Navigation Links
PD map: Putting together the pieces of the Parkinson's puzzle
Date:10/23/2013

Parkinson's disease continues to puzzle physicians and biologists alike - even though it is well-established that symptoms like muscle tremors, rigidity, and, during the final stages, immobility can all be traced back to the death of a certain type of brain cell called a dopaminergic neuron. The underlying cause of this cellular death is a complex web of interrelated genetic molecular processes as well as external factors, most of the details of which are well-known. But how the various factors correlate and influence each other continues to elude the scientific community. Now for the first time ever, researchers at the Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg have published an interactive picture containing the current knowledge about the underlying genetic and molecular causes of Parkinson's disease. This "Parkinson's disease map," or "PD Map" for short has been published in the scientific journal Molecular Neurobiology. It will facilitate the systematic study of PD through a newly gained clarity of the existing knowledge about the disease (DOI 10.1007/s12035-013-8489-4).

"Indeed, biomedical research continuously gives us many new insights about Parkinson's." says Dr. Marek Ostaszewski, coordinator of the LCSB PD Map project. "Each year, thousands of new scientific publications appear on the subject - yet no single individual could possibly hope to keep a detailed track of this flood of information." All of this knowledge has to be sorted, meaningfully correlated, and continually refined to ultimately benefit patients. Ever since the Centre's founding four years ago, the LCSB scientists have made it a point to develop this disease overview and put it in a useful format of an interactive map available to both researchers and clinicians. In developing the map, the LCSB scientists worked closely with their colleagues at the Systems Biology Institute (SBI) in Tokyo, Japan. The SBI researchers already creat
'/>"/>

Contact: Sabine Mosch
sabine.mosch@uni.lu
352-466-644-6423
University of Luxembourg
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Putting the spring back in broken hearts
2. Putting flesh on the bones of ancient fish
3. Kirk, Spock together: Putting emotion, logic into computational words
4. GSA Today: Putting time in its place
5. Putting plants online: 4 leading botanical gardens to create first online catalog of all plants
6. Institut Pasteur Korea -- DNDi come together for the fight against neglected diseases
7. Telecoupling pulls pieces of sustainability puzzle together
8. GSA, the Paleontological Society, and SEPM in STEPPE together
9. Were in this together: A pathbreaking investigation into the evolution of cooperative behavior
10. Recent studies bring fossils and genes together to piece together evolutionary history
11. Learning from each other -- growing together
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
PD map: Putting together the pieces of the Parkinson's puzzle
(Date:4/23/2014)... coal for domestic heating may contribute to early fetal ... The Saban Research Institute of Children,s Hospital Los Angeles ... the world. , In a paper published today in ... report ,"alarmingly strong statistical correlations" between seasonal ambient air ... , UB has one of the highest levels of ...
(Date:4/23/2014)... in French and Spanish . ... 2014Today, the CEC released its Conservation Assessment for the ... Conservation, which identifies 29 priority conservation areas in a ... different protected areas in the states of Texas, Coahuila, ... and semi-arid habitats inhabited by rare and endangered plants ...
(Date:4/23/2014)... accurate group decision increases with the abundance of brains ... a variety of factors as often happens in ... smaller groups actually tend to make more accurate decisions ... certain pieces of information. , The findings present a ... or the "wisdom of crowds," wherein individual observations ...
Breaking Biology News(10 mins):Pollutants from coal-burning stoves strongly associated with miscarriages in Mongolia 2Conservation priorities released for several protected areas along US-Mexico border 2Conservation priorities released for several protected areas along US-Mexico border 3Too many chefs: Smaller groups exhibit more accurate decision-making 2Too many chefs: Smaller groups exhibit more accurate decision-making 3
... mother,s diet during gestation and lactation were found to be ... those not exposed to the chemical, researchers at the University ... is a chemical most commonly found in the lining of ... many hard plastic bottles, including baby bottles, but many companies ...
... Conn.Like organisms, cities need energy, water, and nutrients, and ... ways that are viable and sustainable over the long ... for looking systematically at the resources that flow into ... from themto understand the environmental impacts of cities and ...
... 2013 UC Irvine neuroscientists have developed a way ... a novel opportunity to treat the most severe manifestations ... of temporal lobe epilepsy, Ivan Soltesz, Chancellor,s Professor and ... EEG-based computer system that activates hair-thin optical strands implanted ...
Cached Biology News:Female mice exposed to BPA by mothers show unexpected characteristics 2Female mice exposed to BPA by mothers show unexpected characteristics 3Urban metabolism for the urban century 2
(Date:1/15/2014)... 2014  Bill Jacobs Automotive, a group of car dealerships headquartered ... the Heartland Blood Center and offering free oil change coupons ... place Saturday, Jan. 18 at the Bill Jacobs Cadillac and ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46637 )  The Bill Jacobs ...
(Date:1/15/2014)... 2014   Niagara Thermal Products is proud to ... Technologies LLC ("B3") as the critical thermal component supplier ... the Army Corps of Engineers.  B3 has developed the ... contaminants and destroys VOCs and other chemical pollutants, allergens ...
(Date:1/15/2014)... Village, Calif. (PRWEB) January 15, 2014 ... treatment and management through the genomic analysis of tumor ... offer Therapy Finder™, a web-based cancer decision support application ... reporting option with Cynvenio’s ClearID™ genomic test, Therapy Finder ...
(Date:1/15/2014)... ­ RedBrick Health , a fast-growing leader in ... that EmblemHealth , the New York ... providing the RedBrick Compass health assessment, combined with the ... its members. EmblemHealth is among the first health plans ...
Breaking Biology Technology:Join the Bill Jacobs Auto blood drive and receive a free oil change 2Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 3EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3
... In the quest to exploit unique properties at ... have developed a novel technique for creating uniform ... and students in the Department of Physics and ... methods from holographic lithography to demonstrate a new ...
... Pharmaceuticals, Inc. (NASDAQ: IDIX ), announced today that ... Stanley Global Healthcare Conference on September 13 at 8:35 a.m. ... the Bank of America Merrill Lynch Global Healthcare Conference on ... of America Merrill Lynch Financial Centre, London.   ...
... Cellectis (Alternext: ALCLS), the French genome engineering specialist, will present at ... September 20, 2011, and at the MidCap Event in Paris on ... will present the activities and the development strategy of the Cellectis ... Hyatt New York hotel on Tuesday, September 20, 2011 at 11:30 ...
Cached Biology Technology:Stevens researchers pioneer novel technique to make plasmonic nanogap arrays 2Stevens researchers pioneer novel technique to make plasmonic nanogap arrays 3
RABBIT ANTI ISOCITRATE DEHYDROGENASE...
... two highly efficient methods of identifying recombinant ... By using the large-scale screen method in ... is to transfer partial colonies of E. ... into the solutions provided by the kits ...
Recombinant Rat Leptin, CF...
Rat whole blood (Sprague-Dawley, averaging 7-8 weeks of age, either sex) is collected at the time of slaughter and refrigerated within 6 hours, and processed and frozen within 24 hours. The serum is ...
Biology Products: