Navigation Links
PBS-Bio works with 3 new firms to accelerate cancer drug development
Date:10/20/2010

ds of drug discovery and development. Pharmaceutical companies are now seeing the value of the PBS-Bio dynamic technology to help bring more new cancer drugs to market faster and cheaper."

In each case, connections to PBS-Bio were made through scientific networks involving the Translational Genomics Research Institute (TGen), a Phoenix-based biomedical research facility.

And in each case, PBS-Bio is providing drug companies with unique real-time looks at how new therapeutics actually work over time within cellular pathways the so-called mechanisms of action.

ENDECE

Rather than focusing on a single target or mutation, ENDECE's approach is to identify key molecular switches that prevent tumors from growing out of control.

"We previously identified a primary mechanism of action for how NDC-1308 kills tumor cells. However, the PBS-Bio technology will validate that mechanism and enable us to observe, in real time, the temporal order of changes for components of the pathways that control cancer cell growth," said James Yarger, President and CEO of ENDECE. "In addition, we may obtain data showing the impact, both positive and negative, of NDC-1308 on other cellular pathways. With current technology, we have not been able to identify the temporal order of events."

By working with PBS-Bio, Yarger said, his company also hopes to determine which cancer patients might be the best candidates for the drug and gain an understanding of what current cancer drugs, if any, would be appropriate candidates for combination drug therapies.

"Our bodies fight cancer cells every day, and in general our bodies do it very, very well. However, the appearance of cancerous tumors signifies uncontrolled cancer cell growth and proliferation. When the body's control over some of these pathways are lost, the cancer cells can grow out of control," Yarger said. "ENDECE's focus is on novel therapies that enhance the body's na
'/>"/>

Contact: Dr. Edward Smith
edsmith@pbs-bio.com
602-418-9300
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Report: Discovery networks hostage-taking a rare terror event
2. University of Miami to host prestigious National Geographic Young Explorers Workshop, Sept. 25
3. IU receives $9.2 million from NSF to expand global networks and research
4. SRNL works to decrease hazards from mold in water damaged homes
5. Wildlife, virus zoonoses focus of workshop
6. Plastic antibody works in first tests in living animals
7. Moral issues raised by synthetic biology subject of Hastings Center workshop
8. AAPS presents therapeutic protein drug interactions workshop
9. Entertainment Studios Networks Names Janice Arouh President, Domestic Distribution and Marketing
10. Modeling reef ecosystems focus of workshop
11. Forest service co-hosts annual air pollution workshop
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... uses reversible epigenetic processes to regulate its genes, and ... a picture of the genome regulation taking place in ... Genome Biology and illustrates how the truffle ... genes,. The authors say this may shed light on ... Black truffles (Tuber melanosporum), also known as Prigord truffles, ...
(Date:7/30/2014)... and tended her eggs until they hatched 4.5 years ... in the open-access journal PLOS ONE by ... colleagues. , Octopuses typically have a single reproductive period ... care of their fertilized eggs until they hatch. Shallow-water ... 3 months, but little is known about the brooding ...
(Date:7/30/2014)... Scientists studying the potential effects of climate change ... focusing on the wrong factors, according to a ... Wildlife Conservation Society, University of Queensland, and other ... conservation science is missing the point when it ... majority of climate change scientists focus on the ...
Breaking Biology News(10 mins):How black truffles deal with the jumpers in their genome 2Deep-sea octopus has longest-known egg-brooding period 2Conservation scientists asking wrong questions on climate change impacts on wildlife 2
... DC May 18, 2010 -- The American Society for ... , a new open access online journal designed to make ... is on rapid publication of cutting-edge research spanning the entire ... "The microbial world is a highly interconnected one in which ...
... provide visible and infrared imagery of Iceland,s Eyjafjallajokull Volcano ... plume being pulled in a northeasterly direction over the ... pushed to the northeast from a low pressure area ... or MODIS instrument that flies aboard Terra captured an ...
... Greenland is situated in the Atlantic Ocean to the ... coast formed by moving glaciers, and a dense icecap up ... down the land beneath and lowering its elevation. Now, scientists ... so quickly that the land underneath is rising at an ...
Cached Biology News:ASM launches new open access journal 2Greenland rapidly rising as ice melt continues 2
(Date:7/31/2014)... (PRWEB) July 31, 2014 The global ... 8,020.1 million by 2020, according to a new study ... medicine and theranostics, and the subsequent introduction of advanced ... driving market growth over the next six years. Moreover, ... diseases such as cancer, coupled with disease triggering lifestyle ...
(Date:7/31/2014)... Wash. , July 31, 2014   BioLife ... leading developer, manufacturer and marketer of proprietary clinical grade ... media and precision thermal shipping products for ... second quarter 2014 financial results will be released on ... host a conference call and live webcast at 4:30 ...
(Date:7/31/2014)... MA (PRWEB) July 31, 2014 Boston’s ... finds itself flush with innovative adult stem cell biotechnologies. ... patents and has three additional patent applications currently ... , The patented inventions address two of the most ... regenerative medicine. Adult stem cells are difficult to ...
(Date:7/30/2014)... TARRYTOWN, N.Y. and PARIS ... REGN) and Sanofi (EURONEXT: SAN and NYSE: SNY) today ... Food and Drug Administration (FDA) rare pediatric disease priority ... (BLA) submission for alirocumab.  The priority review voucher entitles ... which provides for an expedited 6-month review from the ...
Breaking Biology Technology:Molecular Diagnostics Market - Global Industry Size, Share, Trends, Analysis, Players, Opportunity, Outlook and Forecast From 2014 to 2020 2Molecular Diagnostics Market - Global Industry Size, Share, Trends, Analysis, Players, Opportunity, Outlook and Forecast From 2014 to 2020 3Molecular Diagnostics Market - Global Industry Size, Share, Trends, Analysis, Players, Opportunity, Outlook and Forecast From 2014 to 2020 4Molecular Diagnostics Market - Global Industry Size, Share, Trends, Analysis, Players, Opportunity, Outlook and Forecast From 2014 to 2020 5BioLife Solutions to Report Financial Results for Second Quarter 2014 and Provide Business Update on August 7, 2014 2The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 2The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 4Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 5Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 6
... UPPSALA, Sweden, October 5 , ... - At One Sixth the Price of QuanTyper(TM) Without Loss of ... Rapidly Penetrate the Market , AlphaHelix (Ticker: ... AmpXpress(TM) - to meet demands for lower,instrument prices. This was made ...
... Inc. (Nasdaq: ONTY ) (TSX: ONY) today announced ... Officer of ZymoGenetics, Inc. (Nasdaq: ZGEN), to its board ... to our board of directors and look forward to ... experience in drug development, research and operations will be ...
... , BASKING RIDGE, N.J., Oct. 5 Regado Biosciences, ... aptamers with active control agents, announced today that David ... be presenting at the Japan Biopharma Conference 2009 at ... presentation is scheduled for 2:40pm (GMT +9:00) on October ...
Cached Biology Technology:AlphaHelix Presents AmpXpress(TM) at the BIOTECHNICA Show 2Oncothyreon announces appointment of Douglas E. Williams, Ph.D., to board of directors 2Regado Biosciences To Present at the 2009 Japan Biopharma Partnering Conference on October 6, 2009 2
... Microarrays designed for pathway studies, ... protein (PTB) Studies built on the ... synthesis platform. These microarrays are available ... Peptide Microarray Service. Custom ...
... normal Mega Western Protein Array was developed ... Western Protein Arrays are manufactured using high ... sources. A protein sample from each of ... a Protein molecular weight marker on a ...
... Superior Protein Detection and Quantitation Over ... Proteomic Imaging System is a highly sensitive ... life science research applications. ProXPRESS 2D provides ... dyes in the UV and VIS spectrum ...
... 7 lanes of total ... brain tissue including: precentral ... lobe, temporal lobe, parietal ... cerebellum. Patent/trademark/license (electronic): Manufactured ...
Biology Products: