Navigation Links
Our internal clocks can become ticking time bombs for diabetes and obesity
Date:4/1/2013

If you're pulling and all-nighter to finish a term paper, a new parent up all night with a fussy baby, or simply can't sleep like you once could, then you may be snoozing on good health. That's because new research published in The FASEB Journal used mice to show that proper sleep patterns are critical for healthy metabolic function, and even mild impairment in our circadian rhythms can lead to serious health consequences, including diabetes and obesity.

"We should acknowledge the unforeseen importance of our 24-hour rhythms for health," said Claudia Coomans, Ph.D., a researcher involved in the work from the Department of Molecular Cell Biology in the Laboratory of Neurophysiology at Leiden University Medical Center in Leiden, Netherlands. "To quote Seneca 'We should live according to nature (secundum naturam vivere).'"

To make this discovery, Coomans and colleagues exposed mice to constant light, which disturbed their normal internal clock function, and observed a gradual degradation of their bodies' internal clocks until it reached a level that normally occurs when aging. Eventually the mice lost their 24-hour rhythm in energy metabolism and insulin sensitivity, indicating that relatively mild impairment of clock function had severe metabolic consequences.

"The good news is that some of us can 'sleep it off' to avoid obesity and diabetes," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "The bad news is that we can all get the metabolic doldrums when our normal day/night cycle is disrupted."


'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1

Related biology news :

1. In protein folding, internal friction may play a more significant role than previously thought
2. Nanoparticles added to platelets double internal injury survival rate
3. Annals of Internal Medicine tip sheet for Sept. 4, 2012
4. Internal relations
5. Long-term preservation: Pensoft Publishers partner with the CLOCKSS Archive
6. Dartmouth research: The clocks are ticking and the climate is changing
7. Snooze button on biological clocks improves cell adaptability
8. Research secured for the future: Pensoft Publishers takes on CLOCKSS archival technology
9. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
10. From scourge to saint: E. coli bacteria becomes a factory - to make cheaper, faster pharmaceuticals
11. Has modern science become dysfunctional?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/13/2016)... 2016 http://www.researchandmarkets.com/research/7h6hnn/india_biometrics ... the  "India Biometrics Authentication & Identification ...  report to their offering.  ... the addition of the  "India Biometrics ... & Forecast (2015-2020)"  report to ...
(Date:1/8/2016)... MANCHESTER, United Kingdom , Jan. 8, 2016 /PRNewswire/ ... sensor-based diagnostic products, today announced the closing of a $9 ... investors.  Proceeds from the financing will be used to accelerate ... device for detecting early-stage pressure ulcers. ... after receiving CE Mark approval. The device,s introduction has been ...
(Date:1/7/2016)... 2016 Various factors have contributed to ... as biologics and biosimilars. Some of these factors ... growing demand for cost-effective alternatives, growing burden of ... similar versions of their corresponding patented biologic drugs, ... safety, and efficacy. The global biosimilars market is ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... ... , ... Bulk food product inspection systems are specifically designed ... the production process. Despite frequently inspecting loose product prior to packaging, product inspection ... sacks of dry powders. , Mettler-Toledo Product Inspection's brand-new white paper entitled "Improving ...
(Date:2/8/2016)... the development of future natural products for crop protection. In ... center in Israel and invests substantial ... has a variety of products adapted to regional needs, ... than 35 counties worldwide. ... Gold ® is used to control a broad spectrum ...
(Date:2/6/2016)... McLean, VA (PRWEB) , ... February 06, 2016 , ... ... enrichment session, cost-free, for middle and high school teachers on Wednesday February 10, 2016. ... be held at the Smithsonian-Mason School of Conservation, located at 1500 Remount Road in ...
(Date:2/5/2016)... , Feb. 5, 2016  In the pharmaceutical industry ... a host of launch activities including the identification and ... launch activity is especially high in the oncology therapeutic ... Best Practices and the Role of Medical Affairs in ... focused on oncology therapies find better ways to utilize ...
Breaking Biology Technology: