Navigation Links
PNNL's Richard Smith named 2010 Scientist of the Year
Date:11/1/2010

RICHLAND, Wash. -- Parkinson's disease, cancer and biofuels production are just a few problems that biochemist Dick Smith has helped untangle in his long career of technological innovation and scientific insight. Now, R&D Magazine has honored Smith as 2010 Scientist of the Year for his many significant contributions to science.

Called "creative," "innovative" and "adventurous" by his colleagues, Smith is currently the director of proteomics at the Department of Energy's Pacific Northwest National Laboratory. Since the 1980s, Smith has pushed technological advancements in this field, bringing analytical chemistry techniques into the domain of microbiologists and medical researchers. He is the first DOE scientist to earn this honor.

Smith is one of the most-published scientists in the field of proteomics (pro'-tee-oh'-mics), which seeks to understand biology by the complement of proteins at work within organisms, tissues or cells. Since the Human Genome Project developed a blueprint of all human genes in our chromosomes earlier this century, proteomics researchers have pushed to understand how the blueprint creates life. Genes are the blueprints of proteins, which are the cogs, gears and levers in complex, intricate biological machines.

Proteins often go wrong in disease or infection, and finding those requires sifting through thousands of other proteins. Many problem proteins don't have names or are too rare to find easily.

In the last few years, Smith has led work that trimmed analytical steps from hours to minutes. The increase in speed has enabled many samples to be processed faster in high-throughput experiments. Smith led other advances in sensitivity and accuracy that have improved the ability to find rare proteins, bringing proteomics technology to the doorstep of clinical researchers.

Smith and collaborators have applied the technology to liver disease and cancer in the hopes of finding rare markers of disease in blood, making diagnosis or treatment safer and faster. In 2007, Scientific American magazine listed Smith and his collaborator Desmond Smith as one of the top 50 researchers for work to understand the origins of Parkinson's disease by mapping where proteins amass in diseased mouse brains.

Among other work, Smith and colleagues have looked at how bacteria and viruses might cause illness. They've learned breast cancer leaves traces behind in the blood that doctors might exploit someday. Smith has led studies for DOE into possible roles for microbes in making biofuels. In other DOE studies, he's examined how large environmental communities of microbes function in our ecosystem and affect our environment. An intimate understanding of how microbes work will let researchers employ them to trap radioactive contaminants or greenhouse gases.

In accepting the award, Smith joins the ranks of such preeminent scientists as Eric Lander, director of Massachusetts Institute of Technology's Broad Institute and one of the leaders of the Human Genome Project; Susan Solomon, a NOAA chemist who connected CFCs to the ozone hole; and George M. Whitesides, a Harvard University chemist and winner of the 2009 Dreyfus Prize in the Chemical Sciences for new materials that have significantly advanced the field of chemistry.

"I'm surprised and pleased at the honor, and happy to be in such great company," said Smith. "And I'm especially grateful to the incredibly talented team of researchers at the lab who I have been able to work with."

Much of his group's cutting-edge technology -- including mass spectrometers beefed up with ion funnels and electrospray ionization -- is housed at EMSL, DOE's Environmental Molecular Sciences Laboratory on the PNNL campus. A number of the developments have been licensed to private companies. R&D Magazine will present the award to Smith at a ceremony in Orlando, Fla. on Nov. 11.


'/>"/>

Contact: Mary Beckman
mary.beckman@pnl.gov
509-375-3688
DOE/Pacific Northwest National Laboratory
Source:Eurekalert  

Related biology news :

1. Brupbacher prize to Nubia Munoz and Sir Richard Peto
2. Jonathan Berg, M.D., Ph.D. awarded Richard King Trainee Award for Best in Genetics in Medicine
3. American Society for Microbiology honors Richard W. Castenholz
4. Dr. Richard Feinman to speak on the science of diabetes and diet on Oct. 2
5. Marwan Khaled Tayeh, Ph.D., is awarded the 2010 Richard King Trainee Award
6. More Than 100 Global and U.S. Municipal Leaders Join Mayor Daley, Business, Civic, Academic and Foundation Leaders at 2010 Richard J. Daley Global Cities Forum
7. Dean of the UM College of Engineering to receive 2010 IEEE Richard M. Emberson Award
8. Smithsonian perspective: Biodiversity in a warmer world
9. Smithsonian puts tropical Eastern-Pacific shore fishes online
10. Smithsonian puts tropical eastern Pacific shore fishes online
11. New movement models tested at the Smithsonian in Panama
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
PNNL's Richard Smith named 2010 Scientist of the Year
(Date:1/3/2017)... Onitor, provider of digital health technology for ... innovative biometric data-driven program designed to aid weight loss ... 2017 Consumer Electronics Show (CES) in Las ... the World Health Organization (WHO), have identified lifestyle risks ... are overweight or obese. WHO also states that more ...
(Date:12/19/2016)... TORONTO , 19 de diciembre de 2016  Mosaic ... permitirá el desarrollo acelerado de MSC-1, un anticuerpo humanizado que se ... tumor en 2017, con múltiples sitios previstos a lo largo de ... ... el factor inhibidor de leucemia (LIF), una citoquina pleiotrópica que se ...
(Date:12/15/2016)... FREMONT, Calif. , Dec. 15, 2016   ... a publicly held genomics technology company, announced today that ... the Listing Qualifications Department of The Nasdaq Stock Market ... the closing bid price of WaferGen,s common stock had ... days.  Accordingly, WaferGen has regained compliance with Listing Rule ...
Breaking Biology News(10 mins):
(Date:1/19/2017)... 2017  ArmaGen, Inc., today announced that it ... chief executive officer, as well as a member ... ArmaGen more than 17 years of executive management ... biotherapeutics and pharmaceuticals. "Mathias is ... and skillset necessary to lead ArmaGen to its ...
(Date:1/19/2017)... ... , ... FireflySci Inc. is a go-getter type of company that continues to ... two main factors. The first is the amazing customer service that the FireflySci ... all around the world. , 2016 was a tremendous sales year for FFS and ...
(Date:1/19/2017)... 18, 2017 Acupath Laboratories, Inc., a leading ... of an Executive Committee that will guide the company,s ... John Cucci , a 15-year veteran of the ... Business Development to Chief Sales Officer .  Prior ... in senior sales leadership roles at several leading lab ...
(Date:1/18/2017)... --  Boston Biomedical , an industry leader in the ... pathways, will feature data from two clinical studies for ... Gastrointestinal Cancers Symposium, held from January 19-21, in ... is an orally-administered investigational agent designed to inhibit cancer ... cells (CSCs) possess the property of stemness – the ...
Breaking Biology Technology: