Navigation Links
Pancreatic cancers use fructose, common in the Western diet, to fuel their growth
Date:8/3/2010

Pancreatic cancers use the sugar fructose, very common in the Western diet, to activate a key cellular pathway that drives cell division, helping the cancer to grow more quickly, a study by researchers at UCLA's Jonsson Comprehensive Cancer Center has found.

Although it's widely known that cancers use glucose, a simple sugar, to fuel their growth, this is the first time a link has been shown between fructose and cancer proliferation, said Dr. Anthony Heaney, an associate professor of medicine and neurosurgery, a Jonsson Cancer Center researcher and senior author of the study.

"The bottom line is the modern diet contains a lot of refined sugar including fructose and it's a hidden danger implicated in a lot of modern diseases, such as obesity, diabetes and fatty liver," said Heaney, who also serves as director of the Pituitary Tumor and Neuroendocrine Program at UCLA. "In this study, we show that cancers can use fructose just as readily as glucose to fuel their growth."

The study appeared in the Aug. 1 issue of the peer-reviewed journal Cancer Research.

The source of fructose in the Western diet is high fructose corn syrup (HFCS), a corn-based sweetener that has been on the market since about 1970. HFCS accounts for more than 40 percent of the caloric sweeteners added to foods and beverages, and it is the sole sweetener used in American soft drinks.

Between 1970 and 1990, the consumption of HFCS in the U.S. has increased over 1,000 percent, according to an article in the April 2004 issue of the American Journal of Clinical Nutrition. Food companies use HFCS - a mixture of fructose and glucose - because it's inexpensive, easy to transport and keeps foods moist. And because it is so sweet, it's cost effective for companies to use small quantities of HCFS in place of more expensive sweeteners or flavorings.

In his study, Heaney and his team took pancreatic tumors from patients and cultured and grew th
'/>"/>

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. TGen-Asuragen partner to advance pancreatic cancer research
2. Predicting prognosis and treatment response in a subset of pancreatic cancer patients
3. Soft drink consumption may increase risk of pancreatic cancer
4. Oral COTI-2 is effective in a second animal model of human pancreatic cancer
5. Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant awarded to Johns Hopkins Early Career investigator
6. ORAL COTI-2 IS EFFECTIVE IN AN ANIMAL MODEL OF HUMAN PANCREATIC CANCER
7. Blood-flow metabolism mismatch predicts pancreatic tumor aggressiveness
8. Newly discovered epidermal growth factor receptor active in human pancreatic cancers
9. Device protects transplanted pancreatic cells from the immune system
10. Compendium of pancreatic cancer biomarkers established as strategic approach to early-detection
11. HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... 2014(BRONX, NY)Researchers at Albert Einstein College of Medicine ... The Michael J. Fox Foundation for Parkinson,s Research to ... Parkinson,s disease. This drug discovery project will test chemical ... of developing a drug that acts on an underlying ... for Parkinson,s help many people manage their symptoms, we ...
(Date:7/24/2014)... which have similar counterparts in humans, affect the connections ... signals into the hippocampus, an area of the brain ... the creation of memories. The results of the study ... , Brain function depends on the active communication between ... are woven together into a dense network where they ...
(Date:7/24/2014)... is a hotspot of biodiversity and one of the ... toads) in the world. However, current levels of diversity ... has been an increase in the description of new ... of molecular techniques and availability of samples for DNA ... samples for molecular and morphological analysis, researchers from the ...
Breaking Biology News(10 mins):Albert Einstein College of Medicine receives grant from the Michael J. Fox Foundation to fund drug discovery project targeting Parkinson's 2Albert Einstein College of Medicine receives grant from the Michael J. Fox Foundation to fund drug discovery project targeting Parkinson's 3A protein couple controls flow of information into the brain's memory center 2A protein couple controls flow of information into the brain's memory center 3A protein couple controls flow of information into the brain's memory center 4A tiny new species of frog from Brazil with a heroic name 2
... members at the University of South Florida in Tampa have ... of Science (AAAS). Election as an AAAS Fellow is an ... This year 388 members have been awarded this honor by ... advance science or its applications. With six Fellows, ...
... so do portion size and the amount of food actually ... people are to this plate-size bias? New research by the ... children respond differently to environmental cues, such as plate size, ... breakfast behaviors of kids, ages 6 to 10, in a ...
... a variety of methods to spread their seeds, including gravity, ... of the mushrooms, whose spores also need to be strewn ... have long thought that the spores produced by a mushroom,s ... problem with that notion, said Emilie Dressaire, a professor of ...
Cached Biology News:AAAS and the University of South Florida announce 2013 Fellows 2AAAS and the University of South Florida announce 2013 Fellows 3AAAS and the University of South Florida announce 2013 Fellows 4AAAS and the University of South Florida announce 2013 Fellows 5Extrovert and introvert children are not equally influenced by plate size 2The mushrooms, my friend, are blowing in the wind... 2
(Date:7/24/2014)... July 24, 2014   Cypher Genomics, Inc., ... appointment of Adam Simpson as president ... rapid and comprehensive annotation and interpretation of individual ... "Cypher,s technology has the potential to ... enhancing diagnostic accuracy, optimizing therapeutic approaches and reducing ...
(Date:7/23/2014)... , July 24, 2014 Lyfebulb, the ... Inc. (OTCQX and NASDAQ OMX First North Premier, ... "the Company"), announced a collaboration to increase awareness ... night at an event attended by more than ... Lyfebulb is a health and wellness company dedicated ...
(Date:7/23/2014)... Heroic worldwide conservation efforts have made great strides in ... in China, there are over 65 giant panda reserves ... But despite these efforts, just 1596 pandas remain in ... and zoos hope to save the panda by improving ... to the wild. Just how are these high-profile programs ...
(Date:7/23/2014)... 2014 /PRNewswire-iReach/ -- Think Drinks are a neuroscience-backed drink ... term. They are the first functional focus beverage to ... an alternative to the temporary fix associated with energy ... July 29, 2014, with hopes to raise $50,000 over ... - http://photos.prnewswire.com/prnh/20140723/129697 Think Drinks ...
Breaking Biology Technology:Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 2Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 3Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 2Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 3Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 4Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 5truBrain Neuroscientists To Launch More Effective, Healthier Alternative To Energy Drinks On Indiegogo 2
... June 14 aTyr Pharma, Inc. today announced ... joined the company as its Senior Vice President of ... help to advance aTyr Pharma,s portfolio of resectin-based therapeutics. ... derived from aminoacyl tRNA synthetases, and have activities relevant ...
... June 14 Data presented at the ... , highlights the impact of febrile neutropenia (FN) on ... NHL study showed that unplanned hospitalisations, delays in chemotherapy ... dose intensity (RDI) of chemotherapy were more frequent in ...
... ... on centralizing information to meet researchers, needs. , ... (PRWEB) -- STEMCELL Technologies Inc has just launched its next ... to meet researchers, needs., , ,The site has been completely redesigned to provide specialized sections ...
Cached Biology Technology:aTyr Pharma Appoints Catharine E. Johnson As Senior Vice President of Business Development 2aTyr Pharma Appoints Catharine E. Johnson As Senior Vice President of Business Development 3New Data Confirms the Negative Impact of Febrile Neutropenia in Patients With Non-Hodgkin Lymphoma Receiving R-CHOP Chemotherapy 2New Data Confirms the Negative Impact of Febrile Neutropenia in Patients With Non-Hodgkin Lymphoma Receiving R-CHOP Chemotherapy 3New Data Confirms the Negative Impact of Febrile Neutropenia in Patients With Non-Hodgkin Lymphoma Receiving R-CHOP Chemotherapy 4New Data Confirms the Negative Impact of Febrile Neutropenia in Patients With Non-Hodgkin Lymphoma Receiving R-CHOP Chemotherapy 5New Data Confirms the Negative Impact of Febrile Neutropenia in Patients With Non-Hodgkin Lymphoma Receiving R-CHOP Chemotherapy 6New Data Confirms the Negative Impact of Febrile Neutropenia in Patients With Non-Hodgkin Lymphoma Receiving R-CHOP Chemotherapy 7New Data Confirms the Negative Impact of Febrile Neutropenia in Patients With Non-Hodgkin Lymphoma Receiving R-CHOP Chemotherapy 8New Data Confirms the Negative Impact of Febrile Neutropenia in Patients With Non-Hodgkin Lymphoma Receiving R-CHOP Chemotherapy 9STEMCELL Technologies Inc Launches New Website 2
... Anti-Natural Killer Cell Receptor-P1, clone ... Hybridoma produced by ... BALB/c mice immunized (BALB/c X ... cells and mouse myeloma cellline. ...
... monoclonal [YPF19] to Yersinia pestis ... Yersinia pestis . Immunogen: ... Yersinia pestis vaccine strain EV76. ... recognises Y.pestis F1 capsular antigen. There ...
Rabbit polyclonal to ZFP200 ( Abpromise for all tested applications). Antigen: Synthetic peptide: CGKSFNHKTNLNKHER (Human) Entrez Gene ID: 7752 Swiss Protein ID: P98182...
Anti-human C3a/C3a des-Arg (neo-epitope), Clone 2991, Monoclonal Antibody...
Biology Products: