Miami Beach, FL (March 5, 2010) Research presented by P&G Beauty & Grooming scientists at the 68th Annual Meeting of the American Academy of Dermatology (Miami Beach, FL, March 5-9) examines skin care science from multiple perspectives, offering insights into how ingredient formulations, care regimens and gene expressions impact skin condition. Eleven studies are on display, discussing a wide range of topics, including lipid metabolism pathways in the stratum corneum, skin elasticity and male shaving regimens.
"This year, P&G Beauty & Grooming is presenting a diverse research portfolio covering topics such as male and female skin condition, whole body anti-aging treatments and skin care genomics," said Emma Kohring, Global Director, P&G Beauty & Grooming Science. "The 2010 American Academy of Dermatology (AAD) Annual Meeting is the ideal venue for P&G Beauty & Grooming scientists to share their research and discuss the findings with leaders in the world of dermatology."
The following research summaries are just a sample of the P&G Beauty & Grooming science that will be shared at the AAD Annual Meeting.
Hexamidine, a Protease Inhibitor, Promotes Stratum Corneum Lipid Biomarkers In Vitro (P104, PD 01)
Skin aging is a result of unrepaired damage as well as age-related physiological changes. The factors that accelerate skin aging are both intrinsic, such as free radicals, and extrinsic, such as UV exposure. In both intrinsically and extrinsically aged skin, there is a down-regulation of the gene expression involved in stratum corneum (the outer layer of the skin) lipid biosynthesis and metabolism, resulting in decreased levels of key lipids available for maintenance and repair.
P&G Beauty & Grooming scientists evaluated how hexamidine impacts the gene expression of stratum corneum (SC) lipid metabolism pathways in vitro. Using gene chip technology, scientists examined RNA from skin biopsies of young and older stud
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