Navigation Links
Oxidative stress, mitochondrial damage and neurodegenerative diseases
Date:8/8/2013

Oxidative stress and mitochondrial damage have been implicated in the pathogenesis of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. Oxidative stress is characterized by the overproduction of reactive oxygen species, which can induce mitochondrial DNA mutations, damage the mitochondrial respiratory chain, alter membrane permeability, and influence Ca2+ homeostasis and mitochondrial defense systems. All these changes are implicated in the development of these neurodegenerative diseases, mediating or amplifying neuronal dysfunction and triggering neurodegeneration. A recent article published in the Neural Regeneration Research (Vol. 8, No. 21, 2013), entitled "Oxidative stress, mitochondrial damage and neurodegenerative diseases", summarizes the contribution of oxidative stress and mitochondrial damage to the onset of neurodegenerative diseases and discusses strategies to modify mitochondrial dysfunction that may be attractive therapeutic interventions for the treatment of various neurodegenerative diseases.


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert

Page: 1

Related biology news :

1. Oxidative stress and altered gene expression occurs in a metabolic liver disease model
2. Red hair is a sign of oxidative stress in wild boars, but gray is a-ok
3. Loneliness, like chronic stress, taxes the immune system
4. Climate change increases stress, need for restoration on grazed public lands
5. Rare mitochondrial mutations -- maybe not so rare?
6. Biologists map rare case of fitness-reducing interaction in nuclear, mitochondrial DNA
7. Mitochondrial mutations: When the cells 2 genomes collide
8. FASEB SRC announces conference: Mitochondrial Assembly & Dynamics in Health, Disease & Aging
9. Discovery of a new family of key mitochondrial proteins for the function and viability of the brain
10. MS research could help repair damage affecting nerves
11. Early exposure to bisphenol A might damage the enamel of teeth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/11/2016)... 2016 http://www.apimages.com ) - --> ... available at AP Images ( http://www.apimages.com ) - ... to produce the new refugee identity cards. DERMALOG will be unveiling ... in Hanover next week.   --> ... used to produce the new refugee identity cards. DERMALOG will be ...
(Date:3/9/2016)... Germany , March 9, 2016 ... country,s government identified that more than 23,000 public service ... or had been receiving their salary unlawfully.    ... African country,s government identified that more than 23,000 public ... name or had been receiving their salary unlawfully.    ...
(Date:3/3/2016)... and DE SOTO, Kansas , ... Stroke Detection Plus® to offer Oncimmune,s Early CDT®-Lung, ... and early detection of lung cancer Early ... unions and individuals. --> Early CDT®-Lung test ... individuals. --> Oncimmune, a leader in early ...
Breaking Biology News(10 mins):
(Date:5/3/2016)... , ... May 03, 2016 , ... In a list ... out of the state’s 76 fastest-growing private companies; a small percentage of the state's ... ranked organizations on the percent change in revenue from 2012 to 2015. ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... addition of Dr. Nancy Gillett to its Board of Directors. Dr. Gillett recently ... as Corporate Executive Vice President and Chief Scientific Officer. A board-certified veterinary pathologist, ...
(Date:5/3/2016)... (PRWEB) , ... May 03, 2016 , ... ... NeuroTech NYC , the sensor and data driven conferences, will take place on June 7-8, ... UnitedHealth's Vidya Raman-Tangella on incorporating technology -- including AR/VR, machine learning, ...
(Date:5/3/2016)... May 3, 2016  Dr. Thomas P. McHugh ... The Woodlands, Texas , now offers ... of treated fat cells in just 25-minutes, leaving a ... 90 percent of Americans report feeling bothered by excess ... reduction procedures are a growing industry. This innovative new ...
Breaking Biology Technology: