Navigation Links
PBS-Bio works with 3 new firms to accelerate cancer drug development
Date:10/20/2010

MESA, Ariz. Oct. 20, 2010 In an industry that faces increasing challenges in delivering new drugs to patients, Predictive Biomarker Sciences (PBS-Bio) today announced three new contracts aimed at bringing new medicines to the marketplace.

PBS-Bio said it is helping more companies develop therapies against a variety of cancers. Most new cancer drugs fail in late-stage studies, and it can take as much as $1 billion and more than a decade to bring the drugs to market.

To jump-start drug development, PBS-Bio's analysis helps pharmaceutical companies better understand how their drugs work, and identifies biomarkers that can help predict which patients will respond to treatment.

PBS-Bio's three new pharmaceutical collaborators are:

  • ENDECE, a Mequon, Wis., company that discovered and is developing a family of anti-cancer compounds, including their lead compound NDC-1308, which target molecular "bioswitches" that control metabolic pathways impacting cancer cell growth.

  • Revalesio Corporation, a Tacoma, Wash., group developing novel therapeutic candidates containing "charged-stabilized nanostructures" to prevent inflammatory mediated diseases without inhibiting normal cellular functions.

  • Unibioscreen, a Brussels, Belgium, firm that is developing a promising anti-cancer drug called UNBS1450 currently in European clinical trials.

These three small pharmaceutical companies are in addition to four collaborations in progress between PBS-Bio and four large pharma groups, said Dr. Edward Smith, co-founder and CEO of PBS-Bio, which is a privately held, Mesa-based for-profit corporation.

"We feel that we have reached critical momentum for the growth of PBS-Bio," said Dr. Smith. "The pharmaceutical industry is failing in their efforts to bring new cancer drugs to patients with only two drugs approved in 2009, and only two so far this year. The problems are empty pipelines, and outdated metho
'/>"/>

Contact: Dr. Edward Smith
edsmith@pbs-bio.com
602-418-9300
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Report: Discovery networks hostage-taking a rare terror event
2. University of Miami to host prestigious National Geographic Young Explorers Workshop, Sept. 25
3. IU receives $9.2 million from NSF to expand global networks and research
4. SRNL works to decrease hazards from mold in water damaged homes
5. Wildlife, virus zoonoses focus of workshop
6. Plastic antibody works in first tests in living animals
7. Moral issues raised by synthetic biology subject of Hastings Center workshop
8. AAPS presents therapeutic protein drug interactions workshop
9. Entertainment Studios Networks Names Janice Arouh President, Domestic Distribution and Marketing
10. Modeling reef ecosystems focus of workshop
11. Forest service co-hosts annual air pollution workshop
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... standards process, will be available soon and will improve ... in the OnlineFirst version of Nutrition in Clinical ... the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.), ... misconnection that can be harmful and even fatal to ... medical devices, components, and accessories to deliver fluids or ...
(Date:8/20/2014)... a John and Rebecca Moores Professor of Biology and Biochemistry ... in the International Society for the Study of the Origin ... members two from the U.S., one from France and ... are elected every three years, and 36 have been named ... 20 countries, the ISSOL includes researchers from disciplines as varied ...
(Date:8/20/2014)... the University of Tbingen, Arizona State University, the Wellcome ... Health Institute (Swiss TPH) isolated Mycobacterium pinnipedii ... 1000 years old. The pathogen is a relative of ... causes disease in humans today. These researchers assume that ... coast. "The link to sea lions was unexpected" comments ...
Breaking Biology News(10 mins):New feeding tube connectors will improve patient safety 2UH professor named fellow by International Astrobiology Society 2
... the battle of the sexes, African electric fish couples ... also engage in a sort of dueling "electric duet." ... and behavioral displays in breeding and nonbreeding Brienomyrus brachyistius, ... electric fields from a batterylike organ in their tails ...
... brain consists of billions of nerve cells enabling to ... experience, touch, smell or fear, millions of neurons in ... each other by chemical and electrical impulses to compute ... regions. With 20,000 - 25,000 genes in our genome, ...
... Board: NRGX) today announced the publication in the June 23 ... the first ever gene therapy trial for Parkinson’s disease and ... own brain cells for any adult neurodegenerative disease. , ... with advanced Parkinson’s disease demonstrated both a lack of adverse ...
Cached Biology News:Turn-ons and turn-offs for neurons 2Gene therapy study shows safety and statistically significant improvement in Parkinson's disease 2Gene therapy study shows safety and statistically significant improvement in Parkinson's disease 3Gene therapy study shows safety and statistically significant improvement in Parkinson's disease 4
(Date:8/21/2014)... (PRWEB) August 21, 2014 Ontotext ... today by Ontotext . Now the same ... analysis of structured and unstructured data is available to ... cost of enterprise technology. Organizations that do not have ... data management can use S4 since there is no ...
(Date:8/21/2014)... 2014 On Wednesday of last week RENU ... Redox Signaling molecules, became available for purchase in Australia and ... way that RENU 28 works is, if you think about ... the rate of cellular renewal within your body. If you ... that rate of cellular renewal. What RENU 28 does is ...
(Date:8/20/2014)... American Indians largely were wiped out by diseases such ... to the New World by European explorers., One report ... in the Americas shortly before Europeans arrived, and roughly ... But new research led by anthropological geneticists Anne Stone ... University of Tubingen in Germany indicates the diagnosis of ...
(Date:8/20/2014)... 20, 2014 High performance computing ... the most complete climate and Earth system model ... change issues. , Eight national laboratories, including ... National Center for Atmospheric Research, four academic institutions ... Other participating national laboratories include Argonne, Brookhaven, Lawrence ...
Breaking Biology Technology:Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 2Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 3Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 4RENU 28 Skin Care Now Available in Australia and New Zealand 2Unusual discovery leads to fascinating tuberculosis theory 2Unusual discovery leads to fascinating tuberculosis theory 3New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3
... Seahorse Bioscience, Inc., the leader in the design and ... In Vitro Technologies Pty Ltd as the new distributor ... New Zealand. Seahorse Extracellular Flux Analyzers ... the two major energy producing pathways - mitochondrial respiration ...
... Serono, Inc., an affiliate of Merck KGaA, Darmstadt, ... response letter (CRL) from the U.S. Food and ... (NDA) for Cladribine Tablets, EMD Serono,s proprietary investigational ... relapsing-remitting multiple sclerosis (MS). (Logo: ...
... very sharp object has put Canadian researchers at the National ... Guinness Book of World Records. Only one atom at ... the sharpest man-made object. It is made of Tungsten ... currently being evaluated for its commercial potential., "We did not ...
Cached Biology Technology:Seahorse Bioscience, Inc. Appoints In Vitro Technologies Pty Ltd as New Distributor in Australia and New Zealand 2EMD Serono Receives Complete Response Letter From FDA on Cladribine Tablets New Drug Application 2EMD Serono Receives Complete Response Letter From FDA on Cladribine Tablets New Drug Application 3EMD Serono Receives Complete Response Letter From FDA on Cladribine Tablets New Drug Application 4
Anti-human L-Ficolin, Clone GN4, Monoclonal Antibody...
CD45/CD34 combination 50 tests...
WASF2 Immunogen: WASF2 (NP_008921, 73 a.a. ~ 173 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Rabbit polyclonal to Lck (phospho Y192) ( Abpromise for all tested applications). entrezGeneID: 3932 SwissProtID: P06239...
Biology Products: