in the human genome 2'Punctuated' evolution in the human genome 3
(Date:7/31/2014)... July 31, 2014 CollabRx, Inc. (NASDAQ: ... therapeutic decision-making in oncology, today announced that it will ... to discuss the Company's financial results for the first ... about the business in the current fiscal year. , ... on Thursday, August 14, 2014, at 5 p.m. EDT ...
(Date:7/31/2014)... Diego, CA (PRWEB) July 31, 2014 ... announced today the integration of Omicsoft’s Array Suite with ... both platforms will be able to send data in ... integration works with all versions of tranSMART including the ... the art statistics, visualization and storage for the analysis ...
(Date:7/31/2014)... SoundConnect , an award ... proud to announce the addition of Adobe Connects ... elearning tools to quickly deploy and manage online ... tools for desktop and mobile learning solutions. , ... perfect online training solution, enabling organizations to deploy, ...
(Date:7/30/2014)... PARIS , July 30, 2014  Regeneron ... NYSE: SNY) today announced that the Companies intend to ... pediatric disease priority review voucher in connection with the ... review voucher entitles the holder to designate a BLA ... review from the filing date instead of the standard ...
Breaking Biology Technology:CollabRx, Inc. Schedules First Quarter Fiscal Year 2015 Financial Conference Call and Business Update 2Rancho BioSciences, in Partnership with Omicsoft, have Integrated Array Suite with tranSMART 2Rancho BioSciences, in Partnership with Omicsoft, have Integrated Array Suite with tranSMART 3SoundConnect Enhances Portfolio with Adobe Connect Learning Management System (LMS) 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 4Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 5Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 6
... Ohio Scientists are using the engineering technology ... design 3-D models for the replacement of delicate ... or trauma. The researchers, combining engineering ... technique called topological optimization to design an experimental ...
... - Ocean Nutrition Canada (ONC) supplier of the most trusted source ... acquisition of the exclusive global marketing and distribution rights to GAT ... , , ... acquired the rights to exclusive use of GAT,s unique and patented ...
... NEW YORK , July 12 ... or the "Company"), an international,biopharmaceutical company with operations in ... has been awarded a $700,000 contract from ... Advanced Technology,Research Center (USAMRMC-TATRC) under U.S. Army Medical Research ...
Cached Biology Technology:High-performance engineering used to design facial bone replacements 2High-performance engineering used to design facial bone replacements 3Ocean Nutrition Canada Announces Acquisition of Exclusive License to GAT Food Essentials, Omega-3 Microencapsulation-Emulsion Technology 2Ocean Nutrition Canada Announces Acquisition of Exclusive License to GAT Food Essentials, Omega-3 Microencapsulation-Emulsion Technology 3NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 2NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 3NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 4NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 5
... Colorimetric Detection System is intended for use ... generated by an in-house validated in vitro ... of interest. • ... a hybridization capture assay designed to detect ...
... is optimized for maximum packaging efficiencies of cDNA ... l vector. Using a test insert with Novagen's ... (> 4 x 10^8 pfu/g ligated l control ... extremely easy to use; simply add up to ...
BD BioCoat Laminin 150 mm Culture Dishes...
MAb to Desmoplakin I & II Desmoplakin I & II...
Biology Products: