Navigation Links
PNNL's Richard Smith named 2010 Scientist of the Year
Date:11/1/2010

RICHLAND, Wash. -- Parkinson's disease, cancer and biofuels production are just a few problems that biochemist Dick Smith has helped untangle in his long career of technological innovation and scientific insight. Now, R&D Magazine has honored Smith as 2010 Scientist of the Year for his many significant contributions to science.

Called "creative," "innovative" and "adventurous" by his colleagues, Smith is currently the director of proteomics at the Department of Energy's Pacific Northwest National Laboratory. Since the 1980s, Smith has pushed technological advancements in this field, bringing analytical chemistry techniques into the domain of microbiologists and medical researchers. He is the first DOE scientist to earn this honor.

Smith is one of the most-published scientists in the field of proteomics (pro'-tee-oh'-mics), which seeks to understand biology by the complement of proteins at work within organisms, tissues or cells. Since the Human Genome Project developed a blueprint of all human genes in our chromosomes earlier this century, proteomics researchers have pushed to understand how the blueprint creates life. Genes are the blueprints of proteins, which are the cogs, gears and levers in complex, intricate biological machines.

Proteins often go wrong in disease or infection, and finding those requires sifting through thousands of other proteins. Many problem proteins don't have names or are too rare to find easily.

In the last few years, Smith has led work that trimmed analytical steps from hours to minutes. The increase in speed has enabled many samples to be processed faster in high-throughput experiments. Smith led other advances in sensitivity and accuracy that have improved the ability to find rare proteins, bringing proteomics technology to the doorstep of clinical researchers.

Smith and collaborators have applied the technology to liver disease and cancer in the hopes of finding rare markers of disease in blood, making diagnosis or treatment safer and faster. In 2007, Scientific American magazine listed Smith and his collaborator Desmond Smith as one of the top 50 researchers for work to understand the origins of Parkinson's disease by mapping where proteins amass in diseased mouse brains.

Among other work, Smith and colleagues have looked at how bacteria and viruses might cause illness. They've learned breast cancer leaves traces behind in the blood that doctors might exploit someday. Smith has led studies for DOE into possible roles for microbes in making biofuels. In other DOE studies, he's examined how large environmental communities of microbes function in our ecosystem and affect our environment. An intimate understanding of how microbes work will let researchers employ them to trap radioactive contaminants or greenhouse gases.

In accepting the award, Smith joins the ranks of such preeminent scientists as Eric Lander, director of Massachusetts Institute of Technology's Broad Institute and one of the leaders of the Human Genome Project; Susan Solomon, a NOAA chemist who connected CFCs to the ozone hole; and George M. Whitesides, a Harvard University chemist and winner of the 2009 Dreyfus Prize in the Chemical Sciences for new materials that have significantly advanced the field of chemistry.

"I'm surprised and pleased at the honor, and happy to be in such great company," said Smith. "And I'm especially grateful to the incredibly talented team of researchers at the lab who I have been able to work with."

Much of his group's cutting-edge technology -- including mass spectrometers beefed up with ion funnels and electrospray ionization -- is housed at EMSL, DOE's Environmental Molecular Sciences Laboratory on the PNNL campus. A number of the developments have been licensed to private companies. R&D Magazine will present the award to Smith at a ceremony in Orlando, Fla. on Nov. 11.


'/>"/>

Contact: Mary Beckman
mary.beckman@pnl.gov
509-375-3688
DOE/Pacific Northwest National Laboratory
Source:Eurekalert  

Related biology news :

1. Brupbacher prize to Nubia Munoz and Sir Richard Peto
2. Jonathan Berg, M.D., Ph.D. awarded Richard King Trainee Award for Best in Genetics in Medicine
3. American Society for Microbiology honors Richard W. Castenholz
4. Dr. Richard Feinman to speak on the science of diabetes and diet on Oct. 2
5. Marwan Khaled Tayeh, Ph.D., is awarded the 2010 Richard King Trainee Award
6. More Than 100 Global and U.S. Municipal Leaders Join Mayor Daley, Business, Civic, Academic and Foundation Leaders at 2010 Richard J. Daley Global Cities Forum
7. Dean of the UM College of Engineering to receive 2010 IEEE Richard M. Emberson Award
8. Smithsonian perspective: Biodiversity in a warmer world
9. Smithsonian puts tropical Eastern-Pacific shore fishes online
10. Smithsonian puts tropical eastern Pacific shore fishes online
11. New movement models tested at the Smithsonian in Panama
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
PNNL's Richard Smith named 2010 Scientist of the Year
(Date:5/16/2017)... N.J. , May 16, 2017  Veratad Technologies, ... provider of online age and identity verification solutions, announced ... K(NO)W Identity Conference 2017, May 15 thru May 17, ... Regan Building and International Trade Center. ... the globe and in today,s quickly evolving digital world, ...
(Date:5/6/2017)... May 5, 2017 RAM Group ... a new breakthrough in biometric authentication based on ... mechanical properties to perform biometric authentication. These new sensors ... material created by Ram Group and its partners. This ... transportation, supply chains and security. Ram Group is ...
(Date:4/19/2017)... The global military biometrics market ... by the presence of several large global players. The ... major players - 3M Cogent, NEC Corporation, M2SYS Technology, ... 61% of the global military biometric market in 2016. ... military biometrics market boast global presence, which has catapulted ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ComplianceOnline’s Medical ... place on 7th and 8th June 2018 in San Francisco, CA. The Summit brings ... well as several distinguished CEOs, board directors and government officials from around the world ...
(Date:10/11/2017)... ROTTERDAM, the Netherlands and LAGUNA HILLS, ... that The Institute of Cancer Research, London ... will use MMprofiler™ with SKY92, SkylineDx,s prognostic tool to risk-stratify ... high-risk trial known as MUK nine . The University ... this trial, which is partly funded by Myeloma UK, and ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... granted orphan drug designation to SBT-100, its novel anti-STAT3 (Signal Transducer and Activator ... osteosarcoma. SBT-100 is able to cross the cell membrane and bind intracellular STAT3 ...
(Date:10/10/2017)... ... October 10, 2017 , ... For the second time in ... STEM Mentoring Award. Representatives of the FirstHand program travelled to Washington, D.C. Tuesday, ... , US2020’s mission is to change the trajectory of STEM education in America ...
Breaking Biology Technology: